Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Eivind A B, Undheim"'
Autor:
Vanessa Schendel, Carsten H. G. Müller, Matthes Kenning, Michael Maxwell, Ronald A. Jenner, Eivind A. B. Undheim, Andy Sombke
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Background Evolution of novelty is a central theme in evolutionary biology, yet studying the origins of traits with an apparently discontinuous origin remains a major challenge. Venom systems are a well-suited model for the study of this phe
Externí odkaz:
https://doaj.org/article/2d288812cb5046b49556da5e9cb77e12
Autor:
Samuel D. Robinson, Jennifer R. Deuis, Axel Touchard, Angelo Keramidas, Alexander Mueller, Christina I. Schroeder, Valentine Barassé, Andrew A. Walker, Nina Brinkwirth, Sina Jami, Elsa Bonnafé, Michel Treilhou, Eivind A. B. Undheim, Justin O. Schmidt, Glenn F. King, Irina Vetter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Stings of certain ant species (Hymenoptera: Formicidae) can cause intense, long-lasting nociception. Here we show that the major contributors to these symptoms are venom peptides that modulate the activity of voltage-gated sodium (NaV) chann
Externí odkaz:
https://doaj.org/article/06020d0862264dda9a11dae6073fc211
Autor:
Lauren M. Ashwood, Khaled A. Elnahriry, Zachary K. Stewart, Thomas Shafee, Muhammad Umair Naseem, Tibor G. Szanto, Chloé A. van der Burg, Hayden L. Smith, Joachim M. Surm, Eivind A. B. Undheim, Bruno Madio, Brett R. Hamilton, Shaodong Guo, Dorothy C. C. Wai, Victoria L. Coyne, Matthew J. Phillips, Kevin J. Dudley, David A. Hurwood, Gyorgy Panyi, Glenn F. King, Ana Pavasovic, Raymond S. Norton, Peter J. Prentis
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-25 (2023)
Abstract Background The ShK toxin from Stichodactyla helianthus has established the therapeutic potential of sea anemone venom peptides, but many lineage-specific toxin families in Actiniarians remain uncharacterised. One such peptide family, sea ane
Externí odkaz:
https://doaj.org/article/21a4debffec04564ae9a29b4a8776746
Autor:
Michael J. Maxwell, Chris Thekkedam, Cedric Lamboley, Yanni K.-Y. Chin, Theo Crawford, Jennifer J. Smith, Junyu Liu, Xinying Jia, Irina Vetter, Derek R. Laver, Bradley S. Launikonis, Angela Dulhunty, Eivind A. B. Undheim, Mehdi Mobli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Insect toxins with tandem repeats of neurotoxin domains have been found with enhanced receptor avidity. Here, the authors describe a bivalent toxin from remipede venom that targets ryanodine receptors, a rare target for animal venoms.
Externí odkaz:
https://doaj.org/article/ecfef30c1c5e4dc1ab651ec6f5d81576
Autor:
Samuel D. Robinson, Vanessa Schendel, Christina I. Schroeder, Sarah Moen, Alexander Mueller, Andrew A. Walker, Naomi McKinnon, G. Gregory Neely, Irina Vetter, Glenn F. King, Eivind A. B. Undheim
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Eusociality is widely considered to evolve through kin selection, where the reproductive success of an individual’s close relative is favored at the expense of its own. High genetic relatedness is thus considered a prerequisite
Externí odkaz:
https://doaj.org/article/d7dcdb11b76c4cd2a50d33482f7f16f4
Autor:
Taline D. Kazandjian, Brett R. Hamilton, Samuel D. Robinson, Steven R. Hall, Keirah E. Bartlett, Paul Rowley, Mark C. Wilkinson, Nicholas R. Casewell, Eivind A. B. Undheim
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Venoms are ecological innovations that have evolved numerous times, on each occasion accompanied by the co-evolution of specialised morphological and behavioural characters for venom production and delivery. The close evolutionary
Externí odkaz:
https://doaj.org/article/b91d692a5baf448f9a884c4156fe0436
Autor:
Daiane Laise da Silva, Rodrigo Valladão, Emidio Beraldo-Neto, Guilherme Rabelo Coelho, Oscar Bento da Silva Neto, Hugo Vigerelli, Adriana Rios Lopes, Brett R. Hamilton, Eivind A. B. Undheim, Juliana Mozer Sciani, Daniel Carvalho Pimenta
Publikováno v:
Marine Drugs, Vol 21, Iss 9, p 481 (2023)
Sea anemones are known to produce a diverse array of toxins with different cysteine-rich peptide scaffolds in their venoms. The serine peptidase inhibitors, specifically Kunitz inhibitors, are an important toxin family that is believed to function as
Externí odkaz:
https://doaj.org/article/347b74902ff947a2b73b70cd05de9186
Autor:
Eivind A. B. Undheim, Ronald A. Jenner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Animal venoms have evolved many times primarily by recruitment of endogenous proteins with physiological functions. Undheim and Jenner find that centipede venoms have recruited at least five gene families from bacterial and fungal donors, involving a
Externí odkaz:
https://doaj.org/article/dec89fedfc924d94b04406afa7b516fa
Autor:
Daniel Dashevsky, Kate Baumann, Eivind A. B. Undheim, Amanda Nouwens, Maria P. Ikonomopoulou, Justin O. Schmidt, Lilin Ge, Hang Fai Kwok, Juanita Rodriguez, Bryan G. Fry
Publikováno v:
Toxins, Vol 15, Iss 3, p 224 (2023)
Aculeate hymenopterans use their venom for a variety of different purposes. The venom of solitary aculeates paralyze and preserve prey without killing it, whereas social aculeates utilize their venom in defence of their colony. These distinct applica
Externí odkaz:
https://doaj.org/article/26e0f98f3b214328a864d673ba9e1ef3
Autor:
Dongchen An, Ernesto Lopes Pinheiro-Junior, László Béress, Irina Gladkikh, Elena Leychenko, Eivind A. B. Undheim, Steve Peigneur, Jan Tytgat
Publikováno v:
Marine Drugs, Vol 20, Iss 2, p 140 (2022)
(1) Background: G protein-coupled inward-rectifier potassium (GIRK) channels, especially neuronal GIRK1/2 channels, have been the focus of intense research interest for developing drugs against brain diseases. In this context, venom peptides that sel
Externí odkaz:
https://doaj.org/article/c30e3f24ff8f44c7821bc2c20af3c4bc