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pro vyