Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ekaterina, Proshkina"'
Autor:
Alexey Moskalev, Zulfiya Guvatova, Mikhail Shaposhnikov, Ekaterina Lashmanova, Ekaterina Proshkina, Liubov Koval, Alex Zhavoronkov, George Krasnov, Anna Kudryavtseva
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Some effects of aging in animals are tissue-specific. In D. melanogaster neuronal overexpression of Gclc increases lifespan and improves certain physiological parameters associated with health benefits such as locomotor activity, circadian rhythmicit
Externí odkaz:
https://doaj.org/article/7081e271ec70420584460ffccefbd56d
Autor:
Ekaterina Proshkina, Elena Yushkova, Liubov Koval, Nadezhda Zemskaya, Evgeniya Shchegoleva, Ilya Solovev, Daria Yakovleva, Natalya Pakshina, Natalia Ulyasheva, Mikhail Shaposhnikov, Alexey Moskalev
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2396 (2021)
Small RNAs are essential to coordinate many cellular processes, including the regulation of gene expression patterns, the prevention of genomic instability, and the suppression of the mutagenic transposon activity. These processes determine the aging
Externí odkaz:
https://doaj.org/article/f902d9ebd5c6498789894393efbef7af
Autor:
Ekaterina Proshkina, Sergey Plyusnin, Tatyana Babak, Ekaterina Lashmanova, Faniya Maganova, Liubov Koval, Elena Platonova, Mikhail Shaposhnikov, Alexey Moskalev
Publikováno v:
Antioxidants, Vol 9, Iss 6, p 529 (2020)
Terpenes and terpenoids are the largest groups of plant secondary metabolites. However, unlike polyphenols, they are rarely associated with geroprotective properties. Here we evaluated the conformity of the biological effects of terpenoids with the c
Externí odkaz:
https://doaj.org/article/68c4fb03058c4336a54848d572338a59
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4484 (2020)
Throughout life, organisms are exposed to various exogenous and endogenous factors that cause DNA damages and somatic mutations provoking genomic instability. At a young age, compensatory mechanisms of genome protection are activated to prevent pheno
Externí odkaz:
https://doaj.org/article/167593257a2747269b8941e693a1e88d
Autor:
Ekaterina Lashmanova, Nadezhda Zemskaya, Ekaterina Proshkina, Anna Kudryavtseva, Marina Volosnikova, Elena Marusich, Sergey Leonov, Alex Zhavoronkov, Alexey Moskalev
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Flavonoids is an intensively studied group of natural compounds with antioxidant, antineoplastic, antihyperglycemic, cardioprotective, and neuroprotective properties. The present study intends to investigate the geroprotective action of three selecte
Externí odkaz:
https://doaj.org/article/a74444cb8f3e40b38f0f30dc6ed079f5
Publikováno v:
Молекулярная биология. 54:883-921
The mechanisms of aging are described at the molecular, cell, tissue, and systemic levels. Primary age-dependent molecular lesions activate the cell stress response to compensate for the resulting defects, but the mechanisms that recover and maintain
Autor:
Ilya Solovev, Elena Yushkova, Daria Yakovleva, Alexey Moskalev, Evgeniya Shchegoleva, Nadezhda Zemskaya, Ekaterina Proshkina, Natalya R. Pakshina, Natalia S. Ulyasheva, Liubov Koval, Mikhail Shaposhnikov
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2396, p 2396 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 5
International Journal of Molecular Sciences
Volume 22
Issue 5
Small RNAs are essential for the coordination of many cellular processes, including the regulation of gene expression patterns, the prevention of genomic instability, and the suppression of mutagenic transposon activity. These processes determine agi
Autor:
Alexander Fedintsev, Alexey A Alekseev, Ekaterina Proshkina, Alexey Moskalev, Mikhail V. Shaposhnikov, S.N. Balybin, Alexei A Belyi
Publikováno v:
Antioxidants, Vol 9, Iss 1239, p 1239 (2020)
Antioxidants
Volume 9
Issue 12
Antioxidants
Volume 9
Issue 12
We studied how aging affects the ability of Drosophila melanogaster to tolerate various types of stress factors. Data were obtained on the resistance of D. melanogaster to oxidative and genotoxic (separately paraquat, Fe3+, Cu2+, and Zn2+ ions), prot
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4484, p 4484 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Throughout life, organisms are exposed to various exogenous and endogenous factors that cause DNA damages and somatic mutations provoking genomic instability. At a young age, compensatory mechanisms of genome protection are activated to prevent pheno
Autor:
M. Shaposhnikov, Lyubov А. Koval, Alex Zhavoronkov, Ekaterina Proshkina, Alexey Moskalev, Nadezhda Zemskaya
Publikováno v:
Aging (Albany NY)
Recent experimental studies highlighted the role of hydrogen sulfide (H2S) in aging and longevity. The cystathionine s-synthase (CBS) and cystathionine γ-lyase (CSE) are the key enzymes responsible for H2S production. Here we investigated the geropr