Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ekaterina V. Shipova"'
Autor:
Ekaterina V. Shipova, Kent S. Gates
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:2111-2113
A fluorimetric assay for monitoring depurination of the N7-alkylguanine adduct derived from the anticancer natural product leinamycin is described. This general approach could potentially provide the foundation for a high throughput assay that detect
Autor:
Galina V. Pazynina, Nicolai V. Bovin, A. B. Tuzikov, Marina A. Sablina, T. V. Ovchinnikova, Ekaterina V. Shipova, Inna S. Popova
Publikováno v:
Mendeleev Communications. 12:213-215
The sulfated (Su) saccharides 3-Su-Galβ, 3-Su-GalNAcβ, 4-Su-GalNAcβ, 6-Su-GalNAcα, 6-Su-GlcNAcβ, 6-Su-LacNAcβ, 6'-Su-LacNAcβ, 3'-Su-Galβ1-3GlcNAcβ and 3'-Su-Galb1-3GalNAcα, all monosaccharides in D-configuration, have been synthesised in th
Autor:
Puttur Santhoshkumar, Ekaterina V. Shipova, K. Krishna Sharma, Beryl J. Ortwerth, Jaya Bhattacharyya
Publikováno v:
Biochemistry. 46(50)
During aging, human lens proteins undergo several post-translational modifications, one of which is glycation. This process leads to the formation of advanced glycation end products (AGEs) which accumulate with time possibly leading to the formation
Autor:
Ekaterina V. Shipova, M. D. Linetsky
Publikováno v:
Amino acids. 32(2)
Two Lys-Lys crosslinks, 1,3-bis-(5-amino-5-carboxypentyl)-1H-imidazolium (GOLD) and 1,3-bis(5-amino-5-carboxypentyl)-4-methyl-1H-imidazolium (MOLD) salts, have been synthesized by the reaction of imidazole or 4(5)-methyl imidazole with 5-(4-bromobuty
Publikováno v:
Archives of biochemistry and biophysics. 449(1-2)
Incubation of fructose and glutathione leads to the formation of N-2-deoxy-glucos-2-yl glutathione as the major glycation product, with characteristic positive ion at 470 Th in LC-MS spectra. Glutathione disulfide and fructose generate two compounds:
Publikováno v:
Biochimica et biophysica acta. 1724(1-2)
Under the chromatographic conditions used in these studies we observed time- and concentration-dependent formation of N-1-Deoxy-fructos-1-yl glutathione as the major glycation product formed in the mixtures of GSH with glucose. N-1-Deoxy-fructos-1-yl
Autor:
N. V. Bovin, Ekaterina V. Shipova
Publikováno v:
Mendeleev Communications. 10:63-64
The spacer-arm –OCH2CH2CH2NH2 of complex oligosaccharides can be removed by oxidative deamination followed by alkaline β-elimination.
Publikováno v:
Investigative Opthalmology & Visual Science. 50:3311
PURPOSE: To determine whether there are UVA light-responsive sensitizers in young human lenses capable of initiating the oxidation of ascorbic acid in the absence of oxygen. METHODS: Lens homogenates were fractionated, and low-molecular-weight (LMW)
Publikováno v:
Biochimica et Biophysica Acta-Molecular Basis of Disease
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2008, 1782 (1), pp.22. ⟨10.1016/j.bbadis.2007.10.003⟩
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2008, 1782 (1), pp.22. ⟨10.1016/j.bbadis.2007.10.003⟩
Previous studies from this laboratory have shown that there are striking similarities between the yellow chromophores, fluorophores and modified amino acids released by proteolytic digestion from calf lens proteins ascorbylated in vitro and their cou