Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ekaterina A Maltseva"'
Autor:
Maria V. Sukhanova, Rashid O. Anarbaev, Ekaterina A. Maltseva, Mikhail M. Kutuzov, Olga I. Lavrik
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract The formation of nuclear biomolecular condensates is often associated with local accumulation of proteins at a site of DNA damage. The key role in the formation of DNA repair foci belongs to PARP1, which is a sensor of DNA damage and catalyz
Externí odkaz:
https://doaj.org/article/4345651c06e44d94a1015d06dede364d
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190782 (2018)
Replication protein A (RPA) and the xeroderma pigmentosum group A (XPA) protein are indispensable for both pathways of nucleotide excision repair (NER). Here we analyze the interaction of RPA and XPA with DNA containing a flap and different size gaps
Externí odkaz:
https://doaj.org/article/6dcf5505b6414436929e59d5f3fe70f0
Autor:
Yuliya S. Krasikova, Ekaterina A. Maltseva, Svetlana N. Khodyreva, Alexey N. Evdokimov, Nadejda I. Rechkunova, Olga I. Lavrik
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 814 (2024)
Nucleotide excision repair (NER) is the most universal repair pathway, which removes a wide range of DNA helix-distorting lesions caused by chemical or physical agents. The final steps of this repair process are gap-filling repair synthesis and subse
Externí odkaz:
https://doaj.org/article/173960b440204f52bfbfc23513e3f93f
Autor:
Natalia A. Lebedeva, Rashid O. Anarbaev, Ekaterina A. Maltseva, Maria V. Sukhanova, Nadejda I. Rechkunova, Olga I. Lavrik
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6927 (2024)
Non-membrane compartments or biomolecular condensates play an important role in the regulation of cellular processes including DNA repair. Here, an ability of XRCC1, a scaffold protein involved in DNA base excision repair (BER) and single-strand brea
Externí odkaz:
https://doaj.org/article/b367756275d94f7d868901c96183ce06
Autor:
Svetlana N. Khodyreva, Ekaterina S. Ilina, Nadezhda S. Dyrkheeva, Alina S. Kochetkova, Alexandra A. Yamskikh, Ekaterina A. Maltseva, Anastasia A. Malakhova, Sergey P. Medvedev, Suren M. Zakian, Olga I. Lavrik
Publikováno v:
Cells, Vol 13, Iss 4, p 302 (2024)
Base excision repair (BER) is the predominant pathway for the removal of most forms of hydrolytic, oxidative, and alkylative DNA lesions. The precise functioning of BER is achieved via the regulation of each step by regulatory/accessory proteins, wit
Externí odkaz:
https://doaj.org/article/0983d4f52fdc49359c9bed4462992ed4
Autor:
Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/551c09fde19346b8adeeea88bf4b74d2
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13200 (2022)
Fused in sarcoma (FUS) is involved in the regulation of RNA and DNA metabolism. FUS participates in the formation of biomolecular condensates driven by phase transition. FUS is prone to self-aggregation and tends to undergo phase transition both with
Externí odkaz:
https://doaj.org/article/4c6544d5e49e41bd8c00b74951229935
Autor:
Elizaveta O. Boldinova, Ekaterina A. Belousova, Diana I. Gagarinskaya, Ekaterina A. Maltseva, Svetlana N. Khodyreva, Olga I. Lavrik, Alena V. Makarova
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 23, p 9027 (2020)
Human PrimPol is a unique enzyme possessing DNA/RNA primase and DNA polymerase activities. In this work, we demonstrated that PrimPol efficiently fills a 5-nt gap and possesses the conditional strand displacement activity stimulated by Mn2+ ions and
Externí odkaz:
https://doaj.org/article/899d4a6ed2f04a23b702553083f99fd4
Autor:
Tatyana A. Kurgina, Stanislav I. Shram, Mikhail M. Kutuzov, Tatyana V. Abramova, Tatyana A. Shcherbakova, Ekaterina A. Maltseva, Vladimir V. Poroikov, Olga I. Lavrik, Vytas K. Švedas, Dmitry K. Nilov
Publikováno v:
Biochemistry. Biokhimiia. 87(8)
Previously, we have found that a nucleic acid metabolite, 7-methylguanine (7mGua), produced in the body can have an inhibitory effect on the poly(ADP-ribose) polymerase 1 (PARP1) enzyme, an important pharmacological target in anticancer therapy. In t
Autor:
Ekaterina Yuryevna Maltseva
Publikováno v:
Samara Journal of Science. 10:277-280
The aim of the research is to define the structure of the teachers readiness for creating and implementing inclusive technologies into the educational process. This problem is relevant nowadays due to the requirements for teachers functions that are