Zobrazeno 1 - 10 of 439 pro vyhledávání: '"Eksterowicz J"'
1
Akademický článek
Targeting Androgen, Thyroid Hormone, and Vitamin A and D Receptors to Treat Prostate Cancer.
Autor: Hantusch, Brigitte1,2 (AUTHOR) brigitte.hantusch@meduniwien.ac.at, Kenner, Lukas1,2,3,4,5,6 (AUTHOR) lukas.kenner@meduniwien.ac.at, Stanulović, Vesna S.7 (AUTHOR) v.stanulovic@bham.ac.uk, Hoogenkamp, Maarten7 (AUTHOR) m.hoogenkamp@bham.ac.uk, Brown, Geoffrey8 (AUTHOR) lukas.kenner@meduniwien.ac.at
Publikováno v: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 17, p9245. 29p.
Zobrazit plný text záznamu
2
Akademický článek
Orally Bioavailable Small-Molecule CD73 Inhibitor (OP-5244) Reverses Immunosuppression through Blockade of Adenosine Production.
Autor: Du X; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Moore J; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Blank BR; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Eksterowicz J; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Sutimantanapi D; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Yuen N; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Metzger T; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Chan B; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Huang T; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Chen X; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Chen Y; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Duong F; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Kong W; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Chang JH; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Sun J; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Zavorotinskaya T; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Ye Q; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Junttila MR; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Ndubaku C; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Friedman LS; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Fantin VR; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States., Sun D; ORIC Pharmaceuticals, 240 E. Grand Avenue, Floor 2, South San Francisco, California 94080, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Sep 24; Vol. 63 (18), pp. 10433-10459. Date of Electronic Publication: 2020 Sep 09.
Zobrazit plný text záznamu
3
Akademický článek
Insights into the Interaction Mechanisms of Peptide and Non-Peptide Inhibitors with MDM2 Using Gaussian-Accelerated Molecular Dynamics Simulations and Deep Learning.
Autor: Yang, Wanchun1 (AUTHOR) wangjian_lxy@sdjtu.edu.cn, Wang, Jian1 (AUTHOR), Zhao, Lu1 (AUTHOR), Chen, Jianzhong1 (AUTHOR) yangwch1982@126.com
Publikováno v: Molecules. Jul2024, Vol. 29 Issue 14, p3377. 22p.
Zobrazit plný text záznamu
4
Akademický článek
Targeting Hdm2 and Hdm4 in Anticancer Drug Discovery: Implications for Checkpoint Inhibitor Immunotherapy.
Autor: Ntwasa, Monde1 (AUTHOR) ntwasmm@unisa.ac.za
Publikováno v: Cells (2073-4409). Jul2024, Vol. 13 Issue 13, p1124. 11p.
Zobrazit plný text záznamu
5
Akademický článek
Discovery of a Potent Steroidal Glucocorticoid Receptor Antagonist with Enhanced Selectivity against the Progesterone and Androgen Receptors (OP-3633).
Autor: Du X; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Eksterowicz J; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Zhou H; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Rew Y; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Zhu L; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Yan X; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Medina JC; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Huang T; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Chen X; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Sutimantanapi D; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Jahchan N; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Kong W; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Sun J; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Zavorotinskaya T; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Ye Q; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Fantin VR; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Sun D; ORIC Pharmaceuticals , 240 E. Grand Avenue, Fl2 , South San Francisco , California 94080 , United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2019 Jul 25; Vol. 62 (14), pp. 6751-6764. Date of Electronic Publication: 2019 Jul 05.
Zobrazit plný text záznamu
6
Akademický článek
Discovery of a Potent and Selective Steroidal Glucocorticoid Receptor Antagonist (ORIC-101).
Autor: Rew Y; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Du X; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Eksterowicz J; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Zhou H; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Jahchan N; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Zhu L; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Yan X; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Kawai H; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., McGee LR; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Medina JC; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Huang T; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Chen C; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Zavorotinskaya T; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Sutimantanapi D; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Waszczuk J; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Jackson E; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Huang E; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Ye Q; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Fantin VR; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States., Sun D; ORIC Pharmaceuticals , 240 East Grand Avenue, Fl2 , South San Francisco , California 94080 , United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2018 Sep 13; Vol. 61 (17), pp. 7767-7784. Date of Electronic Publication: 2018 Aug 23.
Zobrazit plný text záznamu
7
Akademický článek
Targeting MDM2 in malignancies is a promising strategy for overcoming resistance to anticancer immunotherapy.
Autor: Sun, Dantong1,2 (AUTHOR), Qian, Haili2 (AUTHOR) qianhaili001@163.com, Li, Junling1 (AUTHOR) lijunling@cicams.ac.cn, Xing, Puyuan1 (AUTHOR) xingpuyuan@cicams.ac.cn
Publikováno v: Journal of Biomedical Science. 1/29/2024, Vol. 31 Issue 1, p1-12. 12p.
Zobrazit plný text záznamu
8
Akademický článek
The oncogenic mechanisms of the Janus kinase-signal transducer and activator of transcription pathway in digestive tract tumors.
Autor: Zhao, Ruihong1 (AUTHOR), Hu, Zhangmin1 (AUTHOR), Zhang, Xiaoli1 (AUTHOR), Huang, Shujuan1 (AUTHOR), Yu, Guodong1 (AUTHOR), Wu, Zhe1 (AUTHOR), Yu, Wei1 (AUTHOR), Lu, Juan1 (AUTHOR) lujuanzju@zju.edu.cn, Ruan, Bing1 (AUTHOR) ruanbing@zju.edu.cn
Publikováno v: Cell Communication & Signaling. 1/25/2024, Vol. 22 Issue 1, p1-18. 18p.
Zobrazit plný text záznamu
9
Akademický článek
Recent Progress in CDK4/6 Inhibitors and PROTACs.
Autor: Wang, Hao1 (AUTHOR), Ba, Jianfei1 (AUTHOR), Kang, Yue1 (AUTHOR), Gong, Zeqiao1 (AUTHOR), Liang, Tingting1 (AUTHOR), Zhang, Yahong1 (AUTHOR), Qi, Jianguo1 (AUTHOR) qijianguo@henu.edu.cn, Wang, Jianhong1 (AUTHOR) qijianguo@henu.edu.cn
Publikováno v: Molecules. Dec2023, Vol. 28 Issue 24, p8060. 23p.
Zobrazit plný text záznamu
10
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje