The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity.

Autor: Cavalli G; Department of Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy., Tengesdal IW; Department of Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA., Gresnigt M; Department of Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany., Nemkov T; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, CO 80045, USA., Arts RJW; Department of Medicine, Radboud University Medical Center, Nijmegen, the Netherlands., Domínguez-Andrés J; Department of Medicine, Radboud University Medical Center, Nijmegen, the Netherlands., Molteni R; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Stefanoni D; Vita-Salute San Raffaele University, Milan, Italy., Cantoni E; Vita-Salute San Raffaele University, Milan, Italy., Cassina L; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Giugliano S; Laboratory of Mucosal Immunology and Microbiota, Humanitas Clinical and Research Center - IRCCS, via Manzoni 56, 20089 Rozzano (MI), Italy., Schraa K; Department of Medicine, Radboud University Medical Center, Nijmegen, the Netherlands., Mills TS; Division of Hematology, Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA., Pietras EM; Division of Hematology, Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA., Eisenmensser EZ; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, CO 80045, USA., Dagna L; Vita-Salute San Raffaele University, Milan, Italy; Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milan, Italy., Boletta A; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy., D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, CO 80045, USA., Joosten LAB; Department of Medicine, Radboud University Medical Center, Nijmegen, the Netherlands., Netea MG; Department of Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Immunology and Metabolism, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany., Dinarello CA; Department of Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA. Electronic address: cdinare333@aol.com.

Publikováno v: Cell reports [Cell Rep] 2021 Apr 06; Vol. 35 (1), pp. 108955.