Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ekaterina A. Murashko"'
Autor:
Olga Chuprina, Nikolay Solovyev, V. N. Babakov, Andrey S. Radilov, Yaroslav A. Dubrovskii, Petr Bel'tyukov, Ekaterina A. Murashko
Publikováno v:
Talanta. 197:374-382
Organophosphates’ toxic effect causes covalent binding to serine-198 in the active site of human plasma butyrylcholinesterase (BChE) with loss of enzymatic function (covalent inhibition). Mass spectrometric detection of modified FGESAGAAS peptide a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1624e936ce18aa87fb2fc902637c34e1
https://doi.org/10.1016/j.talanta.2019.01.059
https://doi.org/10.1016/j.talanta.2019.01.059
Autor:
Ekaterina P. Podolskaya, Florian Nachon, John Mikler, Patrick Masson, Wei Jiang, Yaroslav A. Dubrovskii, Oksana Lockridge, Lawrence M. Schopfer, V. N. Babakov, Ekaterina A. Murashko
Publikováno v:
Analytical Biochemistry. 439:132-141
Exposure to nerve agents or organophosphorus (OP) pesticides can have life-threatening effects. Human plasma butyrylcholinesterase (BChE) inactivates these poisons by binding them to Ser198. After hours or days, these OP adducts acquire a negative ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f41336cbe4dfc3af166031055a76b4
https://doi.org/10.1016/j.ab.2013.04.018
https://doi.org/10.1016/j.ab.2013.04.018
PHOS-Select Iron Affinity beads enrich peptides for detection of organophosphorus adducts on albumin
Autor:
Ekaterina A. Murashko, Patrick Masson, Florian Nachon, Ekaterina P. Podolskaya, Lawrence M. Schopfer, V. N. Babakov, Oksana Lockridge, Yaroslav A. Dubrovskii, Wei Jiang
Albumin is covalently modified by organophosphorus toxicants (OP) on tyrosine 411, but less than 1% of albumin is modified in humans by lethal OP doses that inhibit 95% of plasma butyrylcholinesterase. A method that enriches OP-modified albumin pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8475f15c72018044b8369bbb591ec0e2
https://europepmc.org/articles/PMC3886839/
https://europepmc.org/articles/PMC3886839/
