Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Eitaro Hiejima"'
Autor:
Takayuki Miyamoto, Yoshitaka Honda, Kazushi Izawa, Nobuo Kanazawa, Saori Kadowaki, Hidenori Ohnishi, Masakazu Fujimoto, Naotomo Kambe, Naoya Kase, Takeshi Shiba, Yasuo Nakagishi, Shuji Akizuki, Kosaku Murakami, Masahiro Bamba, Yutaka Nishida, Ayano Inui, Tomoo Fujisawa, Daisuke Nishida, Naomi Iwata, Yoshikazu Otsubo, Shingo Ishimori, Momoko Nishikori, Kiminobu Tanizawa, Tomoyuki Nakamura, Takeshi Ueda, Yoko Ohwada, Yu Tsuyusaki, Masaki Shimizu, Takasuke Ebato, Kousho Iwao, Akiharu Kubo, Toshinao Kawai, Tadashi Matsubayashi, Tatsuhiko Miyazaki, Tomohiro Kanayama, Masahiko Nishitani-Isa, Hiroshi Nihira, Junya Abe, Takayuki Tanaka, Eitaro Hiejima, Satoshi Okada, Osamu Ohara, Megumu K. Saito, Junko Takita, Ryuta Nishikomori, Takahiro Yasumi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
PurposeUpregulation of type I interferon (IFN) signaling has been increasingly detected in inflammatory diseases. Recently, upregulation of the IFN signature has been suggested as a potential biomarker of IFN-driven inflammatory diseases. Yet, it rem
Externí odkaz:
https://doaj.org/article/5700023cf0774dc68dac5c83825a3a61
Autor:
Mariko Aoki, Kazushi Izawa, Takayuki Tanaka, Yoshitaka Honda, Takeshi Shiba, Yukako Maeda, Takayuki Miyamoto, Keisuke Okamoto, Masahiko Nishitani-Isa, Hiroshi Nihira, Kohsuke Imai, Junko Takita, Ryuta Nishikomori, Eitaro Hiejima, Takahiro Yasumi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Familial Mediterranean fever (FMF) is a hereditary, autoinflammatory disease that causes recurrent fever, arthritis, and serositis. The diagnosis of FMF is based on the presentation of typical clinical symptoms and the Mediterranean fever gene (MEFV)
Externí odkaz:
https://doaj.org/article/de636ce9fe18427db2a7afcc9eaf72bd
Autor:
Koji Nakajima, Eitaro Hiejima, Hiroshi Nihira, Kentaro Kato, Yoshitaka Honda, Kazushi Izawa, Naoko Kawabata, Itaru Kato, Eri Ogawa, Mari Sonoda, Tatsuya Okamoto, Hideaki Okajima, Takahiro Yasumi, Junko Takita
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Hepatic manifestations of Epstein-Barr virus (EBV) infection are relatively common, mild, and self-limiting. Although fulminant hepatic failure has been reported in a few cases, the contributing factors are unclear. This report discusses a pediatric
Externí odkaz:
https://doaj.org/article/c6d833a3b68648ffa7d1d6a96bacc5a5
Autor:
Hiroki Mukoyama, Junko Takita, Takayuki Miyamoto, Takayuki Tanaka, Osamu Ohara, Yoshitaka Honda, Haruna Nakaseko, Takeshi Shiba, Keisuke Nishimura, Masahiko Isa-Nishitani, Hirofumi Shibata, Eitaro Hiejima, Yukako Maeda, Kazushi Izawa, Hiroshi Nihira, Takahiro Yasumi, Ryuta Nishikomori
Publikováno v:
Journal of Clinical Immunology. 41:1187-1197
Pathogenic MEFV variants cause pyrin-associated autoinflammatory diseases (PAADs), which include familial Mediterranean fever (FMF), FMF-like disease, and pyrin-associated autoinflammation with neutrophilic dermatosis (PAAND). The diagnosis of PAADs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1ce852d10451c31c1bd6afd5bc40511
https://doi.org/10.1007/s10875-021-01021-7
https://doi.org/10.1007/s10875-021-01021-7
Autor:
Dan Tomomasa, Eitaro Hiejima, Takayuki Miyamoto, Kay Tanita, Masaki Matsuoka, Daiki Niizato, Noriko Mitsuiki, Takeshi Isoda, Takahiro Yasumi, Menno C. van Zelm, Tomohiro Morio, Hirokazu Kanegane
Publikováno v:
Clinical immunology (Orlando, Fla.). 242
Familial hemophagocytic lymphohistiocytosis type 3 is a fatal inborn error of immunity due to abnormal cytotoxic activity of T and NK cells and is caused by variants in UNC13D, which encodes Munc13-4. One published case was reported to carry a tandem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d565f80c4dccb3199c5190083015eae1
