Progressive methylation of ageing histones by Dot1 functions as a timer

Autor: Gideon Oudgenoeg, Marit Terweij, A. F. Maarten Altelaar, Kitty F. Verzijlbergen, Dirk De Vos, Ekaterina Iachina, Albert J. R. Heck, Erik L. de Graaf, Fred van Leeuwen, Tibor van Welsem, Floor Frederiks, Jeroen Krijgsveld, Barbara M. Bakker

Publikováno v: de Vos, D L, Frederiks, F, Terweij, M, van Welsem, T, Verzijlbergen, K F, Iachina, E, de Graaf, E L, Altelaar, A F M, Oudgenoeg, G, Heck, A J R, Krijgsveld, J, Bakker, B M & van Leeuwen, F 2011, ' Progressive methylation of aging histones by Dot1 acts as a timer. ', EMBO Reports, vol. 12, pp. 956-962 . https://doi.org/10.1038/embor.2011.131
EMBO Reports, 12, 956-962. Nature Publishing Group
Embo Reports, 12(9), 956-962. Wiley

Post-translational modifications of histone proteins have a crucial role in regulating gene expression. If efficiently re-established after chromosome duplication, histone modifications could help propagate gene expression patterns in dividing cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb1d2c318e8fafb175ca4d49a63e6ca
https://pubmed.ncbi.nlm.nih.gov/21760613