Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ekaterina V Baranova"'
Autor:
Amand F. Schmidt, Michael V. Holmes, David Preiss, Daniel I. Swerdlow, Spiros Denaxas, Ghazaleh Fatemifar, Rupert Faraway, Chris Finan, Dennis Valentine, Zammy Fairhurst-Hunter, Fernando Pires Hartwig, Bernardo Lessa Horta, Elina Hypponen, Christine Power, Max Moldovan, Erik van Iperen, Kees Hovingh, Ilja Demuth, Kristina Norman, Elisabeth Steinhagen-Thiessen, Juri Demuth, Lars Bertram, Christina M. Lill, Stefan Coassin, Johann Willeit, Stefan Kiechl, Karin Willeit, Dan Mason, John Wright, Richard Morris, Goya Wanamethee, Peter Whincup, Yoav Ben-Shlomo, Stela McLachlan, Jackie F. Price, Mika Kivimaki, Catherine Welch, Adelaida Sanchez-Galvez, Pedro Marques-Vidal, Andrew Nicolaides, Andrie G. Panayiotou, N. Charlotte Onland-Moret, Yvonne T. van der Schouw, Giuseppe Matullo, Giovanni Fiorito, Simonetta Guarrera, Carlotta Sacerdote, Nicholas J. Wareham, Claudia Langenberg, Robert A. Scott, Jian’an Luan, Martin Bobak, Sofia Malyutina, Andrzej Pająk, Ruzena Kubinova, Abdonas Tamosiunas, Hynek Pikhart, Niels Grarup, Oluf Pedersen, Torben Hansen, Allan Linneberg, Tine Jess, Jackie Cooper, Steve E. Humphries, Murray Brilliant, Terrie Kitchner, Hakon Hakonarson, David S. Carrell, Catherine A. McCarty, Kirchner H. Lester, Eric B. Larson, David R. Crosslin, Mariza de Andrade, Dan M. Roden, Joshua C. Denny, Cara Carty, Stephen Hancock, John Attia, Elizabeth Holliday, Rodney Scott, Peter Schofield, Martin O’Donnell, Salim Yusuf, Michael Chong, Guillaume Pare, Pim van der Harst, M. Abdullah Said, Ruben N. Eppinga, Niek Verweij, Harold Snieder, Lifelines Cohort authors, Tim Christen, D. O. Mook-Kanamori, the ICBP Consortium, Stefan Gustafsson, Lars Lind, Erik Ingelsson, Raha Pazoki, Oscar Franco, Albert Hofman, Andre Uitterlinden, Abbas Dehghan, Alexander Teumer, Sebastian Baumeister, Marcus Dörr, Markus M. Lerch, Uwe Völker, Henry Völzke, Joey Ward, Jill P. Pell, Tom Meade, Ingrid E. Christophersen, Anke H. Maitland-van der Zee, Ekaterina V. Baranova, Robin Young, Ian Ford, Archie Campbell, Sandosh Padmanabhan, Michiel L. Bots, Diederick E. Grobbee, Philippe Froguel, Dorothée Thuillier, Ronan Roussel, Amélie Bonnefond, Bertrand Cariou, Melissa Smart, Yanchun Bao, Meena Kumari, Anubha Mahajan, Jemma C. Hopewell, Sudha Seshadri, the METASTROKE Consortium of the ISGC, Caroline Dale, Rui Providencia E. Costa, Paul M. Ridker, Daniel I. Chasman, Alex P. Reiner, Marylyn D. Ritchie, Leslie A. Lange, Alex J. Cornish, Sara E. Dobbins, Kari Hemminki, Ben Kinnersley, Marc Sanson, Karim Labreche, Matthias Simon, Melissa Bondy, Philip Law, Helen Speedy, James Allan, Ni Li, Molly Went, Niels Weinhold, Gareth Morgan, Pieter Sonneveld, Björn Nilsson, Hartmut Goldschmidt, Amit Sud, Andreas Engert, Markus Hansson, Harry Hemingway, Folkert W. Asselbergs, Riyaz S. Patel, Brendan J. Keating, Naveed Sattar, Richard Houlston, Juan P. Casas, Aroon D. Hingorani
