The frequency of chromosomal aberrations in individuals chronically in contact with excess dosages of fluorides

Autor: Valentin P. Volobaev, Ekaterina E. Mikheeva, Ekaterina S. Lytkina, Alexey V. Larionov, Ekaterina A. Schetnikova, Elena B. Gurevich, Evgenia D. Vdovina, Elena P. Mishchenko

Publikováno v: Ecological genetics. 19:59-66

BACKGROUND: Chronic excess human exposure to fluorides is an underestimated problem. There is information that fluorides are capable of exerting a genotoxic effect in vitro and in vivo. The data obtained on human populations are limited and contradic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b51c87285bdc919ad0c5f17c28a44760
https://doi.org/10.17816/ecogen20645

Unraveling the Mechanisms of Sensitivity to Anti-FGF Therapies in Imatinib-Resistant Gastrointestinal Stromal Tumors (GIST) Lacking Secondary KIT Mutations.

Autor: Boichuk S; Department of Pathology, Kazan State Medical University, Kazan 420012, Russia.; Department of Radiotherapy and Radiology, Russian Medical Academy of Continuous Professional Education, Moscow 127051, Russia.; Central Research Laboratory, Kazan State Medical University, Kazan 420012, Russia.; Biomarker Research Laboratory, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia., Dunaev P; Department of Pathology, Kazan State Medical University, Kazan 420012, Russia., Skripova V; Biomarker Research Laboratory, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia., Galembikova A; Department of Pathology, Kazan State Medical University, Kazan 420012, Russia., Bikinieva F; Department of Pathology, Kazan State Medical University, Kazan 420012, Russia., Shagimardanova E; Regulatory Genomics Research Center, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia.; LIFT-Life Improvement by Future Technologies Institute, Moscow 121205, Russia.; Loginov Moscow Clinical Scientific Center, Moscow 111123, Russia., Gazizova G; Regulatory Genomics Research Center, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia., Deviatiiarov R; Regulatory Genomics Research Center, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia.; LIFT-Life Improvement by Future Technologies Institute, Moscow 121205, Russia., Valeeva E; Central Research Laboratory, Kazan State Medical University, Kazan 420012, Russia., Mikheeva E; Department of Pathology, Kazan State Medical University, Kazan 420012, Russia., Vasilyeva M; Cytogenetics Laboratory, Carcinogenesis Institute, N.N. Blokhin National Medical Research Center of Oncology, Moscow 115478, Russia., Kopnin P; Cytogenetics Laboratory, Carcinogenesis Institute, N.N. Blokhin National Medical Research Center of Oncology, Moscow 115478, Russia., Strelnikov V; Epigenetics Laboratory, Research Centre for Medical Genetics, Moscow 115522, Russia., Kiyamova R; Biomarker Research Laboratory, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia.

Publikováno v: Cancers [Cancers (Basel)] 2023 Nov 09; Vol. 15 (22). Date of Electronic Publication: 2023 Nov 09.

Inhibition of FGF2-Mediated Signaling in GIST-Promising Approach for Overcoming Resistance to Imatinib.

Autor: Boichuk S; Department of Pathology, Kazan State Medical University, 420012 Kazan, Russia.; Central Research Laboratory, Kazan State Medical University, 420012 Kazan, Russia., Galembikova A; Department of Pathology, Kazan State Medical University, 420012 Kazan, Russia., Mikheeva E; Department of Pathology, Kazan State Medical University, 420012 Kazan, Russia., Bikinieva F; Department of Pathology, Kazan State Medical University, 420012 Kazan, Russia., Aukhadieva A; Department of Pathology, Kazan State Medical University, 420012 Kazan, Russia., Dunaev P; Department of Pathology, Kazan State Medical University, 420012 Kazan, Russia., Khalikov D; Tatarstan Cancer Center, 420029 Kazan, Russia., Petrov S; Department of Pathology, Kazan State Medical University, 420012 Kazan, Russia.; Tatarstan Cancer Center, 420029 Kazan, Russia., Kurtasanov R; Tatarstan Cancer Center, 420029 Kazan, Russia., Valeeva E; Central Research Laboratory, Kazan State Medical University, 420012 Kazan, Russia., Kireev I; Department of Electron Microscopy, A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, 117997 Moscow, Russia., Dugina V; Department of Mathematical Methods in Biology, A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia., Lushnikova A; Oncogenomics Laboratory, Carcinogenesis Institute, N.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia., Novikova M; Cytogenetics Laboratory, Carcinogenesis Institute, N.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia., Kopnin P; Cytogenetics Laboratory, Carcinogenesis Institute, N.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.

Publikováno v: Cancers [Cancers (Basel)] 2020 Jun 24; Vol. 12 (6). Date of Electronic Publication: 2020 Jun 24.