Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Eivind Heggernes, Ask"'
Autor:
Benjamin H. Goldenson, Huang Zhu, YunZu Michele Wang, Naveen Heragu, Davide Bernareggi, Alessa Ruiz-Cisneros, Andres Bahena, Eivind Heggernes Ask, Hanna Julie Hoel, Karl-Johan Malmberg, Dan S. Kaufman
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Natural killer (NK) cells derived or isolated from different sources have been gaining in importance for cancer therapies. In this study, we evaluate and compare key characteristics between NK cells derived or isolated from umbilical cord blood, umbi
Externí odkaz:
https://doaj.org/article/ca698d959f744c399748b33965dfb205
Autor:
Jodie P. Goodridge, Benedikt Jacobs, Michelle L. Saetersmoen, Dennis Clement, Quirin Hammer, Trevor Clancy, Ellen Skarpen, Andreas Brech, Johannes Landskron, Christian Grimm, Aline Pfefferle, Leonardo Meza-Zepeda, Susanne Lorenz, Merete Thune Wiiger, William E. Louch, Eivind Heggernes Ask, Lisa L. Liu, Vincent Yi Sheng Oei, Una Kjällquist, Sten Linnarsson, Sandip Patel, Kjetil Taskén, Harald Stenmark, Karl-Johan Malmberg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Natural killer (NK) cells are functionally calibrated against self MHC during a process termed education. Here the authors show that NK cell education is associated with the accumulation of dense-core secretory lysosomes for expedited release of gran
Externí odkaz:
https://doaj.org/article/05087ace24334bc9a23a8959b77fbf46
Autor:
Aline Pfefferle, Benedikt Jacobs, Herman Netskar, Eivind Heggernes Ask, Susanne Lorenz, Trevor Clancy, Jodie P. Goodridge, Ebba Sohlberg, Karl-Johan Malmberg
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2284-2294.e4 (2019)
Summary: Natural killer (NK) cell repertoires are made up of phenotypically distinct subsets with different functional properties. The molecular programs involved in maintaining NK cell repertoire diversity under homeostatic conditions remain elusive
Externí odkaz:
https://doaj.org/article/ad2e3435aa40408692c349db85705659
Autor:
Ebba, Sohlberg, Aline, Pfefferle, Eivind, Heggernes Ask, Astrid, Tschan-Plessl, Benedikt, Jacobs, Herman, Netskar, Susanne, Lorenz, Minoru, Kanaya, Mizuha, Kosugi-Kanaya, Stephan, Meinke, Anette, Mörtberg, Petter, Höglund, Mikael, Sundin, Göran, Carlsson, Jan, Palmblad, Karl-Johan, Malmberg
Publikováno v:
Blood. 139(5)
Neutrophils have been thought to play a critical role in terminal differentiation of NK cells. Whether this effect is direct or a consequence of global immune changes with effects on NK-cell homeostasis remains unknown. In this study, we used high-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1abe7b29d8e3d8207e1a16be97c30801
https://pubmed.ncbi.nlm.nih.gov/34699594
https://pubmed.ncbi.nlm.nih.gov/34699594
Autor:
Johan K. Sandberg, Christopher Maucourant, Kristoffer Strålin, Soo Aleman, Iva Filipovic, Jonas Klingström, Marcus Buggert, Olav Rooyackers, Jakob Michaëlsson, Nicole Marquardt, Hans-Gustaf Ljunggren, Björn Reinius, Ryan M. Hull, Niklas K. Björkström, Eivind Heggernes Ask, Demi Brownlie, Martin Cornillet, Antonio Lentini, Angelica Cuapio, Quirin Hammer, Laura Hertwig, Benedikt Strunz, Lars Eriksson, Alvaro Haroun-Izquierdo, Elin Folkesson, Andrea Ponzetta, Karl-Johan Malmberg, Marie Schaffer
Publikováno v:
Science Immunology
The NK cell activation landscape in acute SARS-CoV-2 infection is associated with COVID-19 disease severity.
