Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ekaterina Bobrovnikova-Marjon"'
Autor:
M. Celeste Simon, Brian Keith, J. Alan Diehl, Ekaterina Bobrovnikova-Marjon, Alison Grazioli, Joshua D. Ochocki, Bo Li, Danielle J. Sanchez, Daniel Ackerman, Bo Qiu
Supplementary Figures S1 - S9: Supplementary Figure S1. Regulation of PLIN2 and other LD coat protein genes in ccRCC tissue. Supplementary Figure S2. PPARγ function is not required for PLIN2 expression in ccRCC. Supplementary Figure S3. HIF-2alpha d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850f4e8cf4e9ae476024ad56d66cdac2
https://doi.org/10.1158/2159-8290.22530018
https://doi.org/10.1158/2159-8290.22530018
Autor:
M. Celeste Simon, Brian Keith, J. Alan Diehl, Ekaterina Bobrovnikova-Marjon, Alison Grazioli, Joshua D. Ochocki, Bo Li, Danielle J. Sanchez, Daniel Ackerman, Bo Qiu
Supplementary Tables S1 - S3: Table S1. Expression of triglyceride synthesis genes in primary ccRCC (n=480) compared to normal kidney (n=69) samples. Table S2. Expression of cholesterol synthesis genes in primary ccRCC (n=480) compared to normal kidn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3958fed7a6e9c9fac001f0f60631bc7e
https://doi.org/10.1158/2159-8290.22530015.v1
https://doi.org/10.1158/2159-8290.22530015.v1
Autor:
M. Celeste Simon, Brian Keith, J. Alan Diehl, Ekaterina Bobrovnikova-Marjon, Alison Grazioli, Joshua D. Ochocki, Bo Li, Danielle J. Sanchez, Daniel Ackerman, Bo Qiu
Supplementary Figure Legends: Legends for all supplementary figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc2b4fdd325f5bea57289c080900dd1
https://doi.org/10.1158/2159-8290.22530021.v1
https://doi.org/10.1158/2159-8290.22530021.v1
Autor:
M. Celeste Simon, Brian Keith, J. Alan Diehl, Ekaterina Bobrovnikova-Marjon, Alison Grazioli, Joshua D. Ochocki, Bo Li, Danielle J. Sanchez, Daniel Ackerman, Bo Qiu
Supplemental Table Legends: Legends for all supplementary tables.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5da842bd0a24d2d6b6bbb257fdc56f
https://doi.org/10.1158/2159-8290.22530024
https://doi.org/10.1158/2159-8290.22530024
Autor:
Ekaterina Bobrovnikova-Marjon, Bo Li, J. Alan Diehl, Brian Keith, Bo Qiu, Alison Grazioli, Danielle J. Sanchez, Daniel Ackerman, Joshua D. Ochocki, M. Celeste Simon
Publikováno v:
Cancer Discovery. 5:652-667
Two hallmarks of clear-cell renal cell carcinoma (ccRCC) are constitutive hypoxia-inducible factor (HIF) signaling and abundant intracellular lipid droplets (LD). However, regulation of lipid storage and its role in ccRCC are incompletely understood.
Publikováno v:
Annual Review of Medicine. 65:157-170
Therapeutic strategies designed to target cancer metabolism are an area of intense research. Antimetabolites, first used to treat patients in the early twentieth century, served as an early proof of concept for such therapies. We highlight strategies
Autor:
Ekaterina Bobrovnikova-Marjon, Dariusz Pytel, Jake A. Kushner, Brian Frederick, Hui Zheng, Constantinos Koumenis, J. Alan Diehl, Nancy L. Maas, Nilesh Chitnis, Lewis A. Chodosh, Dhruv K. Pant, Serge Y. Fuchs
Publikováno v:
Molecular Cell. 48:353-364
MicroRNAs typically function at the level of posttranscriptional gene silencing within the cytoplasm; however, increasing evidence suggests that they may also function in nuclear, Argonaut-containing complexes, to directly repress target gene transcr
Autor:
Fangliang Zhang, Dariusz Pytel, Douglas R. Cavener, Jiangbin Ye, J A Diehl, Ekaterina Bobrovnikova-Marjon, Christina Grigoriadou, Constantinos Koumenis
Publikováno v:
Oncogene
To proliferate and expand in an environment with limited nutrients, cancer cells co-opt cellular regulatory pathways that facilitate adaptation and thereby maintain tumor growth and survival potential. The endoplasmic reticulum (ER) is uniquely posit
Autor:
Ekaterina Bobrovnikova-Marjon, Robert B. Hamanaka, Xinjun Ji, J A Diehl, Stephen A. Liebhaber
Publikováno v:
Oncogene
Exposure of cells to endoplasmic reticulum (ER) stress leads to activation of phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathway and transcriptional induction of the inhibitor of apoptosis family of proteins. One of the proximal effectors of
Autor:
Ekaterina Bobrovnikova-Marjon, J. Alan Diehl, M. Celeste Simon, Daniel Ackerman, Zachary L. Quinn, Anthony A. Mancuso, Dionysios N. Giannoukos, Liping Liu, Michaela Gruber, Brian Keith, Regina M. Young
Solid tumors exhibit heterogeneous microenvironments, often characterized by limiting concentrations of oxygen (O2), glucose, and other nutrients. How oncogenic mutations alter stress response pathways, metabolism, and cell survival in the face of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c91ee20ceb94e817bf06cf919e0a86
https://europepmc.org/articles/PMC3672646/
https://europepmc.org/articles/PMC3672646/