Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ekaterina Poverennaya"'
Autor:
Daniil Romashin, Alexander Rusanov, Viktoriia Arzumanian, Alexandra Varshaver, Ekaterina Poverennaya, Igor Vakhrushev, Alexander Netrusov, Nataliya Luzgina
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 2, Pp 1451-1466 (2024)
Approximately 50% of tumors carry mutations in TP53; thus, evaluation of the features of mutant p53 is crucial to understanding the mechanisms underlying cell transformation and tumor progression. HaCaT keratinocytes represent a valuable model for re
Externí odkaz:
https://doaj.org/article/c2022e7271e447cf9375a615055744fd
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10065 (2023)
Over the past 8 years, multiple studies examined the phenomenon of isoform switching in human cancers and discovered that isoform switching is widespread, with hundreds to thousands of such events per cancer type. Although all of these studies used s
Externí odkaz:
https://doaj.org/article/d2173788e12548e999d557981211d755
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8791 (2023)
Background: Comparative transcriptomic analysis is a powerful approach for investigating the molecular mechanisms underlying various physiological and pathological processes, including liver disease. The liver is a vital organ with diverse functions,
Externí odkaz:
https://doaj.org/article/e35f38d6232f4aeebcbdc917bbe870b5
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 4155 (2023)
Increasing attention has been focused on the study of protein–metabolite interactions (PMI), which play a key role in regulating protein functions and directing an orchestra of cellular processes. The investigation of PMIs is complicated by the fac
Externí odkaz:
https://doaj.org/article/55b1091f72ec45cb851fed5f34dfa9e8
Publikováno v:
Metabolites, Vol 13, Iss 1, p 75 (2023)
Metabolomics based on two-dimensional gas chromatography coupled with mass spectrometry is making high demands on accuracy at all stages of sample preparation, up to the storage and injection into the analytical system. In high sample flow conditions
Externí odkaz:
https://doaj.org/article/350a0337671948ebbe44698036957a30
Autor:
Ekaterina Ilgisonis, Nikita Vavilov, Elena Ponomarenko, Andrey Lisitsa, Ekaterina Poverennaya, Victor Zgoda, Sergey Radko, Alexander Archakov
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The cutoff level applied in sequencing analysis varies according to the sequencing technology, sample type, and study purpose, which can largely affect the coverage and reliability of the data obtained. In this study, we aimed to determine the optima
Externí odkaz:
https://doaj.org/article/d989aa47c3c84d468c69778966ec392c
Publikováno v:
Metabolites, Vol 12, Iss 1, p 15 (2021)
Metabolomics uses advanced analytical chemistry methods to analyze metabolites in biological samples. The most intensively studied samples are blood and its liquid components: plasma and serum. Armed with advanced equipment and progressive software s
Externí odkaz:
https://doaj.org/article/9248e3b58ccc4c9eae95fab137309273
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 3813 (2020)
One of the major goals of the Chromosome-Centric Human Proteome Project (C-HPP) is to catalog and annotate a myriad of heterogeneous proteoforms, produced by ca. 20 thousand genes. To achieve a detailed and personalized understanding into proteomes,
Externí odkaz:
https://doaj.org/article/f695ade779a4456fab0102c62514d15e
Autor:
Ekaterina Poverennaya, Olga Kiseleva, Ekaterina Ilgisonis, Svetlana Novikova, Arthur Kopylov, Yuri Ivanov, Alexei Kononikhin, Mikhail Gorshkov, Nikolay Kushlinskii, Alexander Archakov, Elena Ponomarenko
Publikováno v:
Proteomes, Vol 8, Iss 2, p 12 (2020)
Despite direct or indirect efforts of the proteomic community, the fraction of blind spots on the protein map is still significant. Almost 11% of human genes encode missing proteins; the existence of which proteins is still in doubt. Apparently, prot
Externí odkaz:
https://doaj.org/article/3d97296f9118449c8b320f7e5ed4ebbd
Autor:
Mikhail Pyatnitskiy, Dmitriy Karpov, Ekaterina Poverennaya, Andrey Lisitsa, Sergei Moshkovskii
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142819 (2015)
We propose an approach to detection of essential genes/proteins required for cancer cell survival. A gene is considered essential if a mutation with high impact upon the function of encoded protein causes death of the cancer cell. We draw an analogy
Externí odkaz:
https://doaj.org/article/621deab78f324cd6bad9f3a6202c929a