Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ekaterina Round"'
Autor:
Clement E. Blanchet, Adam Round, Haydyn D. T. Mertens, Kartik Ayyer, Melissa Graewert, Salah Awel, Daniel Franke, Katerina Dörner, Saša Bajt, Richard Bean, Tânia F. Custódio, Raphael de Wijn, E. Juncheng, Alessandra Henkel, Andrey Gruzinov, Cy M. Jeffries, Yoonhee Kim, Henry Kirkwood, Marco Kloos, Juraj Knoška, Jayanath Koliyadu, Romain Letrun, Christian Löw, Jana Makroczyova, Abhishek Mall, Rob Meijers, Gisel Esperanza Pena Murillo, Dominik Oberthür, Ekaterina Round, Carolin Seuring, Marcin Sikorski, Patrik Vagovic, Joana Valerio, Tamme Wollweber, Yulong Zhuang, Joachim Schulz, Heinrich Haas, Henry N. Chapman, Adrian P. Mancuso, Dmitri Svergun
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Free-electron lasers (FEL) are revolutionizing X-ray-based structural biology methods. While protein crystallography is already routinely performed at FELs, Small Angle X-ray Scattering (SAXS) studies of biological macromolecules are not as
Externí odkaz:
https://doaj.org/article/bcf514c39af3436883cc2c8e5bf81aab
Autor:
Dmitrii Zabelskii, Natalia Dmitrieva, Oleksandr Volkov, Vitaly Shevchenko, Kirill Kovalev, Taras Balandin, Dmytro Soloviov, Roman Astashkin, Egor Zinovev, Alexey Alekseev, Ekaterina Round, Vitaly Polovinkin, Igor Chizhov, Andrey Rogachev, Ivan Okhrimenko, Valentin Borshchevskiy, Vladimir Chupin, Georg Büldt, Natalia Yutin, Ernst Bamberg, Eugene Koonin, Valentin Gordeliy
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Zabelskii et al. present a structural and functional analysis of the lightdriven proton pump LR (Mac) from the fungus Leptosphaeria maculans. Their findings indicate that the archaeal ancestry of eukaryotic type 1 rhodopsins, and that the archaeal ho
Externí odkaz:
https://doaj.org/article/ffd8f8139a3d4a9c8b6afe6dc044007f
Autor:
Dmitry Bratanov, Taras Balandin, Ekaterina Round, Vitaly Shevchenko, Ivan Gushchin, Vitaly Polovinkin, Valentin Borshchevskiy, Valentin Gordeliy
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128390 (2015)
Heterologous overexpression of functional membrane proteins is a major bottleneck of structural biology. Bacteriorhodopsin from Halobium salinarum (bR) is a striking example of the difficulties in membrane protein overexpression. We suggest a general
Externí odkaz:
https://doaj.org/article/8e322458e268483fa2d3b018ad8164b1
Autor:
Valentin Borshchevskiy, Ekaterina Round, Yulia Bertsova, Vitaly Polovinkin, Ivan Gushchin, Andrii Ishchenko, Kirill Kovalev, Alexey Mishin, Galina Kachalova, Alexander Popov, Alexander Bogachev, Valentin Gordeliy
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118548 (2015)
Na+-translocating NADH:quinone oxidoreductase (NQR) is a redox-driven sodium pump operating in the respiratory chain of various bacteria, including pathogenic species. The enzyme has a unique set of redox active prosthetic groups, which includes two
Externí odkaz:
https://doaj.org/article/f352ddcc21aa4a39b3d46f7f3ac5c67b
Autor:
Vitaly Shevchenko, Ivan Gushchin, Vitaly Polovinkin, Ekaterina Round, Valentin Borshchevskiy, Petr Utrobin, Alexander Popov, Taras Balandin, Georg Büldt, Valentin Gordeliy
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e112873 (2014)
Bacteriorhodopsins are a large family of seven-helical transmembrane proteins that function as light-driven proton pumps. Here, we present the crystal structure of a new member of the family, Haloarcula marismortui bacteriorhodopsin I (HmBRI) D94N mu
Externí odkaz:
https://doaj.org/article/94b754aa625b4cd29d657acb08d19290
Autor:
Mohammad Vakili, Huijong Han, Christina Schmidt, Agnieszka Wrona, Marco Kloos, Iñaki de Diego, Katerina Dörner, Tian Geng, Chan Kim, Faisal Koua, Diogo Melo, Mathieu Rappas, Adam Round, Ekaterina Round, Marcin Sikorski, Joana Valerio, Tiankun Zhou, Kristina Lorenzen, Joachim Schulz