https://pubmed.ncbi.nlm.nih.gov/36041693
https://pubmed.ncbi.nlm.nih.gov/36041693
Autor:
Atsushi Kitani, Liming Mao, Kim Montgomery-Recht, Wenchang Zhou, Adrian Wiestner, Ivan J. Fuss, Eitaro Hiejima, Warren Strober
Publikováno v:
J Clin Invest
Bruton tyrosine kinase (BTK) is present in a wide variety of cells and may thus have important non–B cell functions. Here, we explored the function of this kinase in macrophages with studies of its regulation of the NLR family, pyrin domain–conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5065c11282ca001a45a6d2d7dd148c30
https://doi.org/10.1172/jci128322
https://doi.org/10.1172/jci128322
Autor:
Masahiko Nishitani-Isa, Kojiro Mukai, Yoshitaka Honda, Hiroshi Nihira, Takayuki Tanaka, Hirofumi Shibata, Kumi Kodama, Eitaro Hiejima, Kazushi Izawa, Yuri Kawasaki, Mitsujiro Osawa, Yu Katata, Sachiko Onodera, Tatsuya Watanabe, Takashi Uchida, Shigeo Kure, Junko Takita, Osamu Ohara, Megumu K. Saito, Ryuta Nishikomori, Tomohiko Taguchi, Yoji Sasahara, Takahiro Yasumi
Publikováno v:
The Journal of experimental medicine. 219(6)
Mutations in the C-terminal region of the CDC42 gene cause severe neonatal-onset autoinflammation. Effectiveness of IL-1β–blocking therapy indicates that the pathology involves abnormal inflammasome activation; however, the mechanism underlying au
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57052104bfac1631446914bbc55c141e
https://pubmed.ncbi.nlm.nih.gov/35482294
https://pubmed.ncbi.nlm.nih.gov/35482294
Autor:
Hirofumi Shibata, Tomohiro Tanaka, Megumu K. Saito, K. Kodama, Kojiro Mukai, Junko Takita, Osamu Ohara, Takahiro Yasumi, Ryuta Nishikomori, Mitsujiro Osawa, Yoshitaka Honda, S. Onodera, T. Watanabe, Y. Katata, Hiroshi Nihira, Kazushi Izawa, Yoji Sasahara, Masahiko Nishitani-Isa, Eitaro Hiejima, Yuri Kawasaki, Shigeo Kure, Tomohiko Taguchi
Mutations in the C-terminal region of the CDC42 gene cause severe neonatal-onset autoinflammation. Elevated levels of serum IL-18 in patients and effectiveness of IL-1β-blocking therapy indicate that the pathology involves abnormal inflammasome acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57b1675b389dc421c064849683581da4
https://doi.org/10.1101/2021.09.03.458902
https://doi.org/10.1101/2021.09.03.458902
Autor:
Yuya Muramoto, Hiroshi Nihira, Masahiro Shiokawa, Kazushi Izawa, Eitaro Hiejima, Hiroshi Seno, Takeshi Kuwada, Katsuhiro Arai, Takahiro Kudo, Itaru Iwama, Tatsuki Mizuochi, Tsuyoshi Sogo, Emiri Kaji, Takehiko Doi, Toshinao Kawai, Masami Inoue, Yoji Sasahara, Hidenori Ohnishi, Satoshi Okada, Hirokazu Kanegane, Ryuta Nishikomori, Hirotaka Shimizu, Ichiro Takeuchi, Natsuki Ito, Ryosuke Yasuda, Ayano Inui, Yuri Etani, Hajime Yamazaki, Yoshihiro Nishikawa, Yoshitaka Honda, Norimitsu Uza, Junko Takita, Tsutomu Chiba, Takahiro Yasumi
Publikováno v:
Gastroenterology. 163:1094-1097.e14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0c0eb967bebae4f95eaf5615130d42
https://doi.org/10.1053/j.gastro.2022.06.026
https://doi.org/10.1053/j.gastro.2022.06.026
Autor:
Yoshitaka, Honda, Yukako, Maeda, Kazushi, Izawa, Takeshi, Shiba, Takayuki, Tanaka, Haruna, Nakaseko, Keisuke, Nishimura, Hiroki, Mukoyama, Masahiko, Isa-Nishitani, Takayuki, Miyamoto, Hiroshi, Nihira, Hirofumi, Shibata, Eitaro, Hiejima, Osamu, Ohara, Junko, Takita, Takahiro, Yasumi, Ryuta, Nishikomori
Publikováno v:
Journal of clinical immunology. 41(6)
Pathogenic MEFV variants cause pyrin-associated autoinflammatory diseases (PAADs), which include familial Mediterranean fever (FMF), FMF-like disease, and pyrin-associated autoinflammation with neutrophilic dermatosis (PAAND). The diagnosis of PAADs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::628ea4a177907c73decfcaf0fcd9f9cf
https://pubmed.ncbi.nlm.nih.gov/33733382
https://pubmed.ncbi.nlm.nih.gov/33733382