Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Ekaterina Y. Ilyechova"'
1
Akademický článek
Influence of Silver Nanoparticles on the Growth of Ascitic and Solid Ehrlich Adenocarcinoma: Focus on Copper Metabolism
Autor: Daria N. Magazenkova, Ekaterina A. Skomorokhova, Mohammad Al Farroukh, Maria S. Zharkova, Zena M. Jassem, Valeria E. Rekina, Olga V. Shamova, Ludmila V. Puchkova, Ekaterina Y. Ilyechova
Publikováno v: Pharmaceutics, Vol 15, Iss 4, p 1099 (2023)
The link between copper metabolism and tumor progression motivated us to use copper chelators for suppression of tumor growth. We assume that silver nanoparticles (AgNPs) can be used for lowering bioavailable copper. Our assumption is based on the ab
Externí odkaz: https://doaj.org/article/82382de037a34c298e7de0491b0163e8
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2
Akademický článek
Silver Ions as a Tool for Understanding Different Aspects of Copper Metabolism
Autor: Ludmila V. Puchkova, Massimo Broggini, Elena V. Polishchuk, Ekaterina Y. Ilyechova, Roman S. Polishchuk
Publikováno v: Nutrients, Vol 11, Iss 6, p 1364 (2019)
In humans, copper is an important micronutrient because it is a cofactor of ubiquitous and brain-specific cuproenzymes, as well as a secondary messenger. Failure of the mechanisms supporting copper balance leads to the development of neurodegenerativ
Externí odkaz: https://doaj.org/article/883baf1373c94ffa9b533d20459cc2c7
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3
Akademický článek
CRISP-R/Cas9 Mediated Deletion of Copper Transport Genes CTR1 and DMT1 in NSCLC Cell Line H1299. Biological and Pharmacological Consequences
Autor: Ekaterina Y. Ilyechova, Elisa Bonaldi, Iurii A. Orlov, Ekaterina A. Skomorokhova, Ludmila V. Puchkova, Massimo Broggini
Publikováno v: Cells, Vol 8, Iss 4, p 322 (2019)
Copper, the highly toxic micronutrient, plays two essential roles: it is a catalytic and structural cofactor for Cu-dependent enzymes, and it acts as a secondary messenger. In the cells, copper is imported by CTR1 (high-affinity copper transporter 1)
Externí odkaz: https://doaj.org/article/4b3cf324260c4ec393312813d2836dd4
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4
Akademický článek
Copper Metabolism of Newborns Is Adapted to Milk Ceruloplasmin as a Nutritive Source of Copper: Overview of the Current Data
Autor: Ludmila V. Puchkova, Polina S. Babich, Yulia A. Zatulovskaia, Ekaterina Y. Ilyechova, Francesca Di Sole
Publikováno v: Nutrients, Vol 10, Iss 11, p 1591 (2018)
Copper, which can potentially be a highly toxic agent, is an essential nutrient due to its role as a cofactor for cuproenzymes and its participation in signaling pathways. In mammals, the liver is a central organ that controls copper turnover through
Externí odkaz: https://doaj.org/article/04befffbd3fd4bfb8d835abe6edde42c
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7
Synthetic Lethality Screening Identifies FDA-Approved Drugs that Overcome ATP7B-Mediated Tolerance of Tumor Cells to Cisplatin
Autor: Raffaele La Montagna, Ludmila V. Puchkova, Marta Mariniello, Luca Giorgio Wanderlingh, Roberta Crispino, Annamaria Carissimo, Ekaterina Y. Ilyechova, Raffaella Petruzzelli, Michael M. Galagudza, Angela Amoresano, Francesca Pane, Roman S. Polishchuk, Diego L. Medina, Federico Catalano
Publikováno v: Cancers (Basel) (2020). doi:10.3390/cancers12030608
info:cnr-pdr/source/autori:Marta Mariniello, Raffaella Petruzzelli, Luca G Wanderlingh, Raffaele La Montagna, Annamaria Carissimo, Francesca Pane, Angela Amoresano Ekaterina Y Ilyechova Michael M Galagudza Federico Catalano, Roberta Crispino, Ludmila V Puchkova, Diego L Medina, Roman S Polishchuk/titolo:Synthetic Lethality Screening Identifies FDA-Approved Drugs that Overcome ATP7B-Mediated Tolerance of Tumor Cells to Cisplatin/doi:10.3390%2Fcancers12030608/rivista:Cancers (Basel)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume
Cancers
Cancers (Basel) 12 (2020). doi:10.3390/cancers12030608
info:cnr-pdr/source/autori:Mariniello, Marta; Petruzzelli, Raffaella; Wanderlingh, Luca G.; La Montagna, Raffaele; Carissimo, Annamaria; Pane, Francesca; Amoresano, Angela; Ilyechova, Ekaterina Y.; Galagudza, Michael M.; Catalano, Federico; Crispino, Roberta; Puchkova, Ludmila V.; Medina, Diego L.; Polishchuk, Roman S./titolo:Synthetic Lethality Screening Identifies FDA-Approved Drugs That Overcome ATP7B-Mediated Tolerance of Tumor Cells to Cisplatin/doi:10.3390%2Fcancers12030608/rivista:Cancers (Basel)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:12
Volume 12
Issue 3
Cancers, Vol 12, Iss 3, p 608 (2020)