Publikováno v:
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background We characterised the phenotypic consequence of genetic variation at the PCSK9 locus and compared findings with recent trials of pharmacological inhibitors of PCSK9. Methods Published and individual participant level data (300,000+
Externí odkaz:
https://doaj.org/article/6496ec7ef17e440a938a2e70da19e20c
Autor:
Ekaterina V Baranova, Fiona Carr, Abirami Veluchamy, Anke H. Maitland-van der Zee, Ana Alfirevic, Moneeza K. Siddiqui, Anette Bygum, Pär Hallberg, Myra White, Eva Rye Rasmussen, Mia Wadelius, Cyrielle Maroteau, Colin N. A. Palmer, Nancy J. Brown, Ann-Christine Syvänen, Patrik K. E. Magnusson, Qun-Ying Yue, Christian von Buchwald, Andrew Cassidy, Malgorzata Karawajczyk, Niclas Eriksson, Katarzyna M Bloch
Publikováno v:
Maroteau, C, Siddiqui, M K, Veluchamy, A, Carr, F, White, M, Cassidy, A J, Baranova, E V, Rasmussen, E R, Eriksson, N, Bloch, K M, Brown, N J, Bygum, A, Hallberg, P, Karawajczyk, M, Magnusson, P K E, Yue, Q-Y, Syvänen, A-C, von Buchwald, C, Alfirevic, A, Maitland-van der Zee, A H, Wadelius, M, Palmer, C N A & PREDICTION-ADR 2020, ' Exome Sequencing Reveals Common and Rare Variants in F5 Associated With ACE Inhibitor and Angiotensin Receptor Blocker-Induced Angioedema ', Clinical Pharmacology and Therapeutics, vol. 108, no. 6, pp. 1195-1202 . https://doi.org/10.1002/cpt.1927
Maroteau, C, Siddiqui, M K, Veluchamy, A, Carr, F, White, M, Cassidy, A J, Baranova, E V, Rasmussen, E R, Eriksson, N, Bloch, K M, Brown, N J, Bygum, A, Hallberg, P, Karawajczyk, M, Magnusson, P K E, Yue, Q Y, Syvänen, A C, von Buchwald, C, Alfirevic, A, Maitland-van der Zee, A H, Wadelius, M, Palmer, C N A & PREDICTION-ADR 2020, ' Exome Sequencing Reveals Common and Rare Variants in F5 Associated With ACE Inhibitor and Angiotensin Receptor Blocker–Induced Angioedema ', Clinical Pharmacology and Therapeutics, vol. 108, no. 6, pp. 1195-1202 . https://doi.org/10.1002/cpt.1927
Clinical pharmacology and therapeutics, 108(6), 1195-1202. Wiley-Blackwell
Maroteau, C, Siddiqui, M K, Veluchamy, A, Carr, F, White, M, Cassidy, A J, Baranova, E V, Rasmussen, E R, Eriksson, N, Bloch, K M, Brown, N J, Bygum, A, Hallberg, P, Karawajczyk, M, Magnusson, P K E, Yue, Q Y, Syvänen, A C, von Buchwald, C, Alfirevic, A, Maitland-van der Zee, A H, Wadelius, M, Palmer, C N A & PREDICTION-ADR 2020, ' Exome Sequencing Reveals Common and Rare Variants in F5 Associated With ACE Inhibitor and Angiotensin Receptor Blocker–Induced Angioedema ', Clinical Pharmacology and Therapeutics, vol. 108, no. 6, pp. 1195-1202 . https://doi.org/10.1002/cpt.1927
Clinical pharmacology and therapeutics, 108(6), 1195-1202. Wiley-Blackwell
Angioedema occurring in the head and neck region is a rare and sometimes life-threatening adverse reaction to angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs). Few studies have investigated the association of
