Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eirini Giannoudaki"'
Autor:
Georgina C. Wilkins, Jenny Gilmour, Eirini Giannoudaki, John A. Kirby, Neil S. Sheerin, Simi Ali
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 11192 (2023)
Sphingosine 1-phosphate (S1P) and S1P receptors (S1PR) regulate many cellular processes, including lymphocyte migration and endothelial barrier function. As neutrophils are major mediators of inflammation, their transendothelial migration may be the
Externí odkaz:
https://doaj.org/article/ecc87b7f53a24a51aff72115c9bea351
Autor:
Eirini Giannoudaki, Yasmina E. Hernandez-Santana, Kelly Mulfaul, Sarah L. Doyle, Emily Hams, Padraic G. Fallon, Arimin Mat, Donal O’Shea, Manfred Kopf, Andrew E. Hogan, Patrick T. Walsh
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
IL-36α,β and ɣ are IL-1-related cytokines promoting inflammation in the skin and intestine. Here the authors show they are elevated in individuals with obesity, and that mice lacking the IL-36 receptor antagonist are more resistant to diet-induced
Externí odkaz:
https://doaj.org/article/bc1452cbf30c4db3ab7be1abbb926ebf
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
T cell subsets are considered central orchestrators of inflammation and homeostasis in the intestine and are established targets for the treatment of inflammatory bowel disease. While approaches aimed at the neutralization of T cell effector cytokine
Externí odkaz:
https://doaj.org/article/503281bc3ded4424a8dde0c5e201bd17
Autor:
Gemma Leon, Yasmina E. Hernandez Santana, Naoise Irwin, Eirini Giannoudaki, Sadhbh O'Neill, Ilona Csizmadia, Martina Gogarty, Tae J. Lee, Darren Ruane, Aideen Long, Padraic G. Fallon, Seamus Hussey, Patrick T. Walsh
Publikováno v:
Mucosal Immunology. 15:491-503
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3107460e2544667e1b0821f6ee027d24
https://doi.org/10.1038/s41385-022-00488-w
https://doi.org/10.1038/s41385-022-00488-w
Autor:
Rachel M. Horan, Shane E. Russell, Padraic G. Fallon, Patrick T. Walsh, Roger S Preston, Cecilia Garlanda, Hazel Lawler, Anna M. Stefanska, Gemma Leon, Eirini Giannoudaki, Yasmina E Hernandez Santana, Cheryl M. Sweeney, Alberto Mantovani, Najma Hassan
Publikováno v:
The Journal of Immunology. 207:651-660
SIGIRR has been described as a negative regulator of several IL-1R/TLR family members and has been implicated in several inflammatory disease conditions. However, it is unknown whether it can suppress IL-36 family cytokines, which are members of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c468eb8e9945cbacdc034b493ee47d
https://doi.org/10.4049/jimmunol.2100237
https://doi.org/10.4049/jimmunol.2100237
Autor:
Eirini Giannoudaki, Anna M. Stefanska, Hazel Lawler, Gemma Leon, Yasmina E. Hernandez Santana, Najma Hassan, Shane E. Russell, Rachel Horan, Cheryl Sweeney, Roger S. Preston, Alberto Mantovani, Cecilia Garlanda, Padraic G. Fallon, Patrick T. Walsh
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 207(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d2ccb73dc10ce59342d34b523c80b9
https://pubmed.ncbi.nlm.nih.gov/34253575
https://pubmed.ncbi.nlm.nih.gov/34253575
Autor:
Arimin Mat, Manfred Kopf, Sarah L. Doyle, Andrew E. Hogan, Kelly Mulfaul, Yasmina E. Hernandez-Santana, Donal O'Shea, Eirini Giannoudaki, Emily Hams, Padraic G. Fallon, Patrick T. Walsh
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications, 10 (1)
Nature Communications
Nature Communications, 10 (1)
Nature Communications
Members of the interleukin-1 (IL-1) family are important mediators of obesity and metabolic disease and have been described to often play opposing roles. Here we report that the interleukin-36 (IL-36) subfamily can play a protective role against the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf9e8d042ad9bb02889712050484449
https://doaj.org/article/bc1452cbf30c4db3ab7be1abbb926ebf
https://doaj.org/article/bc1452cbf30c4db3ab7be1abbb926ebf
Autor:
Gemma, Leon, Yasmina E, Hernandez Santana, Naoise, Irwin, Eirini, Giannoudaki, Sadhbh, O'Neill, Ilona, Csizmadia, Martina, Gogarty, Tae J, Lee, Darren, Ruane, Aideen, Long, Padraic G, Fallon, Seamus, Hussey, Patrick T, Walsh
Publikováno v:
Mucosal immunology. 15(3)
IL-36 cytokines are emerging as potent orchestrators of intestinal inflammation and are being implicated in the pathogenesis of inflammatory bowel diseases (IBD). However, the mechanisms through which these cytokines mediate these effects remain to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ab3fdc4b0e3d3e7bef115e4edb1d506
https://pubmed.ncbi.nlm.nih.gov/35177818
https://pubmed.ncbi.nlm.nih.gov/35177818
Publikováno v:
Cell Health and Cytoskeleton. :63
Correspondence: Simi Ali Applied Immunobiology and Transplantation Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK Tel +44 (0)191 222 7158 Email simi.ali@newcastle.ac.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::009e594ad8a84c62ba013012252b86c8
https://doi.org/10.2147/chc.s34014
https://doi.org/10.2147/chc.s34014