Time-resolved crystallography enabled the visualization of protein molecular motion during reaction. While light is commonly used to initiate reactions in time-resolved crystallography, only a small number of proteins can in fact be activated by ligh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77a6c80d46f30382cc1ce84be0368a47
https://doi.org/10.1101/2022.11.23.517685
https://doi.org/10.1101/2022.11.23.517685
Autor:
Domingo Meza, Philipp Heuser, Kristina Lorenzen, Petra Fromme, Joachim Schulz, Yasmin Gül, Christian Betzel, Huijong Han, Poul Nissen, Victor S. Lamzin, Janos Hajdu, Robin Schubert, Inari Kursula, Jozef Ulicný, Matthias Wilmanns, Jana Makroczyová, Martin Aepfelbacher, Elena Tereschenko, Ekaterina Round, Charlotte Uetrecht, Imrich Barák
Publikováno v:
Journal of Applied Crystallography
Han, H, Round, E, Schubert, R, Gül, Y, Makroczyová, J, Meza, D, Heuser, P, Aepfelbacher, M, Barák, I, Betzel, C, Fromme, P, Kursula, I, Nissen, P, Tereschenko, E, Schulz, J, Uetrecht, C, Ulicný, J, Wilmanns, M, Hajdu, J, Lamzin, V S & Lorenzen, K 2021, ' The XBI BioLab for life science experiments at the European XFEL ', Journal of Applied Crystallography, vol. 54, no. Part 1, pp. 7-21 . https://doi.org/10.1107/S1600576720013989
Han, H, Round, E, Schubert, R, Gül, Y, Makroczyová, J, Meza, D, Heuser, P, Aepfelbacher, M, Barák, I, Betzel, C, Fromme, P, Kursula, I, Nissen, P, Tereschenko, E, Schulz, J, Uetrecht, C, Ulicný, J, Wilmanns, M, Hajdu, J, Lamzin, V S & Lorenzen, K 2021, ' The XBI BioLab for life science experiments at the European XFEL ', Journal of Applied Crystallography, vol. 54, no. Part 1, pp. 7-21 . https://doi.org/10.1107/S1600576720013989
An overview of a unique life science facility at the European XFEL is provided, and its importance in sample preparation, characterization and analysis prior to measurements at the different European XFEL instruments is discussed. The capabilities th
Autor:
Valentin Borshchevskiy, Kirill Kovalev, Ekaterina Round, Rouslan Efremov, Roman Astashkin, Gleb Bourenkov, Dmitry Bratanov, Taras Balandin, Igor Chizhov, Christian Baeken, Ivan Gushchin, Alexander Kuzmin, Alexey Alekseev, Andrey Rogachev, Dieter Willbold, Martin Engelhard, Ernst Bamberg, Georg Büldt, Valentin Gordeliy
Publikováno v:
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2022, 29 (5), pp.440-450. ⟨10.1038/s41594-022-00762-2⟩
Nature Structural and Molecular Biology, 2022, 29 (5), pp.440-450. ⟨10.1038/s41594-022-00762-2⟩
International audience; Hydrogen bonds are fundamental to the structure and function of biological macromolecules and have been explored in detail. The chains of hydrogen bonds (CHBs) and low-barrier hydrogen bonds (LBHBs) were proposed to play essen
Autor:
Alexey A. Belogurov, Spyros D. Chatziefthimiou, Richard A. Lerner, Ekaterina Round, Yuliana A. Mokrushina, T. V. Bobik, Alexander G. Gabibov, Anastasia V. Stepanova, Andrey V. Golovin, G. Michael Blackburn, Gleb Bourenkov, Matthias Wilmanns, Alexander Zlobin, O. G. Shamborant, Ivan V. Smirnov, Alexey Stepanov, Kirill A. Konovalov, Arthur O. Zalevsky, Stanislav S. Terekhov, Sofiya O. Pipiya, Jia Xie, Alexander A. Makarov
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 117(37), 22841-22848 (2020). doi:10.1073/pnas.2010317117
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America 117(37), 22841 - 22848 (2020). doi:10.1073/pnas.2010317117
Quantum mechanics/molecular mechanics (QM/MM) maturation of an immunoglobulin (Ig) powered by supercomputa
Quantum mechanics/molecular mechanics (QM/MM) maturation of an immunoglobulin (Ig) powered by supercomputa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8487a01b9207d346e1a8894bad052d84
Autor:
Vadim Cherezov, Andrey Bogorodskiy, Georg Büldt, Vitaly Polovinkin, Alexey Mishin, Fedor Frolov, Valentin Gordeliy, Valentin Borshchevskiy, Thomas Gensch, Ekaterina Round
Publikováno v:
Crystal Growth & Design. 15:5656-5660
Since the introduction of in meso crystallization of membrane proteins in lipidic cubic phase (LCP) by Landau and Rosenbusch in 1996, numerous studies attempted to elucidate the mechanism of in meso crystal nucleation and growth. Here we present a fl