Autor:
Bakhtawar K. Mahmoodi, W.H. Wilson Tang, Frank Dudbridge, Marcus E. Kleber, Ify R. Mordi, Naveed Sattar, Chim C. Lang, Tabassome Simon, Ruth McPherson, Aroon D. Hingorani, Nilesh J. Samani, Imo E. Hoefer, Crystel M. Gijsberts, Winfried März, Michael V. Holmes, Frank L.J. Visseren, Panos Deloukas, Johannes Waltenberger, Claes Held, Alexandre F.R. Stewart, Jaana Hartiala, Anna P. Pilbrow, Kjell Nikus, Guillaume Paré, Ekaterina V Baranova, Nicolas Danchin, Wojciech Szczeklik, Vinicius Tragante, Andrej Teren, Jari Laurikka, Gerard Pasterkamp, Mahyar Heydarpour, Diederick E. Grobbee, Emil Hagström, Kenan Direk, Daniel Levin, Mika Kähönen, Riyaz S. Patel, Hooman Allayee, Yan Gong, A. Mark Richards, Simon C. Body, Michiel L. Bots, Graciela E. Delgado, Rhonda M. Cooper-DeHoff, Thomas O. Bergmeijer, John E. Deanfield, Ragnar O. Vilmundarson, Carl J. Pepine, Julie A. Johnson, Folkert W. Asselbergs, Markus Scholz, Ralph Burkhardt, Pekka Kuukasjärvi, Olaf H. Klungel, Anke H. Maitland-van der Zee, Jochen D. Muehlschlegel, Colin N. A. Palmer, Sander W. van der Laan, Christopher P. Nelson, G. Kees Hovingh, Joachim Thiery, Jessica van Setten, Stefan James, Raymond O McCubrey, Niclas Eriksson, Stanley L. Hazen, Laurence J. Howe, John A. Spertus, Terho Lehtimäki, Salma Kotti, Robert N. Doughty, Vicky A. Cameron, Axel Åkerblom, Marcin P. Kaczor, Peter S. Braund, Petra A. Lenzini, Sharon Cresci, Lars Wallentin, Marek Sanak, Adriaan O. Kraaijeveld, Jurriën M. ten Berg, Amand F. Schmidt, Leo-Pekka Lyytikäinen
Publikováno v:
Circulation, 142, 6, pp. 546-555
Circulation
Circulation, 142(6), 546-555. Lippincott Williams and Wilkins
Circulation, 142, 546-555
Circulation, 142(6), 546. Lippincott Williams and Wilkins
Circulation
Circulation, 142(6), 546-555. Lippincott Williams and Wilkins
Circulation, 142, 546-555
Circulation, 142(6), 546. Lippincott Williams and Wilkins
Background: Studies examining the role of factor V Leiden among patients at higher risk of atherothrombotic events, such as those with established coronary heart disease (CHD), are lacking. Given that coagulation is involved in the thrombus formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d37d30fb60ce0533239c3550d4c0acf
https://repository.ubn.ru.nl/handle/2066/235380
https://repository.ubn.ru.nl/handle/2066/235380
Autor:
Seyed Hamidreza Mahmoudpour, Ekaterina V Baranova, Anthonius de Boer, Patrick C. Souverein, Folkert W. Asselbergs, Anke-Hilse Maitland-van der Zee
Publikováno v:
British Journal of Clinical Pharmacology. 82:1647-1659
AIM: The aim of the present study was to describe the occurrence and determinants of angiotensin-converting enzyme (ACE) inhibitor (ACEI) intolerance and angioedema (AE) among patients initiating ACEI therapy in a real-world primary care population.
Autor:
Chris Finan, Yoav Ben-Shlomo, Eric B. Larson, Tine Jess, Richard W Morris, Daniel I. Chasman, Fernando Pires Hartwig, Catherine Welch, Rodney J. Scott, Helen E. Speedy, Andrzej Pajak, Raha Pazoki, André G. Uitterlinden, Torben Hansen, Marc Sanson, Hakon Hakonarson, Claudia Langenberg, Joey Ward, John Wright, Dorothée Thuillier, Ben Kinnersley, Diederick E. Grobbee, Yvonne T. van der Schouw, Pieter Sonneveld, Michiel L. Bots, Harold Snieder, Karim Labreche, Dan M. Roden, Archie Campbell, Melissa C. Smart, Christine Power, Pim van der Harst, Amélie Bonnefond, Ingrid E. Christophersen, Riyaz S. Patel, Uwe Völker, Stephen Hancock, Niels Grarup, Dennis O. Mook-Kanamori, Mariza de Andrade, Caroline Dale, N. Charlotte Onland-Moret, David R. Crosslin, Meena Kumari, Erik Ingelsson, Michael V. Holmes, Spiros Denaxas, Sudha Seshadri, Kees Hovingh, Marcus Dörr, Paul M. Ridker, Stefan Coassin, Albert Hofman, Andrew N. Nicolaides, Oluf Pedersen, Philippe Froguel, Simonetta Guarrera, Murray H. Brilliant, Sara E. Dobbins, Salim Yusuf, Kari Hemminki, Erik P A Van Iperen, Abbas Dehghan, Jill P. Pell, Alexander Teumer, Peter W. Schofield, Aroon D. Hingorani, Dan Mason, Amand F. Schmidt, Rui Bebiano Da Providencia E Costa, James M. Allan, Leslie A. Lange, Niels Weinhold, Stefan Gustafsson, Jackie F. Price, Mika Kivimäki, Hynek Pikhart, Kirchner H. Lester, Lars Lind, Philip J. Law, Cara L. Carty, David Preiss, Richard S. Houlston, Robin Young, Tom W. Meade, Martin O'Donnell, Alexander P. Reiner, Ni Li, Oscar H. Franco, Zammy Fairhurst-Hunter, Ronan Roussel, Tim Christen, Ilja Demuth, David Carrell, Catherine A. McCarty, Juan P. Casas, Johann Willeit, Peter H. Whincup, Stela McLachlan, Adelaida Sanchez-Galvez, Hartmut Goldschmidt, Guillaume Paré, Harry Hemingway, Anubha Mahajan, Elisabeth Steinhagen-Thiessen, Elizabeth G. Holliday, Giuseppe Matullo, Henry Völzke, Ian Ford, Martin Bobak, Pedro Marques-Vidal, Bertrand Cariou, Bernardo L. Horta, Melissa L. Bondy, Goya Wanamethee, Naveed Sattar, Steve E. Humphries, Marylyn D. Ritchie, Kristina Norman, Carlotta Sacerdote, Giovanni Fiorito, Sebastian E. Baumeister, Amit Sud, Dennis Valentine, Andreas Engert, Juri Demuth, Rupert Faraway, Abdonas Tamosiunas, Andrie G. Panayiotou, Terrie Kitchner, Lars Bertram, Sandosh Padmanabhan, Sofia Malyutina, Anke H. Maitland-van der Zee, Alex J. Cornish, Joshua C. Denny, Jian'an Luan, Robert A. Scott, Daniel I. Swerdlow, John Attia, Karin Willeit, Gareth J. Morgan, Michael Chong, Ruben N. Eppinga, Elina Hyppönen, Ekaterina V. Baranova, Jackie A. Cooper, Ghazaleh Fatemifar, Niek Verweij, Max Moldovan, Brendan J. Keating, M. Abdullah Said, Markus M. Lerch, Christina M. Lill, Markus Hansson, Jemma C. Hopewell, Björn Nilsson, Folkert W. Asselbergs, Ruzena Kubinova, Molly Went, Nicholas J. Wareham, Stefan Kiechl, Yanchun Bao, Allan Linneberg, Matthias Simon
Publikováno v:
BMC Cardiovascular Disorders, 19(1). BMC
Schmidt, Amand F; Holmes, Michael V; Preiss, David; Swerdlow, Daniel I; Denaxas, Spiros; Fatemifar, Ghazaleh; Faraway, Rupert; Finan, Chris; Valentine, Dennis; Fairhurst-Hunter, Zammy; Hartwig, Fernando Pires; Horta, Bernardo Lessa; Hypponen, Elina; Power, Christine; Moldovan, Max; van Iperen, Erik; Hovingh, Kees; Demuth, Ilja; Norman, Kristina; Steinhagen-Thiessen, Elisabeth; ... (2019). Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. BMC cardiovascular disorders, 19(1), p. 240. BioMed Central 10.1186/s12872-019-1187-z
BMC cardiovascular disorders, 19(1):240. BioMed Central
BMC cardiovascular disorders, London : BioMed Central, 2019, vol. 19, no. 1, 240, p. 1-10
BMC Cardiovascular Disorders
BMC Cardiovascular Disorders, 19(1). BioMed Central
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-10 (2019)
Schmidt, A F, Holmes, M V, Preiss, D, Swerdlow, D I, Denaxas, S, Fatemifar, G, Faraway, R, Finan, C, Valentine, D, Fairhurst-Hunter, Z, McLachlan, S & Price, J 2019, ' Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 ', Bmc cardiovascular disorders . https://doi.org/10.1186/s12872-019-1187-z
BMC Cardiovascular Disorders, 19(1):240. BioMed Central Ltd.
Schmidt, A F, Holmes, M V, Preiss, D, Swerdlow, D I, Denaxas, S, Fatemifar, G, Faraway, R, Finan, C, Valentine, D, Fairhurst-Hunter, Z, Hartwig, F P, Horta, B L, Hypponen, E, Power, C, Moldovan, M, Van Iperen, E, Hovingh, K, Demuth, I, Norman, K, Steinhagen-Thiessen, E, Demuth, J, Bertram, L, Lill, C M, Coassin, S, Willeit, J, Kiechl, S, Willeit, K, Mason, D, Wright, J, Morris, R, Wanamethee, G, Whincup, P, Ben-Shlomo, Y, McLachlan, S, Price, J F, Kivimaki, M, Welch, C, Sanchez-Galvez, A, Marques-Vidal, P, Nicolaides, A, Panayiotou, A G, Onland-Moret, N C, Van Der Schouw, Y T, Matullo, G, Fiorito, G, Guarrera, S, Sacerdote, C, Wareham, N J, Langenberg, C, Scott, R A, Luan, JA, Bobak, M, Malyutina, S, Pajak, A, Kubinova, R, Tamosiunas, A, Pikhart, H, Grarup, N, Pedersen, O, Hansen, T, Linneberg, A, Jess, T, Cooper, J, Humphries, S E, Brilliant, M, Kitchner, T, Hakonarson, H, Carrell, D S, McCarty, C A, Lester, K H, Larson, E B, Crosslin, D R, De Andrade, M, Roden, D M, Denny, J C, Carty, C, Hancock, S, Attia, J, Holliday, E, Scott, R, Schofield, P, O'Donnell, M, Yusuf, S, Chong, M, Pare, G, Van Der Harst, P, Said, M A, Eppinga, R N, Verweij, N, Snieder, H, Christen, T, Mook-Kanamori, D O, Gustafsson, S, Lind, L, Ingelsson, E, Pazoki, R, Franco, O, Hofman, A, Uitterlinden, A, Dehghan, A, Teumer, A, Baumeister, S, Dörr, M, Lerch, M M, Völker, U, Völzke, H, Ward, J, Pell, J P, Meade, T, Christophersen, I E, Maitland-Van Der Zee, A H, Baranova, E V, Young, R, Ford, I, Campbell, A, Padmanabhan, S, Bots, M L, Grobbee, D E, Froguel, P, Thuillier, D, Roussel, R, Bonnefond, A, Cariou, B, Smart, M, Bao, Y, Kumari, M, Mahajan, A, Hopewell, J C, Seshadri, S, Dale, C, Costa, R P E, Ridker, P M, Chasman, D I, Reiner, A P, Ritchie, M D, Lange, L A, Cornish, A J, Dobbins, S E, Hemminki, K, Kinnersley, B, Sanson, M, Labreche, K, Simon, M, Bondy, M, Law, P, Speedy, H, Allan, J, Li, N, Went, M, Weinhold, N, Morgan, G, Sonneveld, P, Nilsson, B, Goldschmidt, H, Sud, A, Engert, A, Hansson, M, Hemingway, H, Asselbergs, F W, Patel, R S, Keating, B J, Sattar, N, Houlston, R, Casas, J P & Hingorani, A D 2019, ' Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 ', BMC Cardiovascular Disorders, vol. 19, no. 1, 240 . https://doi.org/10.1186/s12872-019-1187-z
Schmidt, Amand F; Holmes, Michael V; Preiss, David; Swerdlow, Daniel I; Denaxas, Spiros; Fatemifar, Ghazaleh; Faraway, Rupert; Finan, Chris; Valentine, Dennis; Fairhurst-Hunter, Zammy; Hartwig, Fernando Pires; Horta, Bernardo Lessa; Hypponen, Elina; Power, Christine; Moldovan, Max; van Iperen, Erik; Hovingh, Kees; Demuth, Ilja; Norman, Kristina; Steinhagen-Thiessen, Elisabeth; ... (2019). Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. BMC cardiovascular disorders, 19(1), p. 240. BioMed Central 10.1186/s12872-019-1187-z
BMC cardiovascular disorders, 19(1):240. BioMed Central
BMC cardiovascular disorders, London : BioMed Central, 2019, vol. 19, no. 1, 240, p. 1-10
BMC Cardiovascular Disorders
BMC Cardiovascular Disorders, 19(1). BioMed Central
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-10 (2019)
Schmidt, A F, Holmes, M V, Preiss, D, Swerdlow, D I, Denaxas, S, Fatemifar, G, Faraway, R, Finan, C, Valentine, D, Fairhurst-Hunter, Z, McLachlan, S & Price, J 2019, ' Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 ', Bmc cardiovascular disorders . https://doi.org/10.1186/s12872-019-1187-z
BMC Cardiovascular Disorders, 19(1):240. BioMed Central Ltd.
