Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Einars Loza"'
Autor:
Diana Zelencova-Gopejenko, Aiga Grandane, Einars Loza, Daina Lola, Anda Sipola, Edgars Liepinsh, Pavel Arsenyan, Kristaps Jaudzems
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1723-1729
ε-Trimethyllysine dioxygenase (TMLD) is a non-heme Fe(II) and α-ketoglutarate dependent oxygenase that catalyzes the stereospecific hydroxylation of ε-trimethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c658d0aca97ae321a2e3fd6997debf
https://doi.org/10.1021/acsmedchemlett.2c00261
https://doi.org/10.1021/acsmedchemlett.2c00261
Autor:
Qing Zhang, Charles M. Perou, Huanghe Yang, Yan Peng, Einars Loza, Victor G. Andrianov, Travis S. Ptacek, Jeremy M. Simon, Lianxin Hu, Giada Zurlo, Jin Zhou, Mamoru Takada, Jason W. Locasale, Juan Liu, Laura E. Herring, Cheng Fan, Yang Zhang, Chengheng Liao
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1a196365b69b55815d36998a4ff66f
https://doi.org/10.1158/2159-8290.22535318
https://doi.org/10.1158/2159-8290.22535318
Autor:
Qing Zhang, Charles M. Perou, Huanghe Yang, Yan Peng, Einars Loza, Victor G. Andrianov, Travis S. Ptacek, Jeremy M. Simon, Lianxin Hu, Giada Zurlo, Jin Zhou, Mamoru Takada, Jason W. Locasale, Juan Liu, Laura E. Herring, Cheng Fan, Yang Zhang, Chengheng Liao
Triple-negative breast cancer (TNBC) is an aggressive and highly lethal disease. Because of its heterogeneity and lack of hormone receptors or HER2 expression, targeted therapy is limited. Here, by performing a functional siRNA screening for 2-OG–d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a61a0fd9b7345fe85ece52174cd560c
https://doi.org/10.1158/2159-8290.c.6547829.v1
https://doi.org/10.1158/2159-8290.c.6547829.v1
Autor:
Qing Zhang, Charles M. Perou, Huanghe Yang, Yan Peng, Einars Loza, Victor G. Andrianov, Travis S. Ptacek, Jeremy M. Simon, Lianxin Hu, Giada Zurlo, Jin Zhou, Mamoru Takada, Jason W. Locasale, Juan Liu, Laura E. Herring, Cheng Fan, Yang Zhang, Chengheng Liao
Table S1. List of 65 2-OG dioxygenases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ade5c80f5497c480f31fe643d507fd4
https://doi.org/10.1158/2159-8290.22535315.v1
https://doi.org/10.1158/2159-8290.22535315.v1
Autor:
Y Peng, Jeremy M. Simon, Travis S. Ptacek, Lianxin Hu, Huanghe Yang, Einars Loza, Jin Zhou, Jason W. Locasale, Mamoru Takada, Juan Liu, Chengheng Liao, Yang Zhang, Charles M. Perou, Qing Zhang, Cheng Fan, Giada Zurlo, Victor Andrianov, Laura E. Herring
Publikováno v:
Cancer Discov
Triple-negative breast cancer (TNBC) is an aggressive and highly lethal disease. Because of its heterogeneity and lack of hormone receptors or HER2 expression, targeted therapy is limited. Here, by performing a functional siRNA screening for 2-OG–d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b715d7d76a88341a493858713d1a7d
https://pubmed.ncbi.nlm.nih.gov/32690540
https://pubmed.ncbi.nlm.nih.gov/32690540
Autor:
Kirill Shubin, Douglas L. Huseby, Sha Cao, Martins Ikaunieks, Kavita Yadav, Emilie Racine, Martins Katkevics, Maxime Gualtieri, Diarmaid Hughes, Tatyana Kukosha, Matthieu Sarciaux, Karin Hjort, Marine Serri, Einars Loza, Nadezhda Trufilkina, Victoria Ryabova, Edgars Suna, Lucile Pantel
A structure-activity relationship (SAR) study of NOSO-95179, a nonapeptide from the Odilorhabdin class of antibacterials, was performed by systematic variations of amino acids in positions 2 and 5 of the peptide. A series of non-proteinogenic amino a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc90c42ce5241631d877ea514cb999b5
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-414288
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-414288
Autor:
Juan Liu, Travis S. Ptacek, Huanghe Yang, Einars Loza, Jason W. Locasale, Jeremy M. Simon, Y Peng, Qing Zhang, Jin Zhou, Cheng Fan, Lianxin Hu, Giada Zurlo, Victor Andrianov, Mamoru Takada, Charles M. Perou, Laura E. Herring, Chengheng Liao, Yang Zhang
Publikováno v:
Cancer Research. 81:PD15-10
Triple-negative breast cancer (TNBC), which accounts for 15-20% of breast cancers, causes the highest mortality rate among all breast cancer subtypes. Due to its heterogeneity and lack of estrogen and progesterone receptor or human epidermal growth f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf8a6fb5dba1b1aa0909850f8f4995aa
https://doi.org/10.1158/1538-7445.sabcs20-pd15-10
https://doi.org/10.1158/1538-7445.sabcs20-pd15-10
Autor:
Irena Leite, Victor Andrianov, Diana Zelencova-Gopejenko, Einars Loza, Iveta Kazhoka-Lapsa, Ilona Domracheva, Marta Stojak, Stefan Chlopicki, Ivars Kalvins
Publikováno v:
Chemistry of Heterocyclic Compounds. 57:1235-1235
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb8e0674d88befbf061f85fa9b43fa3d
https://doi.org/10.1007/s10593-021-03048-5
https://doi.org/10.1007/s10593-021-03048-5
Autor:
Einars Loza, Ilona Mandrika, Olga Bobileva, Ramona Petrovska, Janis Klovins, Gunars Duburs, Martins Ikaunieks
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:4314-4329
Novel series of compounds consisting of 2-amidocyclohex-1-ene carboxylate and phenyl parts which are connected by enyne (compounds 2a-f), but-1-yne (compounds 4a-j), and phenylethylene (compounds 5a-f) linkers as HCA2 full agonists were designed and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e1349627d895ce884d43cf6a463ea4
https://doi.org/10.1016/j.bmc.2017.06.028
https://doi.org/10.1016/j.bmc.2017.06.028
Autor:
Einars Loza, Daina Lola, Marina Makrecka-Kuka, Edgars Liepinsh, Maija Dambrova, Karlis Vilks, Solveiga Grinberga, Janis Kuka, Reinis Vilskersts, Elina Makarova, Unigunde Antone, Eduards Sevostjanovs, Kristine Volska
Publikováno v:
BioFactors. 43:718-730
Acylcarnitine accumulation has been linked to perturbations in energy metabolism pathways. In this study, we demonstrate that long-chain (LC) acylcarnitines are active metabolites involved in the regulation of glucose metabolism in vivo. Single-dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e71bb4bfca413b89512ed95b1e73c6e6
https://doi.org/10.1002/biof.1378
https://doi.org/10.1002/biof.1378