Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ekramy E, Sayedahmed"'
Autor:
Nelly O. Elshafie, Michael Gribskov, Nathanael I. Lichti, Ekramy E. Sayedahmed, Michael O. Childress, Andrea Pires dos Santos
Publikováno v:
FEBS Open Bio, Vol 14, Iss 11, Pp 1899-1913 (2024)
Diffuse large B‐cell lymphoma (DLBCL) is the most prevalent subtype of non‐Hodgkin lymphoma (NHL) in domestic dogs, with many similarities to its human counterpart. The progression of the disease is rapid, and treatment must be initiated early to
Externí odkaz:
https://doaj.org/article/9a51b6ad30a04c1087d67b5b84f7f347
Autor:
Ekramy E. Sayedahmed, Marcelo Valdemir Araújo, Taiana Tainá Silva-Pereira, Shubhada K. Chothe, Ahmed Elkashif, Marwa Alhashimi, Wen-Chien Wang, Andrea P. Santos, Meera Surendran Nair, Abhinay Gontu, Ruth Nissly, Antônio Francisco de Souza Filho, Mariana Silva Tavares, Marina Caçador Ayupe, Caio Loureiro Salgado, Érika Donizetti de Oliveira Candido, Danielle Bruna Leal Oliveira, Edison Luiz Durigon, Marcos Bryan Heinemann, Denise Morais da Fonseca, Chinnaswamy Jagannath, Ana Marcia Sá Guimarães, Suresh V. Kuchipudi, Suresh K. Mittal
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 194-207 (2023)
Because of continual generation of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it is critical to design the next generation of vaccines to combat the threat posed by SARS-CoV-2 variants. We developed human adenovirus
Externí odkaz:
https://doaj.org/article/4546dbaeda5b4dfa95545d2dbef95e54
Autor:
Ekramy E. Sayedahmed, Nelly O. Elshafie, GuangJun Zhang, Sulma I. Mohammed, Suryaprakash Sambhara, Suresh K. Mittal
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionNonhuman adenoviral (AdV) gene delivery platforms have significant value due to their ability to elude preexisting AdV vector immunity in most individuals. Previously, we have demonstrated that intranasal (IN) immunization of mice with BA
Externí odkaz:
https://doaj.org/article/94c6a6041d594650abb015b716073724
Autor:
Nelly O. Elshafie, Michael Gribskov, Nathanael I. Lichti, Ekramy. E. Sayedahmed, Michael O. Childress, Andrea P. dos Santos
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionLymphoma is a common canine cancer with translational relevance to human disease. Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype, contributing to almost fifty percent of clinically recognized lymphoma cases. Identifyin
Externí odkaz:
https://doaj.org/article/04fc2831d5954499ab23d537c439878e
Autor:
Ekramy E. Sayedahmed, Nelly O. Elshafie, Andrea P. dos Santos, Chinnaswamy Jagannath, Suryaprakash Sambhara, Suresh K. Mittal
Publikováno v:
Vaccines, Vol 12, Iss 2, p 157 (2024)
The nucleoprotein (NP) is a vital target for the heterosubtypic immunity of CD8+ cytotoxic T lymphocytes (CTLs) due to its conservation among influenza virus subtypes. To further enhance the T cell immunity of NP, autophagy-inducing peptide C5 (AIP-C
Externí odkaz:
https://doaj.org/article/5db201f60a3540b78f779c4abf24a943
Publikováno v:
Viruses, Vol 14, Iss 12, p 2727 (2022)
An adenoviral (AdV)-based vector system is a promising platform for vaccine development and gene therapy applications. Administration of an AdV vector elicits robust innate immunity, leading to the development of humoral and cellular immune responses
Externí odkaz:
https://doaj.org/article/9913642ee35247c0abff3956205e660e
Autor:
Nelly O. Elshafie, Jessica Hanlon, Mays Malkawi, Ekramy E. Sayedahmed, Lynn F. Guptill, Yava L. Jones-Hall, Andrea P. Santos
Publikováno v:
Veterinary Sciences, Vol 9, Iss 8, p 444 (2022)
Pythium insidiosum is an infectious oomycete affecting dogs that develop the cutaneous or gastrointestinal form of pythiosis with a poor prognosis. If left untreated, pythiosis may be fatal. This organism is not a true fungus because its cell wall an
Externí odkaz:
https://doaj.org/article/5fe6a58c8af844d885ea09ebe4768623
Publikováno v:
Viruses, Vol 14, Iss 8, p 1684 (2022)
Influenza viruses are responsible for millions of cases globally and significantly threaten public health. Since pandemic and zoonotic influenza viruses have emerged in the last 20 years and some of the viruses have resulted in high mortality in huma
Externí odkaz:
https://doaj.org/article/f4c66ab2593146d4a852cec0902dd050
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 10, Pp n/a-n/a (2021)
Abstract Since the development of the first vaccine against smallpox over two centuries ago, vaccination strategies have been at the forefront of significantly impacting the incidences of infectious diseases globally. However, the increase in the hum
Externí odkaz:
https://doaj.org/article/2d0493b19cb14e73a6c532391c408cd4
Autor:
Ekramy E. Sayedahmed, Ahmed O. Hassan, Rashmi Kumari, Weiping Cao, Shivaprakash Gangappa, Ian York, Suryaprakash Sambhara, Suresh K. Mittal
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 210-222 (2018)
Several human and nonhuman adenovirus (AdV) vectors including bovine AdV type 3 (BAdV-3) were developed as gene delivery vectors to supplement and/or elude human AdV (HAdV)-specific neutralizing antibodies (vector immunity). Here we evaluated the vac
Externí odkaz:
https://doaj.org/article/4840ace576694863bc75bc2475799085