Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ekaterina A. Glubokova"'
Autor:
Irina A. Leneva, Daria I. Smirnova, Nadezhda P. Kartashova, Anastasiia V. Gracheva, Anna V. Ivanina, Ekaterina A. Glubokova, Ekaterina R. Korchevaya, Andrey A. Pancratov, Galina V. Trunova, Varvara A. Khokhlova, Oksana A. Svitich, Vitaly V. Zverev, Evgeny B. Faizuloev
Publikováno v:
Вопросы вирусологии, Vol 67, Iss 5, Pp 439-449 (2022)
Introduction. The variability of SARS-CoV-2 appeared to be higher than expected, the emergence of new variants raises concerns. The aim of the work was to compare the pathogenicity of the Wuhan and BA.1.1/Omicron variants in BALB/c mice and Syrian
Externí odkaz:
https://doaj.org/article/a4755c02985b4bf8808db15e4200e28d
Autor:
Irina A. Leneva, Irina N. Falynskova, Nailya R. Makhmudova, Ekaterina A. Glubokova, Nadezhda P. Kartashova, Eugenia I. Leonova, Natalya A. Mikhailova, Irina V. Shestakova
Publikováno v:
Microbiology Independent Research Journal, Vol 4, Iss 1, Pp 52-57 (2018)
Pneumonia often occurs as secondary infection post influenza disease and accounts for a large proportion of the morbidity and mortality associated with seasonal and pandemic influenza outbreaks. The antiviral drug triazavirine is licensed in Russia f
Externí odkaz:
https://doaj.org/article/bd110ac480934d418afc15cdc34761ae
Autor:
Ekaterina A Glubokova, Irina A. Leneva, Nikolai Yu. Kuznetsov, Rabdan M. Tikhov, Nadezda P. Kartashova, Irina N. Falynskova
Publikováno v:
Acta Naturae
The World Health Organization (WHO) recommends antivirals as an additional line of defense against influenza. One of such drugs is rimantadine. However, most of the circulating strains of influenza A viruses are resistant to this drug. Thus, a search
Autor:
Svetlana I Iarovenko, Karlsen Aa, Irina A. Leneva, Alexey A Ryakhovskiy, I A Potemkin, K. K. Kyuregyan, M. I. Mikhailov, Nadezhda P. Kartashova, Ekaterina A Glubokova
Publikováno v:
Acta virologica. 65:82-88
Hepatitis B virus (HBV) is a partially double-stranded DNA virus that specifically targets hepatocytes. It is considered a major health issue due to its high prevalence and the life-threatening consequences of chronic infection, including liver cirrh
Autor:
Andrei A Ivashchenko, Ekaterina A Glubokova, Vladimir A. Aladinskiy, Dmitry V. Kravchenko, Oleg D. Mitkin, Alexander V Nikitin, Irina N. Falynskova, Ruben N. Karapetian, Jeremy C. Jones, Irina A. Leneva, Elena A. Govorkova, Alexey A Ryakhovskiy, Alexandre V. Ivachtchenko, Stephan V Mochalov, Angela G. Koryakova
Publikováno v:
J Antimicrob Chemother
Background The development and clinical implementation of the cap-dependent endonuclease (CEN) inhibitor baloxavir marboxil was a breakthrough in influenza therapy, but it was associated with the emergence of drug-resistant variants. Objectives To de
Autor:
Ruben N. Karapetian, Alexey A Ryakhovskiy, Alexander V Nikitin, Oleg D. Mitkin, Elena A. Govorkova, Angela G. Koryakova, Jeremy C. Jones, Irina A. Leneva, Ekaterina A Glubokova, Alexandre V. Ivachtchenko, Andrei A Ivashchenko, Dmitry V. Kravchenko, Vladimir A. Aladinskiy, Irina N. Falynskova
Publikováno v:
Journal of medicinal chemistry. 63(17)
4-Substituted 2,4-dioxobutanoic acids inhibit influenza virus cap-dependent endonuclease (CEN) activity. Baloxavir marboxil, 4, is approved for treating influenza virus infections. We describe here the synthesis and biological evaluation of active co
Autor:
Nadezhda P. Kartashova, Irina A. Leneva, Anastasiia Gracheva, Ravil Khamitov, E. B. Faizuloev, V. N. Shchukina, Svetlana Loginova, Artem Poromov, Ekaterina A Glubokova, Olga V. Borisova, Ekaterina Korchevaya, Anna Shtro
Publikováno v:
Viruses
Volume 13
Issue 8
Viruses, Vol 13, Iss 1665, p 1665 (2021)
Volume 13
Issue 8
Viruses, Vol 13, Iss 1665, p 1665 (2021)
An escalating pandemic of the novel SARS-CoV-2 virus is impacting global health, and effective antivirals are needed. Umifenovir (Arbidol) is an indole-derivative molecule, licensed in Russia and China for prophylaxis and treatment of influenza and o
Autor:
Eugenia I. Leonova, Nailya R. Makhmudova, Irina A. Leneva, Irina V. Shestakova, Natalya A. Mikhailova, Nadezhda P. Kartashova, Ekaterina A Glubokova, Irina N. Falynskova
Publikováno v:
Microbiology Independent Research Journal, Vol 4, Iss 1, Pp 52-57 (2017)
Pneumonia often occurs as secondary infection post influenza disease and accounts for a large proportion of the morbidity and mortality associated with seasonal and pandemic influenza outbreaks. The antiviral drug triazavirine is licensed in Russia f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec40e585c7e8d73ffd5d4657bba03d2
https://zenodo.org/record/3840522
https://zenodo.org/record/3840522