Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Eisenstatt"'
Autor:
Eisenstatt, Jessica R.
Cells are regularly subjected to exogenous and endogenous processes that damage DNA which may result in double strand breaks (DSBs). Specialized sensor proteins recognize these breaks and trigger a cellular response leading to cell cycle arrest and/o
Externí odkaz:
http://rave.ohiolink.edu/etdc/view?acc_num=case1440417554
Autor:
Jessica R. Eisenstatt, Lars Boeckmann, Wei-Chun Au, Valerie Garcia, Levi Bursch, Josefina Ocampo, Michael Costanzo, Michael Weinreich, Robert A. Sclafani, Anastasia Baryshnikova, Chad L. Myers, Charles Boone, David J. Clark, Richard Baker, Munira A. Basrai
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 6, Pp 2057-2068 (2020)
The evolutionarily conserved centromeric histone H3 variant (Cse4 in budding yeast, CENP-A in humans) is essential for faithful chromosome segregation. Mislocalization of CENP-A to non-centromeric chromatin contributes to chromosomal instability (CIN
Externí odkaz:
https://doaj.org/article/18406182fbf848b19238234c13a0f3b1
Autor:
Wei-Chun Au, Tianyi Zhang, Prashant K Mishra, Jessica R Eisenstatt, Robert L Walker, Josefina Ocampo, Anthony Dawson, Jack Warren, Michael Costanzo, Anastasia Baryshnikova, Karin Flick, David J Clark, Paul S Meltzer, Richard E Baker, Chad Myers, Charles Boone, Peter Kaiser, Munira A Basrai
Publikováno v:
PLoS Genetics, Vol 16, Iss 2, p e1008597 (2020)
Restricting the localization of the histone H3 variant CENP-A (Cse4 in yeast, CID in flies) to centromeres is essential for faithful chromosome segregation. Mislocalization of CENP-A leads to chromosomal instability (CIN) in yeast, fly and human cell
Externí odkaz:
https://doaj.org/article/4a4e4d4931964e2b9c6fa1e904c0dd0e
Publikováno v:
F1000Research, Vol 7 (2018)
DNA double-strand breaks (DSBs) activate the DNA damage checkpoint machinery to pause or halt the cell cycle. Telomeres, the specific DNA-protein complexes at linear eukaryotic chromosome ends, are capped DSBs that do not activate DNA damage checkpoi
Externí odkaz:
https://doaj.org/article/0417e68b9cb641f0aeec88c8ad315a2a
Autor:
Eisenstatt, Jessica R.1, Boeckmann, Lars1, Wei-Chun Au1, Garcia, Valerie1, Bursch, Levi1, Ocampo, Josefina2, Costanzo, Michael3,4, Weinreich, Michael5, Sclafani, Robert A.6, Baryshnikova, Anastasia7, Myers, Chad L.8, Boone, Charles3,4, Clark, David J.2, Baker, Richard9, Basrai, Munira A.1 basraim@nih.gov
Publikováno v:
G3: Genes | Genomes | Genetics. Jun2020, Vol. 10 Issue 6, p2057-2068. 12p.
Akademický článek
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Autor:
Evelyn Suva, Jessica R. Eisenstatt, Wei-Chun Au, Michael Costanzo, Kentaro Ohkuni, Munira A. Basrai, Olivia Preston, Charles Boone, Loran Gliford
Publikováno v:
Genetics
Mislocalization of the centromeric histone H3 variant (Cse4 in budding yeast, CID in flies, CENP-A in humans) to noncentromeric regions contributes to chromosomal instability (CIN) in yeast, fly, and human cells. Overexpression and mislocalization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbbc3c3e6fbddcdb5eeaf51a8bcb81b
https://doi.org/10.1093/genetics/iyab033
https://doi.org/10.1093/genetics/iyab033
Autor:
Boeckmann, L., Au, W.-C., Bloom, K.S., Eisenstatt, J.R., Wood, H., Mishra, P.K., Sclafani, R.A., Weinreich, M., Stanton, J., Basrai, M.A., Thorpe, P.H.
Faithful chromosome segregation maintains chromosomal stability as errors in this process contribute to chromosomal instability (CIN), which has been observed in many diseases including cancer. Epigenetic regulation of kinetochore proteins such as Cs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::711f71955e7c7c00906724a91831c474
Autor:
Eisenstatt, Jessica R., Ohkuni, Kentaro, Au, Wei-Chun, Preston, Olivia, Gliford, Loran, Suva, Evelyn, Costanzo, Michael, Boone, Charles, Basrai, Munira A.
Supporting figures S1-S10 are available as JPG files. Supporting Table S1 is an Excel file that describes mutations that suppress the psh1Δ GALCSE4 SDL, the gene systematic name, the gene name, the functional category, growth and colony scores, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b819078f75cc2a2ff18584d7e7cdbd
Autor:
Kerry Bloom, Prashant K. Mishra, Robert A. Sclafani, Peter H. Thorpe, Henry Wood, Lars Boeckmann, Jessica R. Eisenstatt, Munira A. Basrai, John Stanton, Michael Weinreich, Wei-Chun Au
Publikováno v:
Molecular Biology of the Cell
Faithful chromosome segregation maintains chromosomal stability as errors in this process contribute to chromosomal instability (CIN), which has been observed in many diseases including cancer. Epigenetic regulation of kinetochore proteins such as Cs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0629927706f41a331ebc54eaf0f14dd7
http://europepmc.org/articles/PMC8693968
http://europepmc.org/articles/PMC8693968