Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ekaterina Y Steshina"'
Autor:
Igor Y Iskusnykh, Nikolai Fattakhov, Yiran Li, Laure Bihannic, Matthew K Kirchner, Ekaterina Y Steshina, Paul A Northcott, Victor V Chizhikov
Publikováno v:
eLife, Vol 12 (2023)
Development of the nervous system depends on signaling centers – specialized cellular populations that produce secreted molecules to regulate neurogenesis in the neighboring neuroepithelium. In some cases, signaling center cells also differentiate
Externí odkaz:
https://doaj.org/article/a7a09d4cbfff4e7e96e2c9452b75695c
Autor:
Victor V. Chizhikov, Igor Y. Iskusnykh, Ekaterina Y. Steshina, Nikolai Fattakhov, Anne G. Lindgren, Ashwin S. Shetty, Achira Roy, Shubha Tole, Kathleen J. Millen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The contribution of long-range signaling to cortical gyrification remains poorly understood. In this study, authors demonstrate that the combined genetic loss of transcription factors Lmx1a and Lmx1b, expressed in the telencephalic dorsal midline neu
Externí odkaz:
https://doaj.org/article/5e9a3cae7cdf4bcbae7688176c6be113
Autor:
Igor Y. Iskusnykh, Nikolai Fattakhov, Yiran Li, Laure Bihannic, Matthew K. Kirchner, Ekaterina Y. Steshina, Paul A. Northcott, Victor V. Chizhikov
Development of the nervous system depends on signaling centers – specialized cellular populations that produce secreted molecules to regulate neurogenesis in the neighboring neuroepithelium. Some signaling centers also generate key types of neurons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39332c1ce74a61046b836f68bde02c10
https://doi.org/10.1101/2022.10.25.513532
https://doi.org/10.1101/2022.10.25.513532
Autor:
Igor Y. Iskusnykh, Victor V. Chizhikov, Nikolai Fattakhov, Shubha Tole, Achira Roy, Kathleen J. Millen, Ashwin S. Shetty, Ekaterina Y. Steshina, Anne G. Lindgren
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
The extent of neocortical gyrification is an important determinant of a species’ cognitive abilities, yet the mechanisms regulating cortical gyrification are poorly understood. We uncover long-range regulation of this process originating at the tel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525c0e26c1a722217656ebbd6878efaa
https://doi.org/10.1038/s41467-019-12913-z
https://doi.org/10.1038/s41467-019-12913-z
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 36(9)
The brainstem contains diverse neuronal populations that regulate a wide range of processes vital to the organism. Proper cell-fate specification decisions are critical to achieve neuronal diversity in the CNS, but the mechanisms regulating cell-fate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba050fc30b78ed9b1be491a8c92da344
https://pubmed.ncbi.nlm.nih.gov/26937009
https://pubmed.ncbi.nlm.nih.gov/26937009
Autor:
Douglas J. Swanson, Ekaterina Y. Steshina, Paul Wakenight, Kimberly A. Aldinger, Victor V. Chizhikov, Dan Goldowitz, Kathleen J. Millen
Publikováno v:
European Journal of Neuroscience. 32:707-716
ROR-alpha is an orphan nuclear receptor, inactivation of which cell-autonomously blocks differentiation of cerebellar Purkinje cells with a secondary loss of granule neurons. As part of our ENU mutagenesis screen we isolated the recessive tmgc26 mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b1a025e0dacaffd391b7a16d2fba1f9
https://doi.org/10.1111/j.1460-9568.2010.07330.x
https://doi.org/10.1111/j.1460-9568.2010.07330.x
Autor:
Maria V. Samsonova, Ekaterina Y. Steshina, Svetlana Yu. Chikina, Andrei Chernyaev, Alexander G. Chuchalin, I. B. Zborovskaya, Victor V. Chizhikov, Guram Ungiadze, Alexander V. Gasparian, A. G. Tatosyan
Publikováno v:
Oncogene. 21:2398-2405
Ionizing radiation is a potent lung carcinogen, but the precise molecular damage associated with it is still unknown. In this study we investigated cancer-related molecular abnormalities including K-ras (codon 12) mutation, p16(INK4A) promoter hyperm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd05cdcbac09de4faf8385fca2e170f
https://doi.org/10.1038/sj.onc.1205310
https://doi.org/10.1038/sj.onc.1205310
Model organism studies have demonstrated that cell fate specification decisions play an important role in normal brain development. Their role in human neurodevelopmental disorders, however, is poorly understood, with very few examples described. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bdd14fe44e44f51af0a9e0b35b70744
https://europepmc.org/articles/PMC4035921/
https://europepmc.org/articles/PMC4035921/
Autor:
Michael S. Carr, Jennifer V. Schmidt, Elena A. Glick, Oliver K. Appelbe, Ekaterina Y. Steshina, Aleksey Yevtodiyenko
Publikováno v:
BMC Genetics
BMC Genetics, Vol 7, Iss 1, p 44 (2006)
BMC Genetics, Vol 7, Iss 1, p 44 (2006)
BackgroundTheDlk1andGtl2genes define a region of mouse chromosome 12 that is subject to genomic imprinting, the parental allele-specific expression of a gene. Although imprinted genes play important roles in growth and development, the mechanisms by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b88f3ca902ebfb96e081367d614112
https://pubmed.ncbi.nlm.nih.gov/17014736
https://pubmed.ncbi.nlm.nih.gov/17014736
Autor:
Victor V. Chizhikov, Richard Roberts, Linda L. Washburn, Kathleen J. Millen, Ekaterina Y. Steshina, Yesim Ilkin
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 17(10)
Mice homozygous for the dreher (dr) mutation are characterized by pigmentation and skeletal abnormalities and striking behavioral phenotypes, including ataxia, vestibular deficits, and hyperactivity. The ataxia is associated with a cerebellar malform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e5b140329b110f2d570af8c095633d
https://pubmed.ncbi.nlm.nih.gov/17019651
https://pubmed.ncbi.nlm.nih.gov/17019651