Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Eirini Pectasides"'
Autor:
Hui Zheng, Eirini Pectasides, Mohamed Uduman, Charles S Fuchs, James M Cleary, Adam J Bass, Jérémy Augustin, Leonie K de Klerk, Anuj K Patel, Sarah Derks, Nihal Raman, Fahire G Akarca, Nadine J McCleary, Douglas A Rubinson, Jeffrey W Clark, Bridget Fitzpatrick, Lauren K Brais, Megan E Cavanaugh, Amanda J Rode, Melissa G Jean, Patrick H Lizotte, Matthew J Nazzaro, Peter C Enzinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/88b5dffda1124385a9d172a7073bce20
Autor:
Jin Zhou, Zhong Wu, Gabrielle Wong, Eirini Pectasides, Ankur Nagaraja, Matthew Stachler, Haikuo Zhang, Ting Chen, Haisheng Zhang, Jie Bin Liu, Xinsen Xu, Ewa Sicinska, Francisco Sanchez-Vega, Anil K. Rustgi, J. Alan Diehl, Kwok-Kin Wong, Adam J. Bass
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Oesophageal squamous cell carcinoma often develop resistance to EGFR tyrosine kinase inhibitors. Here, the authors demonstrate that inhibition of cell cycle regulators CDK4/6 or MAPK blockade enhances the efficacy of EGFR inhibitors for these tumours
Externí odkaz:
https://doaj.org/article/282f92eea86c444d9bab4d8683fb7b94
Autor:
Elena Fountzilas, George Pentheroudakis, Kyriaki Manousou, Genovefa Polychronidou, Eleni Vrettou, Christos Poulios, Georgia Raptou, Eirini Pectasides, Georgia Karayannopoulou, Sofia Chrisafi, Pavlos Papakostas, Thomas Makatsoris, Ioannis Varthalitis, Amanda Psyrri, Mattheos Bobos, Christos Christodoulou, Christos Papadimitriou
Publikováno v:
ESMO Open, Vol 4, Iss 2 (2019)
Background The clinical relevance of mismatch repair (MMR) status in patients with nonmetastatic cancer across tumour types remains unclear. Our goal was to investigate the prognostic role of MMR deficiency in patients with stage I-III colorectal and
Externí odkaz:
https://doaj.org/article/75468790ebb3419a9006d286fb10c6a7
Autor:
Eirini Pectasides, Theodoros Rampias, Clarence Sasaki, Christos Perisanidis, Vassilis Kouloulias, Barbara Burtness, Thomas Zaramboukas, David Rimm, George Fountzilas, Amanda Psyrri
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94273 (2014)
BACKGROUND:Elucidating the molecular phenotype of cancers with high metastatic potential will facilitate the development of novel therapeutic approaches to the disease. Gene expression profiles link epithelial to mesenchymal transition (EMT) phenotyp
Externí odkaz:
https://doaj.org/article/c3fe29260288480885a792a6722f0c09
Autor:
Petr Pancoska, John M Kirkwood, Spyros Bouros, Maria Spyropoulou-Vlachou, Eirini Pectasides, Dimosthenis Tsoutsos, Aristidis Polyzos, Christos Markopoulos, Petros Panagiotou, Ourania Castana, Dimitrios Bafaloukos, George Fountzilas, Helen Gogas
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86375 (2014)
Adjuvant therapy of stage IIB/III melanoma with interferon reduces relapse and mortality by up to 33% but is accompanied by toxicity-related complications. Polymorphisms of the CTLA-4 gene associated with autoimmune diseases could help in identifying
Externí odkaz:
https://doaj.org/article/d34cf737704242488debe7b0f518023f
Autor:
Yong Sang Hong, Jihun Kim, Eirini Pectasides, Cameron Fox, Seung-Woo Hong, Qiuping Ma, Gabrielle S Wong, Shouyong Peng, Matthew D Stachler, Aaron R Thorner, Paul Van Hummelen, Adam J Bass
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109440 (2014)
ERBB2-directed therapy is now a routine component of therapy for ERBB2-amplified metastatic gastroesophageal adenocarcinomas. However, there is little knowledge of the mechanisms by which these tumors develop acquired resistance to ERBB2 inhibition.
