Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ekaterina Isaakova"'
Autor:
Daniel Solvie, Apoorva Baluapuri, Leonie Uhl, Daniel Fleischhauer, Theresa Endres, Dimitrios Papadopoulos, Amel Aziba, Abdallah Gaballa, Ivan Mikicic, Ekaterina Isaakova, Celeste Giansanti, Jennifer Jansen, Marvin Jungblut, Teresa Klein, Christina Schülein-Völk, Hans Maric, Sören Doose, Markus Sauer, Petra Beli, Andreas Rosenwald, Matthias Dobbelstein, Elmar Wolf, Martin Eilers
Publikováno v:
Nature. 612:148-155
Oncoproteins of the MYC family drive the development of numerous human tumours
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2602
The identification of modification sites for ubiquitin and ubiquitin-like modifiers is an essential step in the elucidation of controlled processes. The ubiquitin-like modifier NEDD8 is an important regulator of plethora of biological processes both
Autor:
Maria A. Lagarkova, Ekaterina A. Khomyakova, Iulia I. Pavlova, Vladimir B. Tsvetkov, Anna M. Varizhuk, Vassilii N. Lazarev, Ivan A. Lacis, Ekaterina Isaakova, Vyacheslav V. Severov, Galina E. Pozmogova
Publikováno v:
International Journal of Biological Macromolecules. 160:1144-1157
Affinity for G-quadruplex (G4) structures may be a common feature of transcription-facilitating histone chaperons (HCs). This assumption is based on previous unmatched studies of HCs FACT, nucleolin (NCL), BRD3, and ATRX. We verified this assumption
Autor:
Maria A. Lagarkova, Vjacheslav V. Severov, Galina E. Pozmogova, Timofei S. Zatsepin, Anton V. Turaev, Andrey V. Aralov, Ekaterina Isaakova, M. V. Sardushkin, Anna M. Varizhuk, A. N. Bogomazova
Publikováno v:
Biosensorsbioelectronics. 175
We report the design of robust sensors for measuring intracellular pH, based on the native DNA i-motifs (iMs) found in neurodegeneration- or carcinogenesis-related genes. Those iMs appear to be genomic regulatory elements and might modulate transcrip
Autor:
A.N. Bogomazova, Artem V. Luzhin, Galina E. Pozmogova, Maria A. Lagarkova, Omar L. Kantidze, Vjacheslav V. Severov, Anna Varizhuk, Tatjana Vedekhina, Polina Tikhonova, Ekaterina Isaakova, R. Sultanov, Ksenia Klimina, Vladimir B. Tsvetkov, Iulia I. Pavlova
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 7090, p 7090 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 7090, p 7090 (2021)
G-quadruplex (G4) sites in the human genome frequently colocalize with CCCTC-binding factor (CTCF)-bound sites in CpG islands (CGIs). We aimed to clarify the role of G4s in CTCF positioning. Molecular modeling data suggested direct interactions, so w
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 41(9)
Here, the emerging data on DNA G-quadruplexes (G4s) as epigenetic modulators are reviewed and integrated. This concept has appeared and evolved substantially in recent years. First, persistent G4s (e.g., those stabilized by exogenous ligands) were li