Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Ekaterina Muyzhnek"'
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A new promising way of maintenance therapy in advanced ovarian cancer: a comparative clinical study
Autor: Evgeniya V. Gerfanova, Fazlul H. Sarkar, Levon A. Ashrafyan, Olga I. Aleshikova, Ekaterina Muyzhnek, Vsevolod Kiselev, Irina B. Antonova
Publikováno v: BMC Cancer, Vol 18, Iss 1, Pp 1-16 (2018)
Background There is an urgent need for more novel and efficacious therapeutic agents and strategies for the treatment of ovarian cancer - one of the most formidable female malignancies. These approaches should be based on comprehensive understanding
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d215537336f932e68949bd50cf319aba
http://link.springer.com/article/10.1186/s12885-018-4792-9
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4
First results of the double-blind randomized placebo-controlled multicenter clinical trial of DIM-based therapy designed as personalized approach to reverse prostatic intraepithelial neoplasia (PIN)
Autor: Igor Kuznetsov, Pavel Baranovskiy, Paltsev Mikhail A, Ekaterina Muyzhnek, Vadim Drukh, Evgeniya Andrianova, Vsevolod Kiselev
Publikováno v: The EPMA Journal
Targeted pharmacological correction is used extensively in medical practice today. 3,3'-Diindolylmethane (DIM) is known as a substance with various anticancer properties. An interim study of the efficacy of a new drug Infemin on the basis of diindoly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0c277a97f648ac14a647e75f12518a
https://doi.org/10.1186/s13167-016-0057-3
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5
Double-blind randomized placebo-controlled multicenter clinical trial (phase IIa) on diindolylmethane’s efficacy and safety in the treatment of CIN: implications for cervical cancer prevention
Autor: Igor Kuznetsov, Vsevolod Kiselev, Levon Ashrafian, I A Apolikhina, Vadim Drukh, Paltsev Mikhail A, Evgeniya Andrianova, Gennady T. Sukhikh, Ekaterina Muyzhnek
Publikováno v: The EPMA Journal
The article presents the results of a clinical trial on the efficacy and safety of a novel pharmaceutical composition in the form of vaginal suppositories containing diindolylmethane in the course of cervical intraepithelial neoplasia (CIN) I–II co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47dbf0ce6f643edb305df928bfadefb
https://doi.org/10.1186/s13167-015-0048-9
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6
Comparative preclinical pharmacokinetics study of 3,3′-diindolylmethane formulations: is personalized treatment and targeted chemoprevention in the horizon?
Autor: Ekaterina Muyzhnek, Vsevolod Kiselev, Vadim Drukh, Igor Kuznetsov, O. I. Pchelintseva, Paltsev Mikhail A
Publikováno v: The EPMA Journal
Background 3,3′-Diindolylmethane (DIM) is known as an agent of natural origin that provides protection against different cancers due to the broad spectrum of its biological activities in vivo. However, this substance has a very poor biodistribution
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c705eb19aa9f003ea6a85d7082fe87df
https://doi.org/10.1186/1878-5085-4-25
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7
Polymer Based Nano-Formulation of Diindolylmethane with High Oral Bioavailability
Autor: Eugenii Klinskiy, Alex, er Semov, Shengmin Lee, Vsevolod Kiselev, Ekaterina Muyzhnek, Valery Yu Alakhov
Publikováno v: Journal of Nanomedicine & Nanotechnology.
At the present, a high potential of 3,3’-diindolylmethane (DIM) as a new preventive and therapeutic agent in oncology is well established, due to its ability to target multiple components of cancer cell cycle regulation, survival and progression. H
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dcf3d0d95646d792925caf7bbda3eeab
https://doi.org/10.4172/2157-7439.1000162
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8
Block Copolymer Based Composition of Epigallocatechin-3-gallate with Improved Oral Bioavailability as a Way to Increase its Therapeutic Activity
Autor: Alex, Vsevolod Kiselev, Ekaterina Muyzhnek, re Semov, Evgueni Klinski, Valery Yu Alakhov, Xu Yan
Publikováno v: Journal of Nanomedicine & Biotherapeutic Discovery.
At the present, a high potential of epigallocatechin-3-gallate (EGCG) as a new preventive and therapeutic agent in oncology and several other indications is well established. EGCG exerts its antitumor activity through induction of cell cycle arrest a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d372dcc3038de27692d0287769c2043
https://doi.org/10.4172/2155-983x.1000117
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9
Safety and tolerability of DIM-based therapy designed as personalized approach to reverse prostatic intraepithelial neoplasia (PIN)
Autor: Vadim Drukh, Igor Kuznetsov, Paltsev Mikhail A, O. I. Pchelintseva, Ekaterina Muyzhnek, Vsevolod Kiselev
Publikováno v: The EPMA Journal
Background It has been shown previously that novel formulation of 3,3'-diindolylmethane (DIM) substance with high bioavailability (Infemin) inhibits tumor development due to the tumor growth rate reduction in the xenograft model of prostate cancer. P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c8349a37c4b2944cf97f5b1d5e56b7
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