Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ekaterina P. Mochalova"'
Autor:
Sergey A. Tyganov, Ekaterina P. Mochalova, Svetlana P. Belova, Kristina A. Sharlo, Sergey V. Rozhkov, Natalia A. Vilchinskaya, Inna I. Paramonova, Timur M. Mirzoev, Boris S. Shenkman
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
It is known that plantar mechanical stimulation (PMS) is able to attenuate unloading-induced skeletal muscle atrophy and impaired muscle function. However, molecular mechanisms underlying the effect of PMS on skeletal muscle during unloading remain u
Externí odkaz:
https://doaj.org/article/f78966b292b34363af1b1afd20075cea
Autor:
Kristina A. Sharlo, Inna I. Paramonova, Irina D. Lvova, Ekaterina P. Mochalova, Vitaliy E. Kalashnikov, Natalia A. Vilchinskaya, Sergey A. Tyganov, Tatyana S. Konstantinova, Tatiana F. Shevchenko, Grigoriy R. Kalamkarov, Boris S. Shenkman
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1372 (2021)
It was observed that gravitational unloading during space missions and simulated microgravity in ground-based studies leads to both transformation of slow-twitch muscle fibers into fast-twitch fibers and to the elimination of support afferentation, l
Externí odkaz:
https://doaj.org/article/cc3baaab69a84086a5b46d44872887a7
Autor:
Ekaterina P. Mochalova, Svetlana P. Belova, Tatiana Y. Kostrominova, Boris S. Shenkman, Tatiana L. Nemirovskaya
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 13, p 4815 (2020)
Unloading leads to skeletal muscle atrophy via the upregulation of MuRF-1 and MAFbx E3-ligases expression. Reportedly, histone deacetylases (HDACs) 4 and 5 may regulate the expression of MuRF1 and MAFbx. To examine the HDAC-dependent mechanisms invol
Externí odkaz:
https://doaj.org/article/72a9b3d6d61d448e9fcc4cc03b5821aa
Autor:
Svetlana P. Belova, Ekaterina P. Mochalova, Tatiana Y. Kostrominova, Boris S. Shenkman, Tatiana L. Nemirovskaya
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 2756 (2020)
To test the hypothesis that p38α-MAPK plays a critical role in the regulation of E3 ligase expression and skeletal muscle atrophy during unloading, we used VX-745, a selective p38α inhibitor. Three groups of rats were used: non-treated control (C),
Externí odkaz:
https://doaj.org/article/6879d4bcdc8a4bfbb28606b45b7cdae4
Autor:
Ekaterina A. Mochalova
Publikováno v:
Достоевский и мировая культура: Филологический журнал, Iss 1 (21), Pp 243-260 (2023)
In the tenth grade we read Dostoevsky’s novel Crime and Punishment, where several real-life places in St. Petersburg are described. Few names of these places are written in full; the very fact that the action takes place in a designated place indic
Externí odkaz:
https://doaj.org/article/06cd0bf91a7b459b97384e9078d005cb
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 57:720-729
Due to urbanization, automation and mechanization of labor, as well as difficult epidemiological situation and self-isolation, the level of daily physical activity in a modern man decreases. The aim of the study was to study the effect of restricted
Publikováno v:
Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 14:74-80
The role of histone deacetylases 4/5 (HDAC4/5) in the activation of myogenin and E3 ligases (MuRF1 and MAFbx) under functional unloading of m. soleus was studied. For this purpose, trichostatin A, a histone deacetylase inhibitor, was used in suspende
Autor:
Boris Shenkman, Natalia A. Vilchinskaya, S. P. Belova, Inna I. Paramonova, T. M. Mirzoev, Ekaterina P. Mochalova
Publikováno v:
Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 14:1-6
Molecular mechanisms initiating the development of atrophic changes in a mammalian postural muscle remain unclear. We have suggested that AMP-activated protein kinase (AMPK) may play an important role in the regulation of anabolic and catabolic signa
Autor:
Ivan M. Vikhlyantsev, Boris Shenkman, T. M. Mirzoev, Ekaterina P. Mochalova, Kristina A. Sharlo, Sergey Tyganov, Ivan Melnikov, A. D. Ulanova
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(10)
The study was aimed at investigating the mechanisms and structures which determine mechanical properties of skeletal muscles under gravitational unloading and plantar mechanical stimulation (PMS). We hypothesized that PMS would increase NO production
Autor:
Ekaterina P. Mochalova, Sergey Tyganov, Boris Shenkman, Kristina A. Sharlo, Grigoryi Kalamkarov, Inna I. Paramonova
Publikováno v:
NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY.