Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Eirini Sevdali"'
Autor:
Ioannis Kakkas, Gerasimina Tsinti, Fani Kalala, Evangelia Farmaki, Alexandra Kourakli, Androniki Kapousouzi, Maria Dimou, Vassiliki Kalaitzidou, Eirini Sevdali, Athanasia-Marina Peristeri, Georgia Tsiouma, Peristera Patiou, Eleni Papadimitriou, Theodoros P. Vassilakopoulos, Panayiotis Panayiotidis, Anna Kioumi, Argiris Symeonidis, Matthaios Speletas
Publikováno v:
Medicina, Vol 57, Iss 8, p 827 (2021)
Background and objectives: Monoallelic (heterozygous) or biallelic (homozygous or compound heterozygous) TACI mutations have been reported as the most common genetic defects in patients with common variable immunodeficiency (CVID), which is the most
Externí odkaz:
https://doaj.org/article/6613eee1a5c341ba8d743ea140ff4d35
Autor:
Eirini Sevdali, Eleni Katsantoni, Cristian R. Smulski, Maria Moschovi, Maria Palassopoulou, Eleni-Nefeli Kolokotsa, Nikoletta Argentou, Nikolaos Giannakoulas, Maria Adamaki, Georgios Vassilopoulos, Sophia Polychronopoulou, Anastasios E. Germenis, Hermann Eibel, Matthaios Speletas
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
BAFF, APRIL and their receptors regulate the survival, maturation and homeostasis of mature B-cells. Despite the lack of a functional role of BAFF/APRIL system during normal early B-cell development, previous studies indicated a contribution of these
Externí odkaz:
https://doaj.org/article/e2086a125c6c4fdba9c4c6355537ebb0
Autor:
Heiko Sic, Matthaios Speletas, Vanessa Cornacchione, Maximillian Seidl, Martin Beibel, Bolan Linghu, Fan Yang, Eirini Sevdali, Anastasios E. Germenis, Edward J. Oakeley, Eric Vangrevelinghe, Andreas W. Sailer, Elisabetta Traggiai, Hermann Gram, Hermann Eibel
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Heterozygous mutations in the cytotoxic T lymphocyte antigen-4 (CTLA-4) are associated with lymphadenopathy, autoimmunity, immune dysregulation, and hypogammaglobulinemia in about 70% of the carriers. So far, the incomplete penetrance of CTLA-4 haplo
Externí odkaz:
https://doaj.org/article/f19ae274f20a4660b1e458e9f4e08a77
Autor:
Eirini Sevdali, Elena Tsitsami, Maria Tsinti, Evangelia Farmaki, Efimia Papadopoulou-Alataki, Anastasios E. Germenis, Matthaios Speletas
Publikováno v:
Journal of Immunology Research, Vol 2017 (2017)
Sialic acid acetylesterase (SIAE) deficiency was suggested to lower the levels of ligands for sialic acid-binding immunoglobulin-like receptors, decreasing the threshold for B-cell activation. In humans, studies of rare heterozygous loss-of-function
Externí odkaz:
https://doaj.org/article/04d5ea145ca74e94ae822dbacd4b3f85
Autor:
Matthaios Speletas, Antonios Gounaris, Eirini Sevdali, Maria Kompoti, Katerina Konstantinidi, Rozeta Sokou, Elena Tsitsami, Anastasios E. Germenis
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
The objective of this study was to assess the frequency of MBL2 genotypes and their associations with MBL levels and various morbidities of a neonatal intensive care unit (NICU). One hundred and thirty-four (134) NICU (83 term and 51 preterm) and 150
Externí odkaz:
https://doaj.org/article/c310ff8633394808b5f3dba18e129ece
Autor:
Violeta Block, Eirini Sevdali, Mike Recher, Hassan Abolhassani, Lennart Hammarstrom, Cristian R. Smulski, Manuela Baronio, Alessandro Plebani, Michele Proietti, Matthaios Speletas, Klaus Warnatz, Reinhard E. Voll, Vassilios Lougaris, Pascal Schneider, Hermann Eibel
Publikováno v:
Journal of clinical immunology, vol. 43, no. 2, pp. 391-405
Purpose Binding of the B cell activating factor (BAFF) to its receptor (BAFFR) activates in mature B cells many essential pro-survival functions. Null mutations in the BAFFR gene result in complete BAFFR deficiency and cause a block in B cell develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc6a94e0c36208809609b4b2517259fe
https://serval.unil.ch/resource/serval:BIB_2DE9DC2406E5.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_2DE9DC2406E5.P001/REF.pdf
Publikováno v:
Current Opinion in Immunology. 71:103-110
The BAFF-receptor (BAFFR) is a member of the TNF-receptor family. It is expressed only by B cells and binds BAFF as single ligand, which activates key signaling pathways regulating essential cellular functions, including survival, protein synthesis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577502a1069169c2ebbb4021b4d67802
https://doi.org/10.1016/j.coi.2021.06.008
https://doi.org/10.1016/j.coi.2021.06.008
Autor:
George N. Dalekos, Matthaios Speletas, Eirini Sevdali, Aggeliki Lyberopoulou, Pinelopi Arvaniti, Maria Ioannou, Kalliopi Zachou, George K. Koukoulis, Yves Renaudineau
Publikováno v:
Liver International
Liver International, 2022, ⟨10.1111/liv.15176⟩
Liver International, 2022, ⟨10.1111/liv.15176⟩
ObjectiveAIH is a chronic liver disease of unknown aetiology with favourable response to immunosuppression. Little is known about the impact of methylation modifications on disease pathogenesis.Design10 patients with AIH at diagnosis (time-point 1; t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e556d9b033feedf70198f4ca81e4372
https://doi.org/10.1101/2021.07.01.21259836
https://doi.org/10.1101/2021.07.01.21259836
Autor:
Eirini Sevdali, Violeta Block, Marie Lataretu, Huiying Li, Cristian R. Smulski, Jana-Susann Briem, Yannic Heitz, Beate Fischer, Neftali-Jose Ramirez, Bodo Grimbacher, Hans-Martin Jäck, Reinhard E. Voll, Martin Hölzer, Pascal Schneider, Hermann Eibel
Publikováno v:
Cell reports, vol. 39, no. 13, pp. 111019
Binding of BAFF to BAFFR activates in mature B cells PI3K/AKT signaling regulating protein synthesis, metabolic fitness, and survival. In humans, naive and memory B cells express the same levels of BAFFR, but only memory B cells seem to survive witho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c89a50854c4165b9b92eb2c12a699f6d
https://doi.org/10.1016/j.celrep.2022.111019
https://doi.org/10.1016/j.celrep.2022.111019
Autor:
Cristian R. Smulski, Luyao Zhang, Malte Burek, Ariadna Teixidó Rubio, Jana-Susann Briem, Mauricio P. Sica, Eirini Sevdali, Michele Vigolo, Laure Willen, Patricia Odermatt, Duygu Istanbullu, Stephanie Herr, Marco Cavallari, Henry Hess, Marta Rizzi, Hermann Eibel, Pascal Schneider
Publikováno v:
Cell reports, vol. 38, no. 13, pp. 110583
In mature B cells, TACI controls class-switch recombination and differentiation into plasma cells during T cell-independent antibody responses. TACI binds the ligands BAFF and APRIL. Approximately 10% of patients with common variable immunodeficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2645ba5913a8d25cf852dcd7f715418
https://pubmed.ncbi.nlm.nih.gov/35354034
https://pubmed.ncbi.nlm.nih.gov/35354034