E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidation

Autor: Keerthiraju E Ravichandran, Lars Kaduhr, Bozena Skupien‐Rabian, Ekaterina Shvetsova, Mikołaj Sokołowski, Ros´cisław Krutyhołowa, Dominika Kwasna, Cindy Brachmann, Sean Lin, Sebastian Guzman Perez, Piotr Wilk, Manuel Kösters, Przemysław Grudnik, Urszula Jankowska, Sebastian A Leidel, Raffael Schaffrath, Sebastian Glatt

Publikováno v: Ravichandran, Keerthiraju E; Kaduhr, Lars; Skupien-Rabian, Bozena; Shvetsova, Ekaterina; Sokołowski, Mikołaj; Krutyhołowa, Ros Cisław; Kwasna, Dominika; Brachmann, Cindy; Lin, Sean; Guzman Perez, Sebastian; Wilk, Piotr; Kösters, Manuel; Grudnik, Przemysław; Jankowska, Urszula; Leidel, Sebastian A; Schaffrath, Raffael; Glatt, Sebastian (2022). E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidation. The EMBO journal, 41(20), e111318. EMBO Press 10.15252/embj.2022111318

Post-translational modifications by ubiquitin-like proteins (UBLs) are essential for nearly all cellular processes. Ubiquitin-related modifier 1 (Urm1) is a unique UBL, which plays a key role in tRNA anticodon thiolation as a sulfur carrier protein (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743dd75f630b383ea5758a3f19ace983

Mouse Trmt2B protein is a dual specific mitochondrial metyltransferase responsible for m5U formation in both tRNA and rRNA

Autor: Petr V. Sergiev, Marina V. Serebryakova, Ekaterina Shvetsova, Piotr Kamenski, Olga A. Dontsova, S. A. Levitskii, M. P. Rubtsova, I. G. Laptev, Alexey A. Bogdanov

Publikováno v: RNA Biol

RNA molecules of all species contain modified nucleotides and particularly m(5)U residues. The vertebrate mitochondrial small subunit rRNA contains m(5)U nucleotide in a unique site. In this work we found an enzyme, TRMT2B, responsible for the format

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca437e03c16d7a61b5cb72eb85829ad5
https://doi.org/10.1080/15476286.2019.1694733

Ncs2* mediates in vivo virulence of pathogenic yeast through sulphur modification of cytoplasmic transfer RNA.

Autor: Alings, Fiona, Scharmann, Karin, Eggers, Cristian, Böttcher, Bettina, Sokołowski, Mikołaj, Shvetsova, Ekaterina, Sharma, Puneet, Roth, Joël, Rashiti, Leon, Glatt, Sebastian, Brunke, Sascha, Leidel, Sebastian A

Publikováno v: Nucleic Acids Research; 8/25/2023, Vol. 51 Issue 15, p8133-8149, 17p

METTL15 interacts with the assembly intermediate of murine mitochondrial small ribosomal subunit to form m⁴C840 12S rRNA residue.

Autor: Laptev, Ivan, Shvetsova, Ekaterina, Levitskii, Sergey, Serebryakova, Marina, Rubtsova, Maria, Zgoda, Victor, Bogdanov, Alexey, Kamenski, Piotr, Sergiev, Petr, Dontsova, Olga

Publikováno v: Nucleic Acids Research; 8/20/2020, Vol. 48 Issue 14, p8022-8034, 13p