Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ekansh Mittal"'
Autor:
Steven J. Grigsby, G.V.R. Krishna Prasad, Joshua B. Wallach, Ekansh Mittal, Fong-Fu Hsu, Dirk Schnappinger, Jennifer A. Philips
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114201- (2024)
Externí odkaz:
https://doaj.org/article/a32504df14934b809f3f49f6039f5fbf
Autor:
Suhas Bobba, Kuldeep S Chauhan, Sadia Akter, Shibali Das, Ekansh Mittal, Barun Mathema, Jennifer A Philips, Shabaana A Khader
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012137 (2024)
Interleukin-1 (IL-1) signaling is essential for controlling virulent Mycobacterium tuberculosis (Mtb) infection since antagonism of this pathway leads to exacerbated pathology and increased susceptibility. In contrast, the triggering of type I interf
Externí odkaz:
https://doaj.org/article/3a448097dc6140aeb41f6248c637dd4e
Autor:
Ekansh Mittal, Andrew T Roth, Anushree Seth, Srikanth Singamaneni, Wandy Beatty, Jennifer A Philips
Publikováno v:
eLife, Vol 12 (2023)
For decades, investigators have studied the interaction of Mycobacterium tuberculosis (Mtb) with macrophages, which serve as a major cellular niche for the bacilli. Because Mtb are prone to aggregation, investigators rely on varied methods to disaggr
Externí odkaz:
https://doaj.org/article/ad577b3d929f4fe09cba9e84904cec0c
Publikováno v:
Sensors, Vol 23, Iss 3, p 1265 (2023)
The imbalance in the gut microbiome plays a vital role in the progression of many diseases, including cancer, due to increased inflammation in the body. Since gut microbiome-induced inflammation can serve as a novel therapeutic strategy, there is an
Externí odkaz:
https://doaj.org/article/d20e63d02f2d49d4aa22208f2bb50b80
Autor:
Ekansh Mittal, Michael L. Skowyra, Grace Uwase, Emir Tinaztepe, Alka Mehra, Stefan Köster, Phyllis I. Hanson, Jennifer A. Philips
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
ABSTRACT Intracellular pathogens have varied strategies to breach the endolysosomal barrier so that they can deliver effectors to the host cytosol, access nutrients, replicate in the cytoplasm, and avoid degradation in the lysosome. In the case of My
Externí odkaz:
https://doaj.org/article/c4bdf88233dc4f09936ec76bdaa9891d
Autor:
Ekansh Mittal, David Qian
Breast cancer is the most frequently diagnosed cancer and the second largest cause of cancer deaths in women. However, drug resistance and poor response to treatments are common. Thus, there is an unmet need to identify new treatments and effective l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3560c1545565095bc5fbaf9114b47519
https://doi.org/10.1101/2023.05.14.540701
https://doi.org/10.1101/2023.05.14.540701
Autor:
Andrew T Roth, Ekansh Mittal, Anushree Seth, Srikanth Singamaneni, Wandy Beatty, Jennifer A Philips
Publikováno v:
eLife. 12
For decades, investigators have studied the interaction of Mycobacterium tuberculosis (Mtb) with macrophages, which serve as a major cellular niche for the bacilli. Because Mtb are prone to aggregation, investigators rely on varied methods to disaggr
Various studies have identified that natural herbs can be repurposed to treat infectious and bacterial diseases. The purpose of this study is first to test the medicinal value of five herbs including asafoetida, cumin, fenugreek, neem, and turmeric a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf55df55a2e614e84b787985906dee51
https://doi.org/10.1101/2022.11.29.518436
https://doi.org/10.1101/2022.11.29.518436
MotivationThe heterogeneous nature of cancers with multiple subtypes makes them challenging to treat. However, multi-omics data can be used to identify new therapeutic targets and we established a computational strategy to improve data mining.Results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f286971d9e741d8b3517478673395af
https://doi.org/10.1101/2022.11.20.517258
https://doi.org/10.1101/2022.11.20.517258