Activated NK cells in severe COVID-19 Natural killer (NK) cells are cytotoxic lymphocytes that provide innate immune defense against vir
Activated NK cells in severe COVID-19 Natural killer (NK) cells are cytotoxic lymphocytes that provide innate immune defense against vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7ac31c02d53d958390a341914d2d67
https://doi.org/10.1126/sciimmunol.abd6832
https://doi.org/10.1126/sciimmunol.abd6832
Autor:
Ryan M. Hull, Niklas K. Björkström, Andrea Ponzetta, Marcus Buggert, Benedikt Strunz, Quirin Hammer, Laura Hertwig, Olav Rooyackers, Johan K. Sandberg, Björn Reinius, Hans-Gustaf Ljunggren, Elin Folkesson, Antonio Lentini, Martin Cornillet, Christopher Maucourant, Alvaro Haroun-Izquierdo, Jonas Klingström, Angelica Cuapio Gomez, Jakob Michaëlsson, Soo Aleman, Iva Filipovic, Demi Brownlie, Eivind Heggernes Ask, Karl-Johan Malmberg, Nicole Marquardt, Kristoffer Strålin, Lars Eriksson, Marie Schaffer
Understanding innate immune responses in COVID-19 is important for deciphering mechanisms of host responses and interpreting disease pathogenesis. Natural killer (NK) cells are innate effector lymphocytes that respond to acute viral infections, but m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd2ca4e459f03fefd8d1094e5ec0e4de
https://doi.org/10.1101/2020.07.07.20148478
https://doi.org/10.1101/2020.07.07.20148478
Autor:
Eivind Heggernes, Ask, Astrid, Tschan-Plessl, Thea Johanne, Gjerdingen, Michelle Lu, Sætersmoen, Hanna Julie, Hoel, Merete Thune, Wiiger, Johanna, Olweus, Björn E, Wahlin, Ole Christian, Lingjærde, Amir, Horowitz, Amanda F, Cashen, Marcus, Watkins, Todd A, Fehniger, Harald, Holte, Arne, Kolstad, Karl-Johan, Malmberg
Publikováno v:
Med (New York, N.Y.). 2(2)
Current prognostic variables can only partly explain the large outcome heterogeneity in diffuse large B cell lymphoma (DLBCL). We aimed to investigate the utility of systems-level protein and immune repertoire profiling for outcome prognostication in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22239e0fda4667412dbb3b8589cb6002
https://pubmed.ncbi.nlm.nih.gov/35590201
https://pubmed.ncbi.nlm.nih.gov/35590201
Autor:
Robert Blum, Karl-Johan Malmberg, Davide Bernareggi, Kun-Liang Guan, Huang Zhu, Chengsheng Wu, Zhipeng Meng, Zhengming Wu, Hanna Julie Hoel, Eivind Heggernes Ask, Dan S. Kaufman
Publikováno v:
Cell Stem Cell
Cytokine-inducible SH2-containing protein (CIS; encoded by the gene CISH) is a key negative regulator of interleukin-15 (IL-15) signaling in natural killer (NK) cells. Here, we develop human CISH-knockout (CISH-/-) NK cells using an induced pluripote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21faae47f90476627d293cf826d6db6a
https://pubmed.ncbi.nlm.nih.gov/32531207
https://pubmed.ncbi.nlm.nih.gov/32531207
Autor:
Jan Palmblad, Mikael Sundin, Astrid Tschan-Plessl, Goran Karlsson, Ebba Sohlberg, Petter Höglund, Karl-Johan Malmberg, Benedikt Jacobs, Aline Pfefferle, Suzanne Lorenz, Stephan Meinke, Eivind Heggernes Ask
Publikováno v:
Blood. 136:24-25
Neutrophils are innate cells that have been suggested to play a critical role in terminal differentiation of NK cells. Whether this is a direct effect or a consequence of global immune changes with effects on NK cell homeostasis remains unknown. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cbe25ca2c9db903add9b1314eb83f99
https://doi.org/10.1182/blood-2020-141981
https://doi.org/10.1182/blood-2020-141981
Autor:
Marianna Vincenti, Dennis Clement, Eivind Heggernes Ask, Merete Thune Wiiger, Hanna Julie Hoel, Magdalena Winiarska, Daniel Alfredo Palacios, Karl-Johan Malmberg, Radoslaw Zagozdzon, Mieszko Lachota
Publikováno v:
Blood. 136:24-25
Natural Killer (NK) cells play an essential role in cancer surveillance and have a unique capability of spontaneous cytotoxicity against cancer cells. The human NK cell repertoire is functionally diversified through a tightly regulated differentiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fde308c6212ca100659c84765ab6a761
https://doi.org/10.1182/blood-2020-140944
https://doi.org/10.1182/blood-2020-140944