Schmidt, A F, Holmes, M V, Preiss, D, Swerdlow, D I, Denaxas, S, Fatemifar, G, Faraway, R, Finan, C, Valentine, D, Fairhurst-Hunter, Z, Hartwig, F P, Horta, B L, Hypponen, E, Power, C, Moldovan, M, Van Iperen, E, Hovingh, K, Demuth, I, Norman, K, Steinhagen-Thiessen, E, Demuth, J, Bertram, L, Lill, C M, Coassin, S, Willeit, J, Kiechl, S, Willeit, K, Mason, D, Wright, J, Morris, R, Wanamethee, G, Whincup, P, Ben-Shlomo, Y, McLachlan, S, Price, J F, Kivimaki, M, Welch, C, Sanchez-Galvez, A, Marques-Vidal, P, Nicolaides, A, Panayiotou, A G, Onland-Moret, N C, Van Der Schouw, Y T, Matullo, G, Fiorito, G, Guarrera, S, Sacerdote, C, Wareham, N J, Langenberg, C, Scott, R A, Luan, JA, Bobak, M, Malyutina, S, Pajak, A, Kubinova, R, Tamosiunas, A, Pikhart, H, Grarup, N, Pedersen, O, Hansen, T, Linneberg, A, Jess, T, Cooper, J, Humphries, S E, Brilliant, M, Kitchner, T, Hakonarson, H, Carrell, D S, McCarty, C A, Lester, K H, Larson, E B, Crosslin, D R, De Andrade, M, Roden, D M, Denny, J C, Carty, C, Hancock, S, Attia, J, Holliday, E, Scott, R, Schofield, P, O'Donnell, M, Yusuf, S, Chong, M, Pare, G, Van Der Harst, P, Said, M A, Eppinga, R N, Verweij, N, Snieder, H, Christen, T, Mook-Kanamori, D O, Gustafsson, S, Lind, L, Ingelsson, E, Pazoki, R, Franco, O, Hofman, A, Uitterlinden, A, Dehghan, A, Teumer, A, Baumeister, S, Dörr, M, Lerch, M M, Völker, U, Völzke, H, Ward, J, Pell, J P, Meade, T, Christophersen, I E, Maitland-Van Der Zee, A H, Baranova, E V, Young, R, Ford, I, Campbell, A, Padmanabhan, S, Bots, M L, Grobbee, D E, Froguel, P, Thuillier, D, Roussel, R, Bonnefond, A, Cariou, B, Smart, M, Bao, Y, Kumari, M, Mahajan, A, Hopewell, J C, Seshadri, S, Dale, C, Costa, R P E, Ridker, P M, Chasman, D I, Reiner, A P, Ritchie, M D, Lange, L A, Cornish, A J, Dobbins, S E, Hemminki, K, Kinnersley, B, Sanson, M, Labreche, K, Simon, M, Bondy, M, Law, P, Speedy, H, Allan, J, Li, N, Went, M, Weinhold, N, Morgan, G, Sonneveld, P, Nilsson, B, Goldschmidt, H, Sud, A, Engert, A, Hansson, M, Hemingway, H, Asselbergs, F W, Patel, R S, Keating, B J, Sattar, N, Houlston, R, Casas, J P & Hingorani, A D 2019, ' Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 ', BMC Cardiovascular Disorders, vol. 19, no. 1, 240 . https://doi.org/10.1186/s12872-019-1187-z
BackgroundWe characterised the phenotypic consequence of genetic variation at the PCSK9 locus and compared findings with recent trials of pharmacological inhibitors of PCSK9.MethodsPublished and individual participant level data (300,000+ participant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8a7b3e5163aceb6019624e27507e6b
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-401186
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-401186
Autor:
Ekaterina V Baranova, Anthonius de Boer, Anke-Hilse Maitland-van der Zee, Talitha I. Verhoef, Folkert W. Asselbergs
Publikováno v:
Expert Opinion on Drug Metabolism and Toxicology, 11(4), 509. Informa Healthcare
