The study of the neurotropic activity of the pyrrolopyrimidin-4-ones rearrangement products under the action of phosphorus oxychloride

Autor: Ekaterina V. Zaliznaya, Svetlana A. Varenichenko, Oleg K. Farat, Victor I. Markov

Publikováno v: Журнал органічної та фармацевтичної хімії, Vol 18, Iss 1, Pp 39-44 (2020)

Aim. To synthesize the annelated 4-aminopyridines and study the biological activity of one of products. Results and discussion. In the laboratory of the Research Institute of Biomedical Problems of the Dnipropetrovsk Medical Academy the studies of

Externí odkaz: https://doaj.org/article/8be6ce7524b64f92bb35276dfc0aa6fb

REARRANGEMENT OF SUBSTITUTED 1,3-BENZOXAZINES INTO XANTHENE-TYPE COMPOUNDS

Autor: Svetlana A. Varenichenko, Victor I. Markov, Oleg K. Farat, Ekaterina V. Zaliznaya

Publikováno v: Ukrainian Chemistry Journal. 86:111-122

The rearrangement patterns of new 1,3-benzoxazines derivatives obtained by condensation of substituted salicylamides with cyclic ketones under the influence of Vilsmeier-Haack reagent has been studied. The influence of angel strain in a 4-membered sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3162dae2fbd0b369b93413a10856b40c
https://doi.org/10.33609/0041-6045.86.2.2020.111-122

Synthesis of new hexahydro-5H-indolo[3,2-c]acridines and indolylbutanoic acids by Fischer cyclization of arylhydrazones

Autor: Nikolai V. Smetanin, A. V. Mazepa, Svetlana A. Varenichenko, Ekaterina V. Zaliznaya, Oleg K. Farat, Victor I. Markov

Publikováno v: Chemistry of Heterocyclic Compounds. 54:138-145

Arylhydrazones of 2,3,5,6,7,8-hexahydroacridin-4(1H)-ones and 7-amino-6-(arylhydrazono)-7-oxoheptanoic acids were cyclized by Fischer reaction, providing previously unknown polysubstituted indole derivatives. The starting hydrazones were synthesized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a087099327db728857c3cf3bca93127
https://doi.org/10.1007/s10593-018-2245-7

Взаємодія 4,5-диформіл-2,3,6,7,8,10-гексагідроакридин-8а(1Н)-карбонітрилу з N-нуклеофілами

Autor: Ekaterina V. Zaliznaya, S.А. Varenichenko, O.К. Farat, Victor I. Markov, T.P. Polishuk

Publikováno v: Журнал органічної та фармацевтичної хімії; Том 14, № 3(55) (2016): Журнал органічної та фармацевтичної хімії; 38-42
Žurnal organìčnoï ta farmacevtičnoï hìmìï; Том 14, № 3(55) (2016): Žurnal organìčnoï ta farmacevtičnoï hìmìï; 38-42
Журнал органической и фармацевтической химии; Том 14, № 3(55) (2016): Журнал органической и фармацевтической химии; 38-42

Основи Шиффа становлять практичний інтерес в якості вихідних як для комбінаторного синтезу бібліотек речовин, так і для створення комп�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5507d1bb68003edc8ee3155acb84a72d
https://doi.org/10.24959/ophcj.16.888

Functionalization of tetra- and octahydroacridine derivatives through Michael addition

Autor: Oleg K. Farat, Alexander V. Mazepa, Svetlana A. Varenichenko, Ekaterina V. Zaliznaya, Victor I. Markov

Publikováno v: Tetrahedron Letters. 57:3485-3487

The catalyst-free sp 3 C–H functionalization of tetra- and octahydroacridine derivatives has been achieved using a Michael-type reaction with N -arylmaleimides. This method enables the facile synthesis of biologically important N -aryl or NH pyrrol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f68497cb90cc68315bdc4e14a5699bce
https://doi.org/10.1016/j.tetlet.2016.06.096