Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ekaitz Errasti- Murugarren"'
Autor:
Meritxell Espino Guarch, Mariona Font-Llitjós, Silvia Murillo-Cuesta, Ekaitz Errasti- Murugarren, Adelaida M Celaya, Giorgia Girotto, Dragana Vuckovic, Massimo Mezzavilla, Clara Vilches, Susanna Bodoy, Ignasi Sahún, Laura González, Esther Prat, Antonio Zorzano, Mara Dierssen, Isabel Varela-Nieto, Paolo Gasparini, Manuel Palacín, Virginia Nunes
Publikováno v:
eLife, Vol 7 (2018)
Age-related hearing loss (ARHL) is the most common sensory deficit in the elderly. The disease has a multifactorial etiology with both environmental and genetic factors involved being largely unknown. SLC7A8/SLC3A2 heterodimer is a neutral amino acid
Externí odkaz:
https://doaj.org/article/503c7861f97c46ce95ce9813d6079273
Autor:
Josep Rullo-Tubau, Maria Martinez-Molledo, Paola Bartoccioni, Ignasi Puch-Giner, Ángela Arias, Suwipa Saen-Oon, Camille Stephan-Otto Attolini, Rafael Artuch, Lucía Díaz, Víctor Guallar, Ekaitz Errasti-Murugarren, Manuel Palacín, Oscar Llorca
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Recent cryoEM studies elucidated details of the structural basis for the substrate selectivity and translocation of heteromeric amino acid transporters. However, Asc1/CD98hc is the only neutral heteromeric amino acid transporter that can fun
Externí odkaz:
https://doaj.org/article/303465180c3d4a2ba1178ad277af7a3c
Autor:
Clara Mayayo-Vallverdú, Esther Prat, Marta Vecino-Pérez, Laura González, Silvia Gràcia-Garcia, Luz San Miguel, Noelia Lopera, Angela Arias, Rafael Artuch, Miguel López de Heredia, Carlos Torrecilla, Ferran Rousaud-Barón, Oriol Angerri, Ekaitz Errasti-Murugarren, Virginia Nunes
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17140 (2023)
More than 20 years have passed since the identification of SLC3A1 and SLC7A9 as causative genes for cystinuria. However, cystinuria patients exhibit significant variability in the age of lithiasis onset, recurrence, and response to treatment, suggest
Externí odkaz:
https://doaj.org/article/b47f336ca4484d1d9c4d9ed53154c5bd
Autor:
Ekaitz Errasti-Murugarren, Joana Fort, Paola Bartoccioni, Lucía Díaz, Els Pardon, Xavier Carpena, Meritxell Espino-Guarch, Antonio Zorzano, Christine Ziegler, Jan Steyaert, Juan Fernández-Recio, Ignacio Fita, Manuel Palacín
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
L-Amino acid Transporters (LATs) are asymmetric amino acid exchangers. Here the authors determine the crystal structure of a prokaryotic LAT, the alanine-serine-cysteine exchanger (BasC) and identify key residues for asymmetric substrate interaction
Externí odkaz:
https://doaj.org/article/02f00387781745f491d1d369e1db2215
Autor:
Adrià Pla-Casillanis, Laura Ferigle, Marta Alonso-Gardón, Efren Xicoy-Espaulella, Ekaitz Errasti-Murugarren, Daniela Marazziti, Raúl Estévez
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5528 (2022)
Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare type of vacuolating leukodystrophy (white matter disorder), which is mainly caused by defects in MLC1 or glial cell adhesion molecule (GlialCAM) proteins. In addition, autoant
Externí odkaz:
https://doaj.org/article/cadd853908884078b4073fa294b2bf22
Publikováno v:
Membranes, Vol 11, Iss 8, p 602 (2021)
The mammalian SLC7 family comprises the L-amino acid transporters (LATs) and the cationic amino acid transporters (CATs). The relevance of these transporters is highlighted by their involvement in several human pathologies, including inherited rare d
Externí odkaz:
