Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ekta Dembla"'
Autor:
Amrita Mukherjee, Rashmi Katiyar, Ekta Dembla, Mayur Dembla, Praveen Kumar, Anouar Belkacemi, Martin Jung, Andreas Beck, Veit Flockerzi, Karin Schwarz, Frank Schmitz
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101830- (2020)
Summary: Multiple sclerosis (MS) is a demyelinating disease caused by an auto-reactive immune system. Recent studies also demonstrated synapse dysfunctions in MS patients and MS mouse models. We previously observed decreased synaptic vesicle exocytos
Externí odkaz:
https://doaj.org/article/2347bc37190e414885db72c0df12eefa
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
In the present study, we generated and characterized a splice site-specific monoclonal antibody that selectively detects the calcineurin-binding dynamin1 splice variant dynamin1xb. Calcineurin is a Ca2+-regulated phosphatase that enhances dynamin1 ac
Externí odkaz:
https://doaj.org/article/e70411b52cc945edbb835cc82f0d2da6
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-20 (2020)
Scientific Reports
Scientific Reports
Rod photoreceptor synapses use large, ribbon-type active zones for continuous synaptic transmission during light and dark. Since ribbons are physically connected to the active zones, we asked whether illumination-dependent changes of ribbons influenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2469d8a884a0899298bcaed82808f1
http://link.springer.com/article/10.1038/s41598-020-62734-0
http://link.springer.com/article/10.1038/s41598-020-62734-0
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10789, p 10789 (2021)
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10789, p 10789 (2021)
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system that finally leads to demyelination. Demyelinating optic neuritis is a frequent symptom in MS. Recent studies also revealed synapse dysfunctions in MS patients and MS mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b3d43eb8bdf2a28caea1b26263e421
https://pubmed.ncbi.nlm.nih.gov/34639129
https://pubmed.ncbi.nlm.nih.gov/34639129
Autor:
Ekta Dembla, Ute Becherer
Large dense core vesicle (LDCVs) biogenesis in neuroendocrine cells involves: (a) production of cargo peptides processed in the Golgi; (b) fission of cargo loaded LDCVs undergoing maturation steps; (c) movement of these LDCVs to the plasma membrane.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7265bfa7a326621d87a8741c9dbdf27
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
In the present study, we generated and characterized a splice site-specific monoclonal antibody that selectively detects the calcineurin-binding dynamin1 splice variant dynamin1xb. Calcineurin is a Ca2+-regulated phosphatase that enhances dynamin1 ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f64a6b7a5d4dd49d2788453d77dd4bb
https://doi.org/10.3389/fnmol.2017.00230
https://doi.org/10.3389/fnmol.2017.00230
Large dense core vesicle (LDCV) exocytosis in chromaffin cells follows a well characterized process consisting of docking, priming, and fusion. Total internal reflection fluorescence microscopy (TIRFM) studies suggest that some LDCVs, although being
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d51509214153db6de374975f878d14
https://europepmc.org/articles/PMC6618444/
https://europepmc.org/articles/PMC6618444/