Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Eimear Lagan"'
Autor:
Mimmi LE Lundahl, Morgane Mitermite, Dylan Gerard Ryan, Sarah Case, Niamh C Williams, Ming Yang, Roisin I Lynch, Eimear Lagan, Filipa M Lebre, Aoife L Gorman, Bojan Stojkovic, Adrian P Bracken, Christian Frezza, Frederick J Sheedy, Eoin M Scanlan, Luke AJ O'Neill, Stephen V Gordon, Ed C Lavelle
Publikováno v:
eLife, Vol 11 (2022)
Macrophages are a highly adaptive population of innate immune cells. Polarization with IFNγ and LPS into the ‘classically activated’ M1 macrophage enhances pro-inflammatory and microbicidal responses, important for eradicating bacteria such as M
Externí odkaz:
https://doaj.org/article/dfb7ec54071d42919b18133a72d40a8b
Autor:
Mimmi L. E. Lundahl, Morgane Mitermite, Dylan G. Ryan, Sarah Case, Niamh C. Williams, Ming Yang, Roisin I. Lynch, Eimear Lagan, Filipa Lebre, Aoife L. Gorman, Bojan Stojkovic, Adrian P. Bracken, Christian Frezza, Fred J. Sheedy, Eoin M. Scanlan, Luke A. J. O’Neill, Stephen V. Gordon, Ed C. Lavelle
Peer reviewed: True
Funder: Trinity College Dublin; FundRef: http://dx.doi.org/10.13039/501100001637
Macrophages are a highly adaptive population of innate immune cells. Polarization with IFNγ and LPS into the 'classically activated' M1 ma
Funder: Trinity College Dublin; FundRef: http://dx.doi.org/10.13039/501100001637
Macrophages are a highly adaptive population of innate immune cells. Polarization with IFNγ and LPS into the 'classically activated' M1 ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3775922b877e1191514361842bf45b
Autor:
Vivien Grant, Dáire Gannon, Eimear Lagan, Neza Alfazema, Craig Monger, Steven M. Pollard, Hannah K. Neikes, Orla Deevy, Darren J. Fitzpatrick, Raul Bardini Bressan, Evan Healy, Maria-Angeles Marqués-Torrejón, Adrian P. Bracken, Anthony M Doherty, Gerard L. Brien
Publikováno v:
Brien, G L, Bressan, R B, Monger, C, Gannon, D, Lagan, E, Doherty, A M, Healy, E, Neikes, H, Fitzpatrick, D J, Deevy, O, Grant, V, Marqués-Torrejón, M-A, Alfazema, N, Pollard, S M & Bracken, A P 2021, ' Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells ', Nature Genetics, vol. 53, no. 8, pp. 1221-1232 . https://doi.org/10.1038/s41588-021-00897-w
Driver mutations in genes encoding histone H3 proteins resulting in p.Lys27Met substitutions (H3-K27M) are frequent in pediatric midline brain tumors. However, the precise mechanisms by which H3-K27M causes tumor initiation remain unclear. Here, we u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e035e9444657c8de908bac924ca715af
https://doi.org/10.1038/s41588-021-00897-w
https://doi.org/10.1038/s41588-021-00897-w
Autor:
Gerard L, Brien, Raul Bardini, Bressan, Craig, Monger, Dáire, Gannon, Eimear, Lagan, Anthony M, Doherty, Evan, Healy, Hannah, Neikes, Darren J, Fitzpatrick, Orla, Deevy, Vivien, Grant, Maria-Angeles, Marqués-Torrejón, Neza, Alfazema, Steven M, Pollard, Adrian P, Bracken
Publikováno v:
Nature genetics. 53(8)
Driver mutations in genes encoding histone H3 proteins resulting in p.Lys27Met substitutions (H3-K27M) are frequent in pediatric midline brain tumors. However, the precise mechanisms by which H3-K27M causes tumor initiation remain unclear. Here, we u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9078ae308fdb4ebfdd0df379dab2a538
https://pubmed.ncbi.nlm.nih.gov/34294917
https://pubmed.ncbi.nlm.nih.gov/34294917