Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer.

Autor: Einstein JM; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA., Perelis M; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA., Chaim IA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA., Meena JK; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Nussbacher JK; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA., Tankka AT; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA., Yee BA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA., Li H; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Madrigal AA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA., Neill NJ; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Shankar A; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA., Tyagi S; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Westbrook TF; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, TX 77030, USA., Yeo GW; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA. Electronic address: geneyeo@ucsd.edu.

Publikováno v: Molecular cell [Mol Cell] 2021 Aug 05; Vol. 81 (15), pp. 3048-3064.e9. Date of Electronic Publication: 2021 Jul 02.

Protein-RNA interaction dynamics reveal key regulators of oncogenic KRAS-driven cancers.

Autor: Ban, Ka-Yun¹ (AUTHOR), Na, Yong-woo² (AUTHOR), Song, Juhan¹ (AUTHOR), Kim, Jong-Seo² (AUTHOR), Kim, Jimi^1,3 (AUTHOR) zimic@gachon.ac.kr

Publikováno v: Scientific Reports. 11/7/2024, Vol. 14 Issue 1, p1-10. 10p.

N6-Methyladenosine methylation modification in breast cancer: current insights.

Autor: Zhang, Guangwen¹ (AUTHOR) workzgw@163.com, Cheng, Chen² (AUTHOR), Wang, Xinle¹ (AUTHOR), Wang, Shiming³ (AUTHOR) wangshiming@sxmu.edu.cn

Publikováno v: Journal of Translational Medicine. 10/28/2024, Vol. 22 Issue 1, p1-16. 16p.

Pooled CRISPR screens with imaging on microraft arrays reveals stress granule-regulatory factors.

Autor: Wheeler EC; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine and UCSD Stem Cell Program, University of California San Diego, La Jolla, CA, USA., Vu AQ; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine and UCSD Stem Cell Program, University of California San Diego, La Jolla, CA, USA., Einstein JM; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine and UCSD Stem Cell Program, University of California San Diego, La Jolla, CA, USA., DiSalvo M; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill and Raleigh, NC, USA., Ahmed N; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine and UCSD Stem Cell Program, University of California San Diego, La Jolla, CA, USA., Van Nostrand EL; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine and UCSD Stem Cell Program, University of California San Diego, La Jolla, CA, USA., Shishkin AA; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine and UCSD Stem Cell Program, University of California San Diego, La Jolla, CA, USA.; Eclipse BioInnovations, San Diego, CA, USA., Jin W; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine and UCSD Stem Cell Program, University of California San Diego, La Jolla, CA, USA., Allbritton NL; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill and Raleigh, NC, USA.; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Bioengineering, University of Washington, Seattle, WA, USA., Yeo GW; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA. geneyeo@ucsd.edu.; Institute for Genomic Medicine and UCSD Stem Cell Program, University of California San Diego, La Jolla, CA, USA. geneyeo@ucsd.edu.

Publikováno v: Nature methods [Nat Methods] 2020 Jun; Vol. 17 (6), pp. 636-642. Date of Electronic Publication: 2020 May 11.

miR-340-3p-modified bone marrow mesenchymal stem cell-derived exosomes inhibit ferroptosis through METTL3-mediated m⁶A modification of HMOX1 to promote recovery of injured rat uterus.

Autor: Xiao, Bang¹ (AUTHOR), Zhu, Yiqing¹ (AUTHOR), Liu, Meng¹ (AUTHOR), Chen, Meiting¹ (AUTHOR), Huang, Chao² (AUTHOR), Xu, Dabing³ (AUTHOR), Wang, Fang¹ (AUTHOR), Sun, Shuhan¹ (AUTHOR), Huang, Jinfeng¹ (AUTHOR) jfhuang027@hotmail.com, Sun, Ningxia³ (AUTHOR) suesunchzh@126.com, Yang, Fu^1,3 (AUTHOR) yangfusq1997@smmu.edu.cn

Publikováno v: Stem Cell Research & Therapy. 7/29/2024, Vol. 15 Issue 1, p1-23. 23p.