Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Ekaterina L Grishchuk"'
Autor:
Anatoly V Zaytsev, Dario Segura-Peña, Maxim Godzi, Abram Calderon, Edward R Ballister, Rumen Stamatov, Alyssa M Mayo, Laura Peterson, Ben E Black, Fazly I Ataullakhanov, Michael A Lampson, Ekaterina L Grishchuk
Publikováno v:
eLife, Vol 5 (2016)
Aurora B kinase, a key regulator of cell division, localizes to specific cellular locations, but the regulatory mechanisms responsible for phosphorylation of substrates located remotely from kinase enrichment sites are unclear. Here, we provide evide
Externí odkaz:
https://doaj.org/article/39837891175341dba3219ee80954e578
Autor:
Ekaterina L Grishchuk
Publikováno v:
Molecular Systems Biology, Vol 5, Iss 1, Pp 1-2 (2009)
Externí odkaz:
https://doaj.org/article/9950d84a9c50468b8343305535c1f493
Autor:
Manas Chakraborty, Ekaterina V. Tarasovetc, Anatoly V. Zaytsev, Maxim Godzi, Ana C. Figueiredo, Fazly I. Ataullakhanov, Ekaterina L. Grishchuk
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
During cell division, it is currently unclear how kinetochores transit from lateral microtubule attachment to durable association to dynamic microtubule plus ends. Here, using in vitro reconstitution and computer modeling, the authors provide biophys
Externí odkaz:
https://doaj.org/article/ce917114ab1d4d2a9499e8a6eb19865d
Autor:
Prasad Trivedi, Anatoly V. Zaytsev, Maxim Godzi, Fazly I. Ataullakhanov, Ekaterina L. Grishchuk, P. Todd Stukenberg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
How the chromosome passenger complex (CPC) phosphorylates the kinetochores that can be a micron away to control mitotic events is unknown. Here the authors find that the CPC directly binds microtubules near inner centromeres, which controls its abili
Externí odkaz:
https://doaj.org/article/dc1b2464d5e3480a863990aff60e55d7
SummaryTo faithfully segregate chromosomes during vertebrate mitosis, kinetochore-microtubule interactions must be restricted to a single site on each chromosome. Prior work on pair-wise kinetochore protein interactions has been unable to identify th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad167228f3bf92792505991b6e046a36
https://doi.org/10.1101/2023.05.22.541649
https://doi.org/10.1101/2023.05.22.541649
Autor:
Wangxi Luo, Vladimir Demidov, Qi Shen, Hugo Girão, Manas Chakraborty, Aleksandr Maiorov, Fazly I. Ataullakhanov, Chenxiang Lin, Helder Maiato, Ekaterina L. Grishchuk
Publikováno v:
Science advances. 9(1)
CLASPs (cytoplasmic linker-associated proteins) are ubiquitous stabilizers of microtubule dynamics, but their molecular targets at the microtubule plus-end are not understood. Using DNA origami–based reconstructions, we show that clusters of human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5dc3c4f1188b0d3564398931223cb9
https://pubmed.ncbi.nlm.nih.gov/36598991
https://pubmed.ncbi.nlm.nih.gov/36598991
Autor:
Wangxi Luo, Vladimir Demidov, Qi Shen, Hugo Girão, Manas Chakraborty, Aleksandr Maiorov, Fazly I. Ataullakhanov, Chenxiang Lin, Helder Maiato, Ekaterina L. Grishchuk
CLASPs are ubiquitous stabilizers of microtubule dynamics but their molecular targets at the microtubule plus-end are not understood. Using DNA origami-based reconstructions we show that clusters of human CLASP2 form a load-bearing bond with terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb467daba42593722611282e10bc69d4
https://doi.org/10.1101/2022.04.25.489454
https://doi.org/10.1101/2022.04.25.489454
Autor:
Shaowen Wu, Ekaterina L. Grishchuk
Publikováno v:
Essays Biochem
In a dividing eukaryotic cell, proper chromosome segregation requires the dynamic yet persistent attachment of kinetochores to spindle microtubules. In the budding yeast Saccharomyces cerevisiae, this function is especially crucial because each kinet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ebcaf6a23cfa207b28419617c961ee
https://doi.org/10.1042/ebc20190079
https://doi.org/10.1042/ebc20190079
Autor:
Suvranta K. Tripathy, Vladimir M. Demidov, Ivan V. Gonchar, Shaowen Wu, Fazly I. Ataullakhanov, Ekaterina L. Grishchuk
Publikováno v:
Optical Tweezers ISBN: 9781071622285
Methods Mol Biol
Methods Mol Biol
Optical trapping has been instrumental for deciphering translocation mechanisms of the force-generating cytoskeletal proteins. However, studies of the dynamic interactions between microtubules (MTs) and MT-associated proteins (MAPs) with no motor act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187a9b2073ea091db068398f36017777
https://doi.org/10.1007/978-1-0716-2229-2_22
https://doi.org/10.1007/978-1-0716-2229-2_22
Autor:
Anatoly V. Zaytsev, P. Todd Stukenberg, Fazly I. Ataullakhanov, Maxim Godzi, Ekaterina L. Grishchuk, Prasad Trivedi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Nature Communications
Nature Communications
Proper chromosome segregation depends upon kinetochore phosphorylation by the Chromosome Passenger Complex (CPC). Current models suggest the activity of the CPC decreases in response to the inter-kinetochore stretch that accompanies the formation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff93ef7058a96e0cbf52972defe80b7
http://link.springer.com/article/10.1038/s41467-019-08418-4
http://link.springer.com/article/10.1038/s41467-019-08418-4