INTRODUCTION: A large proportion of the coumarin dose variability is explained by environmental factors and by common genetic variants in the VKORC1 and CYP2C9 genes. Genotype-guided coumarin dosing has been proposed for a more accurate prediction of
Autor:
Yi-Juan Hu, Amand F. Schmidt, Frank Dudbridge, Michael V. Holmes, James M. Brophy, Vinicius Tragante, Ziyi Li, Peizhou Liao, Arshed A. Quyyumi, Raymond O. McCubrey, Benjamin D. Horne, Aroon D. Hingorani, Folkert W. Asselbergs, Riyaz S. Patel, Qi Long, Axel Åkerblom, Ale Algra, Hooman Allayee, Peter Almgren, Jeffrey L. Anderson, Maria G. Andreassi, Chiara V. Anselmi, Diego Ardissino, Benoit J. Arsenault, Christie M. Ballantyne, Ekaterina V. Baranova, Hassan Behloui, Thomas O. Bergmeijer, Connie R. Bezzina, Eythor Bjornsson, Simon C. Body, Bram Boeckx, Eric (H.) Boersma, Eric Boerwinkle, Peter Bogaty, Peter S. Braund, Lutz P. Breitling, Hermann Brenner, Carlo Briguori, Jasper J. Brugts, Ralph Burkhardt, Vicky A. Cameron, John F. Carlquist, Clara Carpeggiani, Kathryn F. Carruthers, Gavino Casu, Gianluigi Condorelli, Sharon Cresci, Nicolas Danchin, Ulf de Faire, John Deanfield, Graciela Delgado, Panos Deloukas, Kenan Direk, Robert N. Doughty, Heinz Drexel, Nubia E. Duarte, Marie-Pierre Dubé, Line Dufresne, James C. Engert, Niclas Eriksson, Natalie Fitzpatrick, Luisa Foco, Ian Ford, Keith A.A. Fox, Bruna Gigante, Crystel M. Gijsberts, Domenico Girelli, Yan Gong, Daniel F. Gudbjartsson, Emil Hagström, Jaana Hartiala, Stanley L. Hazen, Claes Held, Anna Helgadottir, Harry Hemingway, Mahyar Heydarpour, Imo E. Hoefer, Kees Hovingh, Jaroslav A. Hubacek, Stefan James, Julie A. Johnson, J. Wouter Jukema, Marcin P. Kaczor, Karol A. Kaminski, Jiri Kettner, Marek Kiliszek, Marcus Kleber, Olaf H. Klungel, Daniel Kofink, Mika Kohonen, Salma Kotti, Pekka Kuukasjärvi, Bo Lagerqvist, Diether Lambrechts, Chim C. Lang, Jari O. Laurikka, Karin Leander, Vei-Vei Lee, Terho Lehtimäki, Andreas Leiherer, Petra A. Lenzini, Daniel Levin, Daniel Lindholm, Marja-Liisa Lokki, Paulo A. Lotufo, Leo-Pekka Lyytikäinen, B. Khan Mahmoodi, Anke H. Maitland-van der Zee, Nicola Martinelli, Winfried März, Nicola Marziliano, Ruth McPherson, Olle Melander, Ute Mons, Jochen D. Muehlschlegel, Joseph B. Muhlestein, Cristopher P. Nelson, Chris Newton Cheh, Oliviero Olivieri, Grzegorz Opolski, Colin N. Palmer, Guillaume Pare, Gerard Pasterkamp, Carl J. Pepine, Witold Pepinski, Alexandre C. Pereira, Anna P. Pilbrow, Louise Pilote, Jan Pitha, Rafal Ploski, A. Mark Richards, Christoph H. Saely, Nilesh J. Samani, Ayman Samman-Tahhan, Marek Sanak, Pratik B. Sandesara, Naveed Sattar, Markus Scholz, Agneta Siegbahn, Tabassome Simon, Juha Sinisalo, J. Gustav Smith, John A. Spertus, Kari Stefansson, Alexandre F.R. Stewart, David J. Stott, Wojciech Szczeklik, Anna Szpakowicz, Michael W.T. Tanck, Wilson H. Tang, Jean-Claude Tardif, Jur M. ten Berg, Andrej Teren, George Thanassoulis, Joachim Thiery, Gudmundur Thorgeirsson, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Adam Timmis, Stella Trompet, Frans van de Werf, Yolanda van der Graaf, Pim van der Haarst, Sander W. van der Laan, Ragnar O. Vilmundarson, Salim S. Virani, Frank L.J. Visseren, Efthymia Vlachopoulou, Lars Wallentin, Johannes Waltenberger, Els Wauters, Arthur A.M. Wilde
Publikováno v:
Circulation: Cardiovascular Genetics, 10(5):e001616. Lippincott Williams & Wilkins
Circulation-Cardiovascular genetics, 10(5). Lippincott Williams and Wilkins
Circulation-Cardiovascular Genetics, 10(5):e001616. LIPPINCOTT WILLIAMS & WILKINS
Circulation: Cardiovascular Genetics, 10(5):e001616. Lippincott Williams and Wilkins
Circulation: Cardiovascular Genetics, 10(5). Lippincott Williams and Wilkins
Circulation-Cardiovascular genetics, 10(5). Lippincott Williams and Wilkins
Circulation-Cardiovascular Genetics, 10(5):e001616. LIPPINCOTT WILLIAMS & WILKINS
Circulation: Cardiovascular Genetics, 10(5):e001616. Lippincott Williams and Wilkins
Circulation: Cardiovascular Genetics, 10(5). Lippincott Williams and Wilkins
Background— Studies of recurrent or subsequent disease events may be susceptible to bias caused by selection of subjects who both experience and survive the primary indexing event. Currently, the magnitude of any selection bias, particularly for su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1454386493a8522ffca7767d1923d2f4
https://europepmc.org/articles/PMC5659743/
https://europepmc.org/articles/PMC5659743/
Publikováno v:
Current Molecular Medicine. 14:841-848
Coumarin derivates are oral anticoagulants commonly prescribed for treatment and prevention of thromboembolism. Due to a small therapeutic index and large inter- and intrapatient differences in dose requirements, treatment with coumarins is challengi
Autor:
Ekaterina V Baranova, Patrick C. Souverein, Folkert W. Asselbergs, A Maitland-van der Zee, Seyed Hamidreza Mahmoudpour, A. de Boer
Publikováno v:
Value in Health. 19(3)
Objectives: This study describes the occurrence of angioedema among patients initiating ACEI therapy and evaluates the association of this outcome with demographic factors, co-medication and chronic comorbidities. Methods: A nested case-control study
Autor:
J. Francis Borgio, Mohammed Fakhry Ibrahim, Mohammed Almansori, Ekaterina V Baranova, Rudaynah A. Alali, Abdullah M. Alshehri, Bobby P. C. Koeleman, Abdullah Al-Ali, Mohammed S. Al-Madan, Fahad Al-Muhanna, Awatif N. Al-Nafie, Sayed AbdulAzeez, Amein K. Al-Ali, Folkert W. Asselbergs, Brendan J. Keating
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 3, p 395 (2016)
International Journal of Molecular Sciences; Volume 17; Issue 3; Pages: 395
International Journal of Molecular Sciences
International journal of molecular sciences, 17(3). Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences; Volume 17; Issue 3; Pages: 395
International Journal of Molecular Sciences
International journal of molecular sciences, 17(3). Multidisciplinary Digital Publishing Institute (MDPI)
Recent genome-wide association studies identified single nucleotide polymorphisms (SNPs) on the chromosome 9p21.3 conferring the risk for CAD (coronary artery disease) in individuals of Caucasian ancestry. We performed a genetic association study to