Externí odkaz:
https://doaj.org/article/a1151361100241e2881c2ca0f3850f79
Autor:
Daniel V. Catenacci, Adam J. Bass, Jeeyun Lee, Viktor Adalsteinsson, Yu Imamura, Jon Davison, Denisse Rotem, Greg Gydush, Sarah Reed, Justin Rhoades, Samuel S. Freeman, Gavin Ha, Andres Gelrud, Uzma Siddiqui, Kyle Hogarth, Paul Chang, Kiran Turaga, Kevin Roggin, Mitchell C. Posner, Yuan Ji, Haley A. Coleman, Bruce M. Wollison, Matthew D. Ducar, Aaron R. Thorner, Andrew Dunford, David J. Oh, Agoston T. Agoston, Rick Lanman, Hideo Baba, Masayuki Watanabe, Lea O'Keefe, Katie S. Nason, Byung-Hoon Min, Min-Gew Choi, Kyoung-Mee Kim, Rebecca J. Nagy, John Hart, Shu-Yuan Xiao, Namrata Setia, Christopher Weber, Carrie Fitzpatrick, Rajani Kanteti, Melissa Maranto, Samantha Lomnicki, Emily O'Day, Kenisha Allen, Manish R. Sharma, Blase Polite, Hedy Kindler, Heewon Kwak, Lindsay Alpert, Mirazul Islam, Steven Maron, Yang Liu, Sarah Derks, Matthew D. Stachler, Eirini Pectasides
Supplementary Fig. 1: Mutation rate and ploidy for each individual patient's primary and metastatic sample (cohort 1);Supplementary Fig. 2: Validation of genomic heterogeneity within primary tumor and between primary tumor and lymph node (LN) metasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983d30a92fc5950bf814c139a986a833
https://doi.org/10.1158/2159-8290.22534244.v1
https://doi.org/10.1158/2159-8290.22534244.v1
Autor:
Amanda Psyrri, Paul Weinberger, Panteleimon Kountourakis, Clarence Sasaki, Eirini Pectasides, Eleni Boutati, Theodore Rampias
We sought to determine the role of human papillomavirus (HPV) E6 and E7 oncogenes in nuclear β-catenin accumulation, a hallmark of activated canonical Wnt signaling pathway. We used HPV16-positive oropharyngeal cancer cell lines 147T and 090, HPV-ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c44106a76ab1038469da56e13abb9ca
https://doi.org/10.1158/1541-7786.c.6542121
https://doi.org/10.1158/1541-7786.c.6542121
Autor:
Daniel V. Catenacci, Adam J. Bass, Jeeyun Lee, Viktor Adalsteinsson, Yu Imamura, Jon Davison, Denisse Rotem, Greg Gydush, Sarah Reed, Justin Rhoades, Samuel S. Freeman, Gavin Ha, Andres Gelrud, Uzma Siddiqui, Kyle Hogarth, Paul Chang, Kiran Turaga, Kevin Roggin, Mitchell C. Posner, Yuan Ji, Haley A. Coleman, Bruce M. Wollison, Matthew D. Ducar, Aaron R. Thorner, Andrew Dunford, David J. Oh, Agoston T. Agoston, Rick Lanman, Hideo Baba, Masayuki Watanabe, Lea O'Keefe, Katie S. Nason, Byung-Hoon Min, Min-Gew Choi, Kyoung-Mee Kim, Rebecca J. Nagy, John Hart, Shu-Yuan Xiao, Namrata Setia, Christopher Weber, Carrie Fitzpatrick, Rajani Kanteti, Melissa Maranto, Samantha Lomnicki, Emily O'Day, Kenisha Allen, Manish R. Sharma, Blase Polite, Hedy Kindler, Heewon Kwak, Lindsay Alpert, Mirazul Islam, Steven Maron, Yang Liu, Sarah Derks, Matthew D. Stachler, Eirini Pectasides
Gastroesophageal adenocarcinoma (GEA) is a lethal disease where targeted therapies, even when guided by genomic biomarkers, have had limited efficacy. A potential reason for the failure of such therapies is that genomic profiling results could common
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b6ea79102b00169cfaf145b8d3b0505
https://doi.org/10.1158/2159-8290.c.6547418.v1
https://doi.org/10.1158/2159-8290.c.6547418.v1
Autor:
Amanda Psyrri, Paul Weinberger, Panteleimon Kountourakis, Clarence Sasaki, Eirini Pectasides, Eleni Boutati, Theodore Rampias
Supplementary Data from Activation of Wnt Signaling Pathway by Human Papillomavirus E6 and E7 Oncogenes in HPV16-Positive Oropharyngeal Squamous Carcinoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e8e35a5c485a316b7cfb5ba451f2f6
https://doi.org/10.1158/1541-7786.22518804
https://doi.org/10.1158/1541-7786.22518804