Tumor resistance to chemotherapy represents an important challenge in modern oncology. Although platinum (Pt)-based drugs have demonstrated excellent therapeutic potential, their effectiveness in a wide range of tumors is limited by the development o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e610e54767670bb8df33a1928da0066
https://publications.cnr.it/doc/455294
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8
New silver nanoparticles induce apoptosis-like process in E. coli and interfere with mammalian copper metabolism
Autor: Pavel N. Brunkov, Ekaterina Y. Ilyechova, Ilya M. Sosnin, Alexey E. Romanov, Polina S. Babich, Demid A. Kirilenko, Gennadii L Ataev, Iurii A. Orlov, L. V. Puchkova, Tatiana P Sankova
Publikováno v: International Journal of Nanomedicine. 11:6561-6574
Silver nanoparticles (SNPs) are new functional materials that are widely used in biomedical and industrial technologies. Two main features that make SNPs valuable are their strong antibacterial effects and low toxicity to eukaryotes. In this study, S
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea40788139f5ac49d91b22d5a56b4e71
https://doi.org/10.2147/ijn.s117745
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9
Case of Early-Onset Parkinson’s Disease in a Heterozygous Mutation Carrier of the ATP7B Gene
Autor: Ludmila V. Puchkova, Ekaterina Y. Ilyechova, Sergey A. Samsonov, Iurii A. Orlov, Irina Miliukhina, Marina N. Karpenko
Publikováno v: Journal of Personalized Medicine, Vol 9, Iss 3, p 41 (2019)
Journal of Personalized Medicine
In this paper, we report a clinically proven case of Parkinson’s disease (PD) with early onset in a patient who is a heterozygous mutation carrier of ATP7B (the Wilson’s disease gene). The patient was observed from 2011 to 2018 in the Center for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26755dd87dca4910ac768b73b69ea196
https://www.mdpi.com/2075-4426/9/3/41
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10
Activation of autophagy, observed in liver tissues from patients with Wilson disease and from Atp7b-deficient animals, protects hepatocytes from copper-induced apoptosis
Autor: Federico Pietrocola, Ekaterina Y. Ilyechova, Alessia Romano, Assunta Merolla, Mafalda Concilli, Rossella De Cegli, Ludmila V. Puchkova, Andree Zibert, Josef Lichtmannegger, Hartmut Schmidt, Giusy Ranucci, Brunella Franco, Elia Di Schiavi, Sabine Borchard, Raffaella Petruzzelli, Roberta Crispino, Claudia Einer, Raffaele Iorio, Alessia Indrieri, Elena V. Polishchuk, Marta Mariniello, Hans Zischka, Roman S. Polishchuk, Guido Kroemer
Publikováno v: Gastroenterology (N.Y.N.Y., 1943) 156 (2019): 1173–1189. doi:10.1053/j.gastro.2018.11.032
info:cnr-pdr/source/autori:Polishchuk, Elena, V; Merolla, Assunta; Lichtmannegger, Josef; Romano, Alessia; Indrieri, Alessia; Ilyechova, Ekaterina Y.; Concilli, Mafalda; De Cegli, Rossella; Crispino, Roberta; Mariniello, Marta; Petruzzelli, Raffaella; Ranucci, Giusy; Iorio, Raffaele; Pietrocola, Federico; Einer, Claudia; Borchard, Sabine; Zibert, Andree; Schmidt, Hartmut H.; Di Schiavi, Elia; Puchkova, Ludmila, V; Franco, Brunella; Kroemer, Guido; Zischka, Hans; Polishchuk, Roman S./titolo:Activation of Autophagy, Observed in Liver Tissues From Patients With Wilson Disease and From ATP7B-Deficient Animals, Protects Hepatocytes From Copper-Induced Apoptosis/doi:10.1053%2Fj.gastro.2018.11.032/rivista:Gastroenterology (N.Y.N.Y., 1943)/anno:2019/pagina_da:1173/pagina_a:1189/intervallo_pagine:1173–1189/volume:156
Gastroenterology 156, 1173-1189.e5 (2019)
Gastroenterology (Amst.) (2018).
info:cnr-pdr/source/autori:Elena V. Polishchuk, Assunta Merolla, Josef Lichtmannegger, Alessia Romano, Alessia Indrieri, Ekaterina Y. Ilyechova, Mafalda Concilli, Rossella De Cegli, Roberta Crispino, Marta Mariniello, Raffaella Petruzzelli, Giusy Ranucci, Raffaele Iorio, Federico Pietrocola, Claudia Einer, Sabine Borchard, Andree Zibert, Hartmut H. Schmidt, Elia Di Schiavi, Ludmila V. Puchkova, Brunella Franco, Guido Kroemer, Hans Zischka, Roman S. Polishchuk/titolo:Activation of autophagy, observed in liver tissues from patients with Wilson disease and from Atp7b-deficient animals, protects hepatocytes from copper-induced apoptosis/doi:/rivista:Gastroenterology (Amst.)/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume
BACKGROUND & AIMS: Wilson disease (WD) is an inherited disorder of copper metabolism that leads to copper accumulation and toxicity in the liver and brain. It is caused by mutations in the adenosine triphosphatase copper transporting b gene (ATP7B),
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80a72951733eceee6786f4d766cf248
http://hdl.handle.net/11588/724956
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