Výsledky vyhledávání - "Ekaterina, Belova"

Akademický článek

Evidence blocks for effective presentation of genomic findings at molecular tumor boards: Single institution experience

Autor: Alexandra Lebedeva, Olesya Kuznetsova, Maxim Ivanov, Alexandra Kavun, Egor Veselovsky, Ekaterina Belova, Vladislav Mileyko, Valentina Yakushina, Polina Shilo, Alexey Tryakin, Alexey Rumyantsev, Fedor Moiseenko, Mikhail Fedyanin, Dmitry Nosov

Publikováno v: Heliyon, Vol 10, Iss 9, Pp e30303- (2024)

Genomic profiling, or molecular profiling of the tumor, is becoming a key component of therapeutic decision making in clinical oncology, and is typically carried out via next generation sequencing. However, the interpretation of the results and evalu

Externí odkaz: https://doaj.org/article/7718f5a3b252465981cb2c0b26fb09e4

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Akademický článek

Case Report: Progressive disease of BRCA2-mutant colon adenocarcinoma following talazoparib therapy

Autor: Elizaveta Polyanskaya, Alexandra Lebedeva, Olesya Kuznetsova, Ekaterina Belova, Alexandra Kavun, Maxim Ivanov, Mikhail Fedyanin, Alexey Tryakin, Vladislav Mileyko, Dmitry Nosov

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

Colorectal cancer (CRC) is currently one of the most common tumor types diagnosed worldwide. In the early stages, the disease responds well to surgical and chemotherapeutic treatment, but in the later stages when therapeutic options are exhausted, co

Externí odkaz: https://doaj.org/article/1d2c8448ae5e4200969af1ec70e054f3

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Akademický článek

A Method for Calculating the Sign and Degree of Chirality of Supercoiled Protein Structures

Autor: Aleksey Lutsenko, Alla Sidorova, Denis Shpigun, Ekaterina Belova, Vsevolod Tverdislov

Publikováno v: Symmetry, Vol 15, Iss 11, p 2051 (2023)

Chirality plays an important role in studies of natural protein structures. Therefore, much attention is paid to solving the problems associated with the development of criteria and methods for assessing the chirality of biomolecules. In this paper,

Externí odkaz: https://doaj.org/article/0145db0485cc448a8fe65b53fe7f9452

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Akademický článek

CeO2-Azacrown Conjugate as a Nanoplatform for Combined Radiopharmaceuticals

Autor: Sofia Khabirova, Gleb Aleshin, Tatiana Plakhova, Anastasia Zubenko, Anna Shchukina, Olga Fedorova, Aleksey Averin, Ekaterina Belova, Elena Bazarkina, Kristina Kvashnina, Stepan Kalmykov

Publikováno v: Nanomaterials, Vol 12, Iss 24, p 4484 (2022)

This study is one of the first attempts to assess CeO2 nanoparticles as a nanoplatform for radiopharmaceuticals with radionuclides. The process of functionalization using a bifunctional azacrown ligand is described, and the resulting conjugates are c

Externí odkaz: https://doaj.org/article/bc9c255643ca4df3a7d7892cfb5ac8c0

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Akademický článek

Molecular Dynamics Simulation Study of the Self-Assembly of Phenylalanine Peptide Nanotubes

Autor: Vladimir Bystrov, Ilya Likhachev, Alla Sidorova, Sergey Filippov, Aleksey Lutsenko, Denis Shpigun, Ekaterina Belova

Publikováno v: Nanomaterials, Vol 12, Iss 5, p 861 (2022)

In this paper, we propose and use a new approach for a relatively simple technique for conducting MD simulation (MDS) of various molecular nanostructures, determining the trajectory of the MD run and forming the final structure using external force a

Externí odkaz: https://doaj.org/article/9e80c974fa80439f84cbc2f722a43cff

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Akademický článek

Quantitative Assessment of Chirality of Protein Secondary Structures and Phenylalanine Peptide Nanotubes

Autor: Alla Sidorova, Vladimir Bystrov, Aleksey Lutsenko, Denis Shpigun, Ekaterina Belova, Ilya Likhachev

Publikováno v: Nanomaterials, Vol 11, Iss 12, p 3299 (2021)

In this study we consider the features of spatial-structure formation in proteins and their application in bioengineering. Methods for the quantitative assessment of the chirality of regular helical and irregular structures of proteins are presented.

Externí odkaz: https://doaj.org/article/a0ba31a0363e402ba19f31f293cf3476

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