Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ekaterina B Likold"'
Autor:
Bella V. Biderman, Ekaterina B. Likold, Nataliya A. Severina, Tatiana N. Obukhova, Andrey B. Sudarikov
Publikováno v:
Genes
Volume 14
Issue 2
Pages: 532
Volume 14
Issue 2
Pages: 532
Chronic lymphocytic leukemia (CLL) is one of the most common B-cell malignancies in Western countries. IGHV mutational status is the most important prognostic factor for this disease. CLL is characterized by an extreme narrowing of the IGHV genes rep
Autor:
Eugene Nikitin, Darya A. Koroleva, E E Zvonkov, Ekaterina B Likold, B V Biderman, Al'-Radi Ls, Hunan Julhakyan, Andrey Sudarikov, Svetlana Smirnova
Publikováno v:
Clinical lymphoma, myelomaleukemia. 21(12)
Introduction Immunoglobulin heavy chain variable region (IGHV) repertoire narrowing could be an evidence for the involvement of a limited set of antigens in the development of lymphomas. For chronic lymphocytic leukemia (CLL) the existence of more th
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:S321
Background: Mutational status of the IGHV genes and B-cell receptor stereotype are the key prognostic factors for CLL. However, the routinely used Sanger sequencing technique may fail for cases with an expansion of more than one tumor B-cell clones,
Autor:
Ekaterina B Likold, Tatiana N. Obukhova, Andrey Sudarikov, V G Savchenko, Nataliya A. Severina, B V Biderman
Publikováno v:
Blood. 136:16-17
Background: The features of the IGHV gene repertoire in CLL have been widely discussed in the last 20 years. In approximately 30% of cases of CLL, highly homologous "stereotyped" antigen receptors (SARs) are expressed, representing quasi identical am
Autor:
Andrey Sudarikov, Natalya Severina, Hunan Julhakyan, Ekaterina B Likold, B V Biderman, T N Obukhova
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 20:S226
Background About 30% of cases of CLL express highly homologous “stereotype” antigenic receptors (SARs) which can be assigned to different subsets. Several SARs have already been identified as independent prognostic factors for CLL (CLL#1, CLL#2,