Development and Initial Validation of the Macrophage Activation Syndrome/Primary Hemophagocytic Lymphohistiocytosis Score, a Diagnostic Tool that Differentiates Primary Hemophagocytic Lymphohistiocytosis from Macrophage Activation Syndrome

Autor: Abinun, Mario, Aggarwal, Amita, Akikusa, Jonathan, Al-Mayouf, Sulaiman, Alessio, Maria, Anton, Jordi, Apaz, Maria Teresa, Astigarraga, Itziar, Avcin, Tadej, Ayaz, Nuray Aktay, Barone, Patrizia, Bica, Bianca, Bolt, Isabel, Bovis, Francesca, Breda, Luciana, Chasnyk, Vyacheslav, Cimaz, Rolando, Corona, Fabrizia, Cron, Randy Q., Cuttica, Ruben, Davì, Sergio, Davidsone, Zane, De Cunto, Carmen, De Inocencio, Jaime, Demirkaya, Erkan, Eisenstein, Eli M., Enciso, Sandra, Espada, Graciela, Fischbach, Michel, Frosch, Michael, Gallizzi, Romina, Gamir, Maria Luz, Gao, Yi-Jin, Griffin, Thomas, Grom, Alexei, Hashad, Soad, Hennon, Teresa, Henter, Jan-Inge, Horne, AnnaCarin, Horneff, Gerd, Huasong, Zeng, Huber, Adam, Ilowite, Norman, Insalaco, Antonella, Ioseliani, Maka, Jeng, Michael, Kapović, Agneza Marija, Kasapcopur, Ozgur, Khubchandani, Raju, Kitoh, Toshiyuki, Koné-Paut, Isabelle, de Oliveira, Sheila Knupp Feitosa, Lattanzi, Bianca, Lehmberg, Kai, Lepore, Loredana, Li, Caifeng, Lipton, Jeffrey M., Magni-Manzoni, Silvia, Maritsi, Despoina, Martini, Alberto, McCurdy, Deborah, Merino, Rosa, Micalizzi, Concetta, Miettunen, Paivi, Minoia, Francesca, Mulaosmanovic, Velma, Nichols, Kim E., Nielsen, Susan, Ozen, Seza, Pal, Priyankar, Prahalad, Sampath, Ravelli, Angelo, Rigante, Donato, Rumba-Rozenfelde, Ingrida, Ruperto, Nicolino, Russo, Ricardo, Magalhães, Claudia Saad, Sanner, Helga, Sewairi, Wafaa Mohamed Saad, Shenoi, Susan, Artur Silva, Clovis, Stanevicha, Valda, Sterba, Gary, Stine, Kimo C., Susic, Gordana, Sztajnbok, Flavio, Takei, Syuji, Trauzeddel, Ralf, Tsitsami, Elena, Unsal, Erbil, Uziel, Yosef, Vougiouka, Olga, Wallace, Carol A., Weaver, Lehn, E. Weiss, Jennifer, Weitzman, Sheila, Wouters, Carine, Wulffraat, Nico, Zletni, Mabruka, Arico, Maurizio, Egeler, R. Maarten, Filipovich, Alexandra H., Gadner, Helmut, Imashuku, Shinsaku, Janka, Gritta, Ladisch, Stephan, McClain, Ken L., Webb, David

Publikováno v: In The Journal of Pediatrics October 2017 189:72-78

Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19

Autor: Sacco, Keith, Castagnoli, Riccardo, Vakkilainen, Svetlana, Liu, Can, Delmonte, Ottavia M., Oguz, Cihan, Kaplan, Ian M., Alehashemi, Sara, Burbelo, Peter D., Bhuyan, Farzana, de Jesus, Adriana A., Dobbs, Kerry, Rosen, Lindsey B., Cheng, Aristine, Shaw, Elana, Vakkilainen, Mikko S., Pala, Francesca, Lack, Justin, Zhang, Yu, Fink, Danielle L, Oikonomou, Vasileios, Snow, Andrew L., Dalgard, Clifton L., Chen, Jinguo, Sellers, Brian A., Sanchez, Gina A. Montealegre, Barron, Karyl, Rey-Jurado, Emma, Vial, Cecilia, Poli, Maria Cecilia, Licari, Amelia, Montagna, Daniela, Marseglia, Gian Luigi, Licciardi, Francesco, Ramenghi, Ugo, Discepolo, Valentina, Vecchio, Andrea Lo, Guarino, Alfredo, Eisenstein, Eli M., Imberti, Luisa, Sottini, Alessandra, Biondi, Andrea, Mató, Sayonara, Gerstbacher, Dana, Truong, Meng, Stack, Michael A., Magliocco, Mary, Bosticardo, Marita, Kawai, Tomoki, Danielson, Jeffrey J., Hulett, Tyler, Askenazi, Manor, Hu, Shaohui, Cohen, Jeffrey I., Su, Helen C., Kuhns, Douglas B., Lionakis, Michail S., Snyder, Thomas M., Holland, Steven M., Goldbach-Mansky, Raphaela, Tsang, John S., Notarangelo, Luigi D.

