Alternative splicing of MALT1 controls signalling and activation of CD4(+) T cells.

Autor: Meininger I; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany., Griesbach RA; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.; Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstrasse 55, 72770 Reutlingen, Germany., Hu D; Research Unit Molecular Immune Regulation, Helmholtz Zentrum München-German Research Center for Environmental Health, Marchioninistrsse 25, 81377 München, Germany.; Institute for Immunology, Biomedical Center Munich, LMU Munich, Grosshaderner Strsse 9, 82152 Martinsried, Germany., Gehring T; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany., Seeholzer T; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany., Bertossi A; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany., Kranich J; Institute for Immunology, Biomedical Center Munich, LMU Munich, Grosshaderner Strsse 9, 82152 Martinsried, Germany., Oeckinghaus A; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany., Eitelhuber AC; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany., Greczmiel U; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany., Gewies A; Institut für Klinische Chemie und Pathobiochemie, Klinikum rechts der Isar, Technische Universität München, 81675 München, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Schmidt-Supprian M; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; Molecular Immunopathology &Signal Transduction, III. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, 81675 München, Germany., Ruland J; Institut für Klinische Chemie und Pathobiochemie, Klinikum rechts der Isar, Technische Universität München, 81675 München, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; German Center for Infection Research (DZIF), partner site Munich, 81675 München, Germany., Brocker T; Institute for Immunology, Biomedical Center Munich, LMU Munich, Grosshaderner Strsse 9, 82152 Martinsried, Germany., Heissmeyer V; Research Unit Molecular Immune Regulation, Helmholtz Zentrum München-German Research Center for Environmental Health, Marchioninistrsse 25, 81377 München, Germany.; Institute for Immunology, Biomedical Center Munich, LMU Munich, Grosshaderner Strsse 9, 82152 Martinsried, Germany., Heyd F; Free University Berlin, Institute of Chemistry and Biochemistry, RNA Biochemistry, Takustrasse 6, 14195 Berlin, Germany., Krappmann D; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.

Publikováno v: Nature communications [Nat Commun] 2016 Apr 12; Vol. 7, pp. 11292. Date of Electronic Publication: 2016 Apr 12.

Activity-based probes for detection of active MALT1 paracaspase in immune cells and lymphomas.

Autor: Eitelhuber AC; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München - German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany., Vosyka O; Lehrstuhl für Chemie der Biopolymere, Technische Universität München, Weihenstephaner Berg 3, 85354 Freising, Germany., Nagel D; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München - German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany., Bognar M; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München - German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany., Lenze D; Department of Pathology, Charité - University Medicine Berlin, Hindenburgdamm 30, 12200 Berlin, Germany., Lammens K; Department of Biochemistry, Gene Center, Ludwig-Maximilian University, Feodor-Lynen-Strasse 25, 81377 Munich, Germany., Schlauderer F; Department of Biochemistry, Gene Center, Ludwig-Maximilian University, Feodor-Lynen-Strasse 25, 81377 Munich, Germany., Hlahla D; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München - German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany., Hopfner KP; Department of Biochemistry, Gene Center, Ludwig-Maximilian University, Feodor-Lynen-Strasse 25, 81377 Munich, Germany., Lenz G; Department of Medicine A, Translational Oncology, Albert-Schweitzer Campus 1, University Hospital Muenster, 48149 Muenster, Germany., Hummel M; Department of Pathology, Charité - University Medicine Berlin, Hindenburgdamm 30, 12200 Berlin, Germany., Verhelst SH; Lehrstuhl für Chemie der Biopolymere, Technische Universität München, Weihenstephaner Berg 3, 85354 Freising, Germany., Krappmann D; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München - German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany. Electronic address: daniel.krappmann@helmholtz-muenchen.de.

Publikováno v: Chemistry & biology [Chem Biol] 2015 Jan 22; Vol. 22 (1), pp. 129-38. Date of Electronic Publication: 2014 Dec 31.

AIP augments CARMA1-BCL10-MALT1 complex formation to facilitate NF-κB signaling upon T cell activation.

Autor: Schimmack G, Eitelhuber AC, Vincendeau M, Demski K, Shinohara H, Kurosaki T, Krappmann D

Publikováno v: Cell communication and signaling : CCS [Cell Commun Signal] 2014 Jul 22; Vol. 12, pp. 49. Date of Electronic Publication: 2014 Jul 22.

Dephosphorylation of Carma1 by PP2A negatively regulates T-cell activation.

Autor: Eitelhuber AC; Department of Cellular Signal Integration, Helmholtz Zentrum München-German Research Center for Environmental Health, Institute of Toxicology, Neuherberg, Germany., Warth S, Schimmack G, Düwel M, Hadian K, Demski K, Beisker W, Shinohara H, Kurosaki T, Heissmeyer V, Krappmann D

Publikováno v: The EMBO journal [EMBO J] 2011 Feb 02; Vol. 30 (3), pp. 594-605. Date of Electronic Publication: 2010 Dec 14.