https://doaj.org/article/34510d7bda9e4441916038411570b465
Autor:
Emilia Boiadjieva Knöpfel, Clara Vilches, Simone M. R. Camargo, Ekaitz Errasti-Murugarren, Andrina Stäubli, Clara Mayayo, Francis L. Munier, Nataliya Miroshnikova, Nadège Poncet, Alexandra Junza, Shomi S. Bhattacharya, Esther Prat, Vanita Berry, Wolfgang Berger, Elise Heon, Anthony T. Moore, Óscar Yanes, Virginia Nunes, Manuel Palacín, Francois Verrey, Barbara Kloeckener-Gruissem
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Cataract, the loss of ocular lens transparency, accounts for ∼50% of worldwide blindness and has been associated with water and solute transport dysfunction across lens cellular barriers. We show that neutral amino acid antiporter LAT2 (Slc7a8) and
Externí odkaz:
https://doaj.org/article/0d94c545a0ee46fbbf4929482b25efc7
Publikováno v:
Membranes, Vol 11, Iss 2, p 155 (2021)
Accounting for nearly two-thirds of known druggable targets, membrane proteins are highly relevant for cell physiology and pharmacology. In this regard, the structural determination of pharmacologically relevant targets would facilitate the intellige
Externí odkaz:
https://doaj.org/article/d8c666bce04e41a5aa79026fc094732e
Autor:
Paola Bartoccioni, Manuel Palacín, Pablo Ballester, Andres Felipe Sierra, Luis Martínez-Crespo, Jia Liang Sun-Wang, Gemma Aragay, Ekaitz Errasti-Murugarren
Publikováno v:
Chem. 6:3054-3070
Summary The transport of anions and cations through liposomal membranes facilitated by synthetic carriers has been widely described. In contrast, analogous studies describing the facilitated transport of amino acids (aa) are scarce. We describe the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0718263c5d76dc2119d72994017175
https://doi.org/10.1016/j.chempr.2020.08.018
https://doi.org/10.1016/j.chempr.2020.08.018
Autor:
Adria? Pla-Casillanis 1, Laura Ferigle 1, Marta Alonso-Gardo?n 1, Efren Xicoy-Espaulella 1, Ekaitz Errasti-Murugarren 2, 3, Daniela Marazziti 4, Rau?l Este?vez 1
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
International journal of molecular sciences
23 (2022): 5528–5540. doi:10.3390/ijms23105528
info:cnr-pdr/source/autori:Adria? Pla-Casillanis 1,+, Laura Ferigle 1,+, Marta Alonso-Gardo?n 1, Efren Xicoy-Espaulella 1, Ekaitz Errasti-Murugarren 2,3, Daniela Marazziti 4 and Rau?l Este?vez 1,3,*/titolo:GPR37 receptors and Megalencephalic Leukoencephalopathy with subcortical Cysts/doi:10.3390%2Fijms23105528/rivista:International journal of molecular sciences (Print)/anno:2022/pagina_da:5528/pagina_a:5540/intervallo_pagine:5528–5540/volume:23
Universidad de Barcelona
International journal of molecular sciences
23 (2022): 5528–5540. doi:10.3390/ijms23105528
info:cnr-pdr/source/autori:Adria? Pla-Casillanis 1,+, Laura Ferigle 1,+, Marta Alonso-Gardo?n 1, Efren Xicoy-Espaulella 1, Ekaitz Errasti-Murugarren 2,3, Daniela Marazziti 4 and Rau?l Este?vez 1,3,*/titolo:GPR37 receptors and Megalencephalic Leukoencephalopathy with subcortical Cysts/doi:10.3390%2Fijms23105528/rivista:International journal of molecular sciences (Print)/anno:2022/pagina_da:5528/pagina_a:5540/intervallo_pagine:5528–5540/volume:23
Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare type of vacuolating leukodystrophy (white matter disorder), which is mainly caused by defects in MLC1 or glial cell adhesion molecule (GlialCAM) proteins. In addition, autoant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e5bd8abe02c4c15e9d972101b70367
http://hdl.handle.net/2445/187073
http://hdl.handle.net/2445/187073