Publikováno v: Nat Med

Transcriptomic, proteomic and immune repertoire profiling reveals distinct peripheral features of MIS-C and pediatric COVID-19, including elevated soluble spike protein levels, more pronounced type II IFN-dependent gene expression and a higher B cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57428c283f6d50f5efddc9a7730771d
https://europepmc.org/articles/PMC9119950/

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Autoantibodies Against Proteins Previously Associated With Autoimmunity in Adult and Pediatric Patients With COVID-19 and Children With MIS-C

Autor: Burbelo, Peter D, Castagnoli, Riccardo, Shimizu, Chisato, Delmonte, Ottavia M, Dobbs, Kerry, Discepolo, Valentina, Lo Vecchio, Andrea, Guarino, Alfredo, Licciardi, Francesco, Ramenghi, Ugo, Rey-Jurado, Emma, Vial, Cecilia, Marseglia, Gian Luigi, Licari, Amelia, Montagna, Daniela, Rossi, Camillo, Montealegre Sanchez, Gina A, Barron, Karyl, Warner, Blake M, Chiorini, John A, Espinosa, Yazmin, Noguera, Loreani, Dropulic, Lesia, Truong, Meng, Gerstbacher, Dana, Mató, Sayonara, Kanegaye, John, Tremoulet, Adriana H, Pediatric Emergency Medicine Kawasaki Group, Eisenstein, Eli M, Su, Helen C, Imberti, Luisa, Poli, Maria Cecilia, Burns, Jane C, Notarangelo, Luigi D, Cohen, Jeffrey I

The antibody profile against autoantigens previously associated with autoimmune diseases and other human proteins in patients with COVID-19 or multisystem inflammatory syndrome in children (MIS-C) remains poorly defined. Here we show that 30% of adul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::de71091e2d50ccbe7e0ea7184d62ccf9
https://escholarship.org/uc/item/77f272db

Multiomics approach identifies novel age-, time- and treatment-related immunopathological signatures in MIS-C and pediatric COVID-19

Autor: Sacco, Keith, Castagnoli, Riccardo, Vakkilainen, Svetlana, Liu, Can, Delmonte, Ottavia M., Oguz, Cihan, Kaplan, Ian M., Alehashemi, Sara, Burbelo, Peter D., Bhuyan, Farzana, A. de Jesus, Adriana, Dobbs, Kerry, Rosen, Lindsey B., Cheng, Aristine, Shaw, Elana, Vakkilainen, Mikko S., Pala, Francesca, Lack, Justin, Zhang, Yu, Fink, Danielle L., Oikonomou, Vasileios, Snow, Andrew L., Dalgard, Clifton L., Chen, Jinguo, Sellers, Brian A., Montealegre Sanchez, Gina A., Barron, Karyl, Rey, Emma, Vial, Cecilia, Poli, Maria Cecilia, Licari, Amelia, Montagna, Daniela, Marseglia, Gian Luigi, Licciardi, Francesco, Ramenghi, Ugo, Discepolo, Valentina, Vecchio, Andrea Lo, Guarino, Alfredo, Eisenstein, Eli M., Imberti, Luisa, Sottini, Alessandra, Biondi, Andrea, Mató, Sayonara, Gertsbacher, Dana, Truong, Meng, Stack, Michael A., Magliocco, Mary, Bosticardo, Marita, Kawai, Tomoki, Danielson, Jeffrey J., Hulett, Tyler, Askenazi ,Manor, NIH, NIAID Immune Response to COVID Group, Chile, Chile MIS-C Group, Pavia, Pavia Pediatric COVID-19 Group, Cohen, Jeffrey I., Su, Helen C., Kuhns, Douglas B., Lionakis, Michail S., Snyder, Thomas M., Holland, Steven M., Goldbach-Mansky, Raphaela, Tsang, John S., Notarangelo, Luigi D.

This repository contains the CITE-Seq data set used in the manuscript titled "Multiomics approach identifies novel age-, time- and treatment-related immunopathological signatures in MIS-C and pediatric COVID-19". This data set is composed of the expr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d5cbefcf8f22ca3253dd39eb3496b3