Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ekaterina A. Shaforostova"'
Autor:
Artem P. Gureev, Polina I. Babenkova, Veronika V. Nesterova, Arina D. Tsvetkova, Mariya V. Gryaznova, Ekaterina A. Shaforostova
Publikováno v:
Gastrointestinal Disorders, Vol 5, Iss 4, Pp 536-548 (2023)
L-carnitine plays a critical role in sperm functioning and maintaining male fertility. Mildronate is a widely used drug for treating cardiovascular diseases. Mildronate inhibits L-carnitine biosynthesis and transport into cells while increasing gluco
Externí odkaz:
https://doaj.org/article/3b27a338e0ac4f35815c7a4034454564
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Aging is a general degenerative process related to deterioration of cell functions in the entire organism. Mitochondria, which play a key role in energy homeostasis and metabolism of reactive oxygen species (ROS), require lifetime control and constan
Externí odkaz:
https://doaj.org/article/6d8d42148b7e4e3abab9e3536af71143
Publikováno v:
Metabolic Brain Disease. 37:2497-2510
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7120c1d0b030b721e17e52d1d6c053b1
https://doi.org/10.1007/s11011-022-01047-9
https://doi.org/10.1007/s11011-022-01047-9
Publikováno v:
Journal of Experimental Neuroscience, Vol 12 (2018)
β-guanidinopropionic acid (β-GPA) has been used as a nutritional supplement for increasing physical strength and endurance with positive and predictable results. In muscles, it works as a nonadaptive stimulator of mitochondria biogenesis; it also i
Externí odkaz:
https://doaj.org/article/7e39fa1a50d741f2b86613a8344b2f53
Autor:
Artem P. Gureev, Victoria G. Khorolskaya, Irina S. Sadovnikova, Ekaterina A. Shaforostova, Vadim R. Cherednichenko, Inna Y. Burakova, Egor Y. Plotnikov, Vasily N. Popov
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 15197
In this research, we compared the cognitive parameters of 2-, 7-, and 15-month-old mice, changes in mitochondrial DNA (mtDNA) integrity and expression of genes involved in the nuclear erythroid 2-related factor 2/antioxidant response element (Nrf2/AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b50a750c433d33bb539daacf4a1b80
https://pubmed.ncbi.nlm.nih.gov/36499517
https://pubmed.ncbi.nlm.nih.gov/36499517
Autor:
Daria E. Volodina, Artem P. Gureev, Ekaterina A. Shaforostova, Mariya V. Gryaznova, Daria A. Ignatyeva, Vasily N. Popov
Publikováno v:
Life sciences. 293
Ageing is the most significant risk factor for cardiovascular diseases. l-Carnitine has a potent cardioprotective effect and its synthesis decreases during ageing. At the same time, there are pharmaceuticals, such as mildronate which, on the contrary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627630f7aa19949370c53ba292258219
https://pubmed.ncbi.nlm.nih.gov/35051422
https://pubmed.ncbi.nlm.nih.gov/35051422
Autor:
Ekaterina A. Shaforostova, Denis A. Laver, Artem P. Gureev, Mikhail Y. Syromyatnikov, Vasily N. Popov, Victoria G. Khorolskaya
Publikováno v:
Journal of Applied Biomedicine. 17:107-114
Methylene blue (MB) is a promising compound with a broad range of neuroprotective activity. One of therapeutic effects is the activation of mitochondrial biogenesis via Nrf2/ARE signaling cascade. Probably, mild oxidative stress caused by MB-depended
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c12ce71a00cc65f322f86e29694f4b17
https://doi.org/10.32725/jab.2019.008
https://doi.org/10.32725/jab.2019.008
Publikováno v:
FEBS Letters. 593:499-503
Methylene blue (MB) is a promising prodrug to treat mitochondrial dysfunctions that is currently being used in clinical trials for Alzheimer’s disease. MB can penetrate the blood brain barrier, accumulating in brain mitochondria where it acts as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1eca8c66439453ea9e899e53cef33b
https://doi.org/10.1002/1873-3468.13332
https://doi.org/10.1002/1873-3468.13332
Publikováno v:
Biomeditsinskaia khimiia. 67(1)
Meldonium is a metabolic drug used for treatment of coronary heart disease. The effect of the drug lies in its ability to inhibit synthesis and transport of L-carnitine. At the same time, a long-term deficiency of L-carnitine can theoretically negati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde770b31427b8f0f76d55203d266ee9
https://pubmed.ncbi.nlm.nih.gov/33645524
https://pubmed.ncbi.nlm.nih.gov/33645524
Autor:
Artem P. Gureev, Vasily N. Popov, Ekaterina A. Shaforostova, Anatoly A. Starkov, Irina S. Sadovnikova
Publikováno v:
Archives of Biochemistry and Biophysics. 705:108892
Exhaustive physical exercises are potentially dangerous for human's physical health and may lead to chronic heart disease. Therefore, individuals involved in such activity require effective and safe cardioprotectors. The goal of this research was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b4796263a081fcd2b1631118cd6173
https://doi.org/10.1016/j.abb.2021.108892
https://doi.org/10.1016/j.abb.2021.108892