Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Eirunn Knudsen"'
Publikováno v:
International Journal of Hematology. 100:111-118
Nuclear factor-kappa B (NF-κB) is a multipotent transcription factor that plays a pivotal role in immune reactions, inflammation, and possibly hematopoiesis as well. Mobilization of neutrophilic granulocytes during inflammation is a highly regulated
Autor:
Per Ole Iversen, Therese Seierstad, Gunnar Nicolaysen, Arne Bøyum, Eirunn Knudsen, Haakon B. Benestad
Publikováno v:
European Journal of Haematology. 87:302-311
Objectives: Whether G-CSF enhances the maturation of neutrophilic granulocytes or just accelerates the mobilization of mature and maturing granulocytes from bone marrow to blood, or both, is not clear. Using an in vivo culture system where such mobil
Autor:
Per Kristian Opstad, Arne Bøyum, Helge Tolleshaug, Oddvar Myhre, Magnar Bjørås, Christine Gran Neurauter, Haakon B. Benestad, Vivi-Ann Tennfjord, Eirunn Knudsen, Knut Kristian Skrede
Publikováno v:
Toxins
Toxins; Volume 2; Issue 1; Pages: 95-115
Toxins; Volume 2; Issue 1; Pages: 95-115
INFLAMMATORY MEDIATORS TRIGGER POLYMORPHONUCLEAR NEUTROPHILS (PMN) TO PRODUCE REACTIVE OXYGEN SPECIES (ROS: O(2) (-), H(2)O(2), ∙OH). Mediated by myeloperoxidase in PMN, HOCl is formed, detectable in a chemiluminescence (CL) assay. We have shown th
Publikováno v:
Cancer Immunology, Immunotherapy. 59:575-586
The aims of this study are to examine the effect of sphingosine 1-phosphate (S1P) on IL-2-activated natural killer (NK) cell lysis of K562 tumor cells and immature dendritic cells (iDCs), and to investigate the mechanisms involved in S1P activity. Ou
Publikováno v:
Scopus-Elsevier
The fate of polymorphonuclear neutrophilic granulocytes (PMN) after their mobilization from the bone marrow of healthy individuals is not clearly understood. It has been suggested that there is a continuous utilization of these cells in widespread, s
Autor:
Bassam B. Damaj, Kristin L. Sand, Yassin Al‐Falahi, Azzam A. Maghazachi, Johannes Rolin, Eirunn Knudsen
Publikováno v:
Journal of Cellular and Molecular Medicine. 13:2693-2703
Natural killer (NK) cells are antitumour/anti‐viral effectors and play important roles in shaping the immune system, but their role in neurodegenerative diseases is not clear. Here, we investigated the fate of these cells in two neurodegenerative d
Publikováno v:
European Journal of Haematology. 73:109-122
Objective The exact fate of polymorphonuclear neutrophilic granulocytes (PMN; neutrophils) after their mobilization from the bone marrow is not known. It is believed that they, after a relatively short lifespan (1-3 d), become apoptotic and phagocyto
Publikováno v:
Biochemical and Biophysical Research Communications. 320:810-815
Natural killer (NK) cells perform multiple biological functions including tumor cell lysis and eradicating virally infected cells. Here, we report for the first time that D-galactosyl-beta1-1' sphingosine and D-glucosyl-beta1- 1' sphingosine damage h
Autor:
Eirunn, Knudsen, Per Ole, Iversen, Arne, Bøyum, Therese, Seierstad, Gunnar, Nicolaysen, Haakon B, Benestad
Publikováno v:
European journal of haematology. 87(4)
Whether G-CSF enhances the maturation of neutrophilic granulocytes or just accelerates the mobilization of mature and maturing granulocytes from bone marrow to blood, or both, is not clear. Using an in vivo culture system where such mobilization cann
Autor:
Håvard Attramadal, Bushra Ishaq, Eirunn Knudsen, Vladimir N. Martinov, Gabor Czibik, Guro Valen, Jørgen Gravning
Publikováno v:
Life sciences. 88(11-12)
Gene therapy of a peripheral organ to protect the heart is clinically attractive. The transcription factor hypoxia-inducible factor 1 alpha (HIF-1α) transactivates cardioprotective genes. We investigated if remote delivery of DNA encoding for HIF-1