Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Eiton Kaltgrad"'
Autor:
Katherine Doores, Sheng-Kai Wang, Eiton Kaltgrad, James C. Paulson, Dennis R. Burton, Cheng-Yuan Huang, M. G. Finn, Ralph Pantophlet, Rena D. Astronomo, Chi-Huey Wong, Andrew K. Udit
Publikováno v:
Chemistry & Biology. 17(4):357-370
Summary The broadly neutralizing antibody 2G12 recognizes a conserved cluster of high-mannose glycans on the surface envelope spike of HIV, suggesting that the "glycan shield" defense of the virus can be breached and may, under the right circumstance
Autor:
Carlos F. Barbas, Lian-Sheng Li, Subhash C. Sinha, Richard A. Lerner, Shin-ichi Watanabe, Christoph Rader, Eiton Kaltgrad, Fujie Tanaka
Publikováno v:
Chemistry - A European Journal. 10:5467-5472
Prodrugs of potent aldehyde analogues of the anticancer drug doxorubicin (Dox) were synthesized. These prodrugs were efficiently activated by antibody 93F3 and no drug formation was observed in the absence of 93F3 in either phosphate buffered saline
Publikováno v:
Chemistry & Biology. 9:805-811
Cowpea mosaic virus (CPMV) can be isolated in gram quantities, possesses a structure that is known to atomic resolution, and is quite stable. It is therefore of potential use as a molecular entity in synthesis, particularly as a building block on the
Autor:
Eiton Kaltgrad, Darryl J. Bornhop, Mark L. Wolfenden, Amanda Kussrow, M. G. Finn, Mary J. Cloninger
Publikováno v:
Analytical chemistry. 81(12)
Carbohydrate-protein binding is important to many areas of biochemistry. Here, backscattering interferometry (BSI) has been shown to be a convenient and sensitive method for obtaining quantitative information about the strengths and selectivities of
Publikováno v:
Bioconjugate chemistry. 16(6)
Successful purification of biological molecules by affinity chromatography requires the attachment of desired ligands to biocompatible chromatographic supports. The Cu(I)-catalyzed cycloaddition of azides and alkynes-the premier example of "click che
Publikováno v:
Chemistrybiology. 9(7)
Cowpea mosaic virus (CPMV) can be isolated in gram quantities, possesses a structure that is known to atomic resolution, and is quite stable. It is therefore of potential use as a molecular entity in synthesis, particularly as a building block on the
Publikováno v:
Journal of the American Chemical Society. 130:4578-4579
Glycans arrayed on the exterior of virus particles were used as substrates for glycosyltransferase reactions to build di- and trisaccharides from the virus surface. The resulting particles exhibited tight and specific associations with cognate recept
Autor:
M. G. Finn, K. Barry Sharpless, Eiton Kaltgrad, Michael Malkoch, Valery V. Fokin, Jasmine N. Hunt, Peng Wu, Craig J. Hawker, Robert Vestberg
Publikováno v:
Chemical Communications. :5775
Unsymmetrical dendrimers, containing both mannose binding units and coumarin fluorescent units, have been prepared using click chemistry and shown to be highly efficient, dual-purpose recognition/detection agents for the inhibition of hemagglutinatio
Publikováno v:
Chemical Communications. :4315
The Cu(I)-catalyzed ATRP and azide-alkyne cycloaddition reactions together provide a versatile method for the synthesis of end-functionalized glycopolymers and their attachment to a suitably modified viral protein scaffold.
Autor:
Peng Wu, Michael Malkoch, Jasmine N. Hunt, Robert Vestberg, Eiton Kaltgrad, M. G. Finn, Valery V. Fokin, K. Barry Sharpless, Craig J. Hawker
Publikováno v:
Chemical Communications; Nov2005, Vol. 2005 Issue 46, p5775-5777, 3p