Membrane-Interacting DNA Nanotubes Induce Cancer Cell Death

Autor: Samet Kocabey, Aslihan Ekim Kocabey, Roger Schneiter, Curzio Rüegg

Publikováno v: Nanomaterials, Vol 11, Iss 8, p 2003 (2021)

DNA nanotechnology offers to build nanoscale structures with defined chemistries to precisely position biomolecules or drugs for selective cell targeting and drug delivery. Owing to the negatively charged nature of DNA, for delivery purposes, DNA is

Externí odkaz: https://doaj.org/article/c40beab9c17a4ef2813c1ce90cd6489f

Human lipocalins bind and export fatty acids through the secretory pathway of yeast cells.

Autor: Ekim Kocabey A; Department of Biology, University of Fribourg, Fribourg, Switzerland., Schneiter R; Department of Biology, University of Fribourg, Fribourg, Switzerland.

Publikováno v: Frontiers in microbiology [Front Microbiol] 2024 Jan 05; Vol. 14, pp. 1309024. Date of Electronic Publication: 2024 Jan 05 (Print Publication: 2023).

Prostate secretory protein 94 inhibits sterol binding and export by the mammalian CAP protein CRISP2 in a calcium-sensitive manner

Autor: Ola El Atab, Aslihan Ekim Kocabey, Oluwatoyin A. Asojo, Roger Schneiter

Publikováno v: The Journal of biological chemistry. 298(3)

Members of the CAP protein superfamily are present in all kingdoms of life and have been implicated in many different processes, including pathogen defense, immune evasion, sperm maturation, and cancer progression. Most CAP proteins are secreted glyc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f42556445466f1f2e1dafd024e211879
https://pubmed.ncbi.nlm.nih.gov/35063506

The antioxidant function of Sco proteins depends on a critical surface-exposed residue

Autor: Gerhard Rödel, Uta Gey, Aslihan Ekim Kocabey

Publikováno v: Biochimica et biophysica acta. General subjects. 1865(2)

Background Besides their role in copper metabolism, Sco proteins from different organisms have been shown to play a defensive role against oxidative stress. In the present study, we set out to identify crucial amino acid residues for the antioxidant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f2e12d8c32b1f76668d50cd8d8f1e0
https://pubmed.ncbi.nlm.nih.gov/33171213

The oleaginous yeast Starmerella bombicola reveals limitations of Saccharomyces cerevisiae as a model for fatty acid transport studies.

Autor: Salvador Lopez JM; Centre for Synthetic Biology, Ghent University, Belgium., Jezierska S; Centre for Synthetic Biology, Ghent University, Belgium.; Avecom N.V., Industrieweg 122P 9032 Wondelgem, Belgium., Ekim Kocabey A; Department of Biology, Fribourg University, Switzerland., Lee J; Centre for Synthetic Biology, Ghent University, Belgium., Schneiter R; Department of Biology, Fribourg University, Switzerland., Van Bogaert INA; Centre for Synthetic Biology, Ghent University, Belgium.

Publikováno v: FEMS yeast research [FEMS Yeast Res] 2022 Nov 22; Vol. 22 (1).