Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Einar Sulheim"'
Publikováno v:
Cancer Medicine, Vol 12, Iss 10, Pp 11589-11601 (2023)
Abstract Immunocompetent murine models are important tools for preclinical evaluation of immunotherapies. Here, six different immunocompetent tumor models based on four different cell lines were characterized, including metastatic lung cancer (CMT 16
Externí odkaz:
https://doaj.org/article/cd74db9f58e54cf69fd13d03e1d5387f
Autor:
Mette Elise Tunset, Hanne Haslene-Hox, Tim Van Den Bossche, Arne Einar Vaaler, Einar Sulheim, Daniel Kondziella
Publikováno v:
PeerJ, Vol 8, p e9714 (2020)
Extracellular vesicles (EVs) are cell-derived structures that transport proteins, lipids and nucleic acids between cells, thereby affecting the phenotype of the recipient cell. As the content of EVs reflects the status of the originating cell, EVs ca
Externí odkaz:
https://doaj.org/article/90daaa6a514c4d498b6005c16144992f
Autor:
Habib Baghirov, Sofie Snipstad, Einar Sulheim, Sigrid Berg, Rune Hansen, Frits Thorsen, Yrr Mørch, Catharina de Lange Davies, Andreas K O Åslund
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191102 (2018)
The treatment of brain diseases is hindered by the blood-brain barrier (BBB) preventing most drugs from entering the brain. Focused ultrasound (FUS) with microbubbles can open the BBB safely and reversibly. Systemic drug injection might induce toxici
Externí odkaz:
https://doaj.org/article/46b56ab6ef9b467a8cea41c9f0493381
Autor:
Shubaash Anthiya, Süleyman Can Öztürk, Hamdullah Yanik, Ece Tavukcuoglu, Adem Şahin, Dhrubajyoti Datta, Klaus Charisse, David Moreira Álvarez, María Isabel Loza, Alfonso Calvo, Einar Sulheim, Simon Loevenich, Geir Klinkenberg, Ruth Schmid, Muthiah Manoharan, Güneş Esendağlı, Maria Jose Alonso
K-RAS is a highly relevant oncogene that is mutated in approximately 90% of pancreatic cancers and 20–25% of lung adenocarcinomas. The aim of this work was to develop a new anti-KRAS siRNA therapeutic strategy through the engineering of functionali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d546c8f9a778fb6999cb14a0ee3108
https://hdl.handle.net/10347/30619
https://hdl.handle.net/10347/30619
Autor:
Ýrr Mørch, Einar Sulheim, Catharina de Lange Davies, André Pedersen, Andreas Åslund, Sofie Snipstad, Rune Hansen, Sigrid Berg
Publikováno v:
Ultrasound in Medicine and Biology
Delivery of drugs and nanomedicines to tumors is often heterogeneous and insufficient and, thus, of limited efficacy. Microbubbles in combination with ultrasound have been found to improve delivery to tumors, enhancing accumulation and penetration. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fc1eeaf8115fd7e01d079c78b2b336
https://doi.org/10.1016/j.ultrasmedbio.2020.12.026
https://doi.org/10.1016/j.ultrasmedbio.2020.12.026
Autor:
Serina Ng, Andrew John Healey, Per Christian Sontum, Svein Kvåle, Sverre H. Torp, Einar Sulheim, Daniel Von Hoff, Haiyong Han
Publikováno v:
Journal of Controlled Release
Pancreatic ductal adenocarcinomas respond poorly to chemotherapy, in part due to the dense tumor stroma that hinders drug delivery. Ultrasound (US) in combination with microbubbles has previously shown promise as a means to improve drug delivery, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb91e2a05779ea7311d2c81a9154101
https://hdl.handle.net/11250/3053212
https://hdl.handle.net/11250/3053212
Autor:
Markus Fusser, Anders Øverbye, Abhilash D. Pandya, Ýrr Mørch, Sven Even Borgos, Wanja Kildal, Sofie Snipstad, Einar Sulheim, Karianne Giller Fleten, Hanne Arenberg Askautrud, Olav Engebraaten, Kjersti Flatmark, Tore Geir Iversen, Kirsten Sandvig, Tore Skotland, Gunhild M. Mælandsmo
Publikováno v:
Journal of Controlled Release. 349:1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fec0b55bcf553fbd3e6552e175983798
https://doi.org/10.1016/j.jconrel.2022.06.040
https://doi.org/10.1016/j.jconrel.2022.06.040
Autor:
Anders Øverbye, Abhilash D. Pandya, Olav Engebraaten, Tore Skotland, Tore Geir Iversen, Markus Fusser, Ýrr Mørch, Sofie Snipstad, Kjersti Flatmark, Wanja Kildal, Kirsten Sandvig, Sven Even F. Borgos, Hanne A. Askautrud, Einar Sulheim, Karianne G. Fleten, Gunhild Mari Mælandsmo
Publikováno v:
Journal of Controlled Release
Source at https://doi.org/10.1016/j.jconrel.2018.11.029. Licensed CC BY-NC-ND 4.0. The effect of poly(2-ethyl-butyl cyanoacrylate) nanoparticles containing the cytotoxic drug cabazitaxel was studied in three breast cancer cell lines and one basal-lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2686116ad4053e3e4a442ec00b8dd28d
https://doi.org/10.1016/j.jconrel.2018.11.029
https://doi.org/10.1016/j.jconrel.2018.11.029
Autor:
Ingunn Hanson, Yrr Mørch, Yves Boucher, Einar Sulheim, Krister Vikedal, Catharina de Lange Davies, Sofie Snipstad
Publikováno v:
Advanced therapeutics
Drug delivery to tumors is challenging due to biological barriers obstructing effective delivery. Sonopermeation with ultrasound and microbubbles has been shown to improve therapeutic effect of many classes of drugs, but the underlying mechanism is n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c9a66367fb413da68610c1fe01fe99
https://hdl.handle.net/11250/2987266
https://hdl.handle.net/11250/2987266
Autor:
Einar Sulheim, Catharina de Lange Davies, Astrid Hyldbakk, Deborah K. Hill, Stein-Martin Tilrum Fagerland, Sigrid Berg, Jana Kim, Sofie Snipstad
Publikováno v:
Ultrasound in Medicine and Biology
Ultrasound (US) in combination with microbubbles (MB) has had promising results in improving delivery of chemotherapeutic agents. However, most studies are done in immunodeficient mice with xenografted tumors. We used two phenotypes of the spontaneou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ecc5c3f488c26d9778ab4d63dfeef60
https://hdl.handle.net/11250/2722213
https://hdl.handle.net/11250/2722213