Výsledky vyhledávání - "Eisaku Kobayashi"

Inhibitory effects of N,N′-diphenyl-p-phenylenediamine on the early stage of the enhanced hepatocarcinogenesis caused by coadministration of ethionine and a choline-deficient L-amino acid-defined diet in rats

Autor: Dai Nakae, Yasushi Mizumoto, Nobuaki Andoh, Masahiro Tsutsumi, Hiromichi Kitada, Yoichi Konishi, Takehiro Endoh, Toshifumi Tsujiuchi, Eisaku Kobayashi, Ayumi Denda

Publikováno v: Experimental and Toxicologic Pathology. 48:275-282

Summary Effects of N,N′ -diphenyl-p-phenylenediamine (DPPD), an antioxidant, on liver carcinogenesis caused by a choline-deficient L-amino acid-defined (CDAA) diet containing ethionine were studied in Fischer 344 rats. Male animals, 6 weeks old, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b726f391779d7168671822915fa7ab3
https://doi.org/10.1016/s0940-2993(96)80019-4

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Disturbance of the Cell Cycle with Colchicine Enhances the Growth Advantage of Diethylnitrosamine-initiated Hepatocytes in Rats

Autor: Masahiro Tsutsumi, Toshio Mori, Takehiro Endoh, Toshifumi Tsujiuchi, Kiyohiko Hasegawa, Kunihiko Kobitsu, Hiromichi Kitada, Yoichi Konishi, Eisaku Kobayashi, Toshimitu Majima, Eijiro Okajima, Kazuo Ohashi

Publikováno v: Japanese Journal of Cancer Research : Gann

The effect of cell cycle disturbance due to colchicine on the induction of enzyme-altered foci during liver regeneration in rats was studied. For initiation, diethylnitrosamine (DEN) at a dose of 10 mg/kg was injected intraperitoneally and partial he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada6232aa0d64376220348cd52263b31
https://doi.org/10.1111/j.1349-7006.1996.tb00192.x

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Prevention by Methionine of Enhancement of Hepatocarcinogenesis by Coadministration of a Choline-deficient L-Amino Acid-defined Diet and Ethionine in Rats

Autor: Toshifumi Tsujiuchi, Yasushi Mizumoto, Tomokazu Fukuda, Eisaku Kobayashi, Akira Kido, Hiromichi Kitada, Dai Nakae, Nobuaki Andoh, Masahiro Tsutsumi, Ayumi Denda, Kazuo Ohashi, Yoichi Konishi

Publikováno v: Japanese Journal of Cancer Research : Gann

The effects of methionine on hepatocarcinogenesis induced by coadministration of a choline-deficient L-amino acid-defined (CDAA) diet and ethionine were examined. F344 male rats were divided into 4 experimental groups. Groups 1 and 2 received the CDA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ae640d821005fe07792ef9d91b5d48
https://doi.org/10.1111/j.1349-7006.1995.tb03306.x

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Improved genomic/nuclear DNA extraction for 8-hydroxydeoxyguanosine analysis of small amounts of rat liver tissue

Autor: Yoichi Konishi, Eisaku Kobayashi, Osamu Noguchi, Yasushi Mizumoto, Dai Nakae

Publikováno v: Cancer Letters. 97:233-239

Using two different commercially available extraction kits, genomic/nuclear DNA could be recovered from rat liver samples as small as 10 mg. Background 8-hydroxydeoxyguanosine levels in such DNA were low and stable at 0.26-0.30 +/- 0.01-0.03/10(5) gu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::748523ef1975620bf574487cc231e6bf
https://doi.org/10.1016/0304-3835(95)03980-b

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Comparative Changes in the Liver of Female Fischer-344 Rats after Short-Term Feeding of a Semipurified or a Semisynthetic L-Amino Acid-Defined Choline-Deficient Diet

Autor: Benito Lombardi, Ayumi Denda, Yasushi Mizumoto, Yoichi Konishi, Nobuaki Andoh, Kohsuke Horiguchi, Eisaku Kobayashi, Kazutoshi Tamura, Toshifumi Tsujiuchi, Takehiro Endoh, Dai Nakae

Publikováno v: Toxicologic Pathology. 23:583-590

Groups of female Fischer-344 rats were fed a semipurified choline-deficient (CD) diet, or a semisynthetic L-amino acid-defined choline-deficient (CDAA) diet, for up to 12 wk and effects of the 2 diets on the liver were compared. Steatosis was diffuse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30eac9dd1294e7fbb27b3866e0ec4a8d
https://doi.org/10.1177/019262339502300504

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Initiation of hepatocarcinogenesis by endogenously formed N-nitrosobis(2-hydroxypropyl)amine, N-nitrosodiethanolamine and N-nitroso-2,6-dimethylmorpholine in rats

Autor: Eijiro Okajima, Takehiro Endoh, Masahiro Tsutsumi, Yukio Mori, Eisaku Kobayashi, Osamu Noguchi, Yoichi Konishi, Ayumi Denda, Kazuhiko Yamamoto

Publikováno v: Carcinogenesis. 16:2633-2636

Initiation activities of endogenously formed N-nitrosobis(2-hydroxypropyl)amine (NBHPA), N-nitrosodiethanolamine (NDELA) and N-nitroso-2,6-dimethylmorpholine (NDMM) were investigated in a modified short-term assay for rat hepatocarcinogenesis. Male W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095e87e396b9f66a163e0221d7f54642
https://doi.org/10.1093/carcin/16.11.2633

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Expression ofcriptoin Human Pancreatic Tumors

Autor: Osamu Ishikawa, Kazuo Ohashi, Shunji Okita, Kohsuke Horiguchi, Hiromichi Kitada, Eisaku Kobayashi, Osamu Noguchi, Wataru Yasui, Yoichi Konishi, Toshifumi Tsujiuchi, Masahiro Tsutsumi, Eiichi Tahara, Azusa Naito

Publikováno v: Japanese Journal of Cancer Research : Gann

The expression of cripto gene product was examined immunohistochemically in 45 surgically resected pancreatic tumors, including 32 invasive ductal carcinomas, 4 intraductal papillary adenocarcinomas, 4 intraductal papillary adenomas, 2 mucinous cysta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ae89adfdf34a9087029d8b05144f41
https://doi.org/10.1111/j.1349-7006.1994.tb02069.x

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INDUCTION OF COLON ADENOCARCINOMAS BY 1,2-DIMETHYLHYDRAZINE IN (C3H*MSM) F1 MICE

Autor: Toshifumi Tsujiuchi, Kohsuke Horiguchi, Kazuo Moriwaki, Shunji Okita, Yoichi Konishi, Masahiro Tsutsumi, Nobumoto Miyashita, Eisaku Kobayashi, Osamu Noguchi

Publikováno v: Journal of Toxicologic Pathology. 7:461-464

The possibility of producing colon tumors by administration of 1, 2-dimethylhydrazine (DMH) to (C3H×MSM) F1 hybrids of inbred and wild strains mice, was investigated in an attempt to establish an experimental model for detection of DNA polymorphism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1af3ea36bd721c4fc1ac4dd7f3a16f3d
https://doi.org/10.1293/tox.7.461

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Study on the Castability of Co-Cr Alloy for Cast Plates. Part 3. Effects of Alloy Fusion Temperature and the Heating Temperature of the Cast Ring

Autor: Yoshinori SATOH, Tetsuo OHYAMA, Eiichi NAGAI, Masamichi MATSUZU, Hitoshi TOYOMA, Masaaki OHWA, Eisaku KOBAYASHI, Hitoshi SAKURAI, Katsuzo OHKI, Minoru NISHIYAMA, Yoshie SHIINA, Kazutaka MAEDA

Publikováno v: The Journal of Nihon University School of Dentistry. 35:49-56

Co-Cr alloy is used more frequently than Ni-Cr alloy as a non-precious alloy for cast plates in Japan. However, since the melting temperature of Co-Cr alloy is very high, about 1300 degrees C, and since it oxidizes easily, a vacuum-pressure casting m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567f2996d9cfd9b4b42bb3f7925fffdf
https://doi.org/10.2334/josnusd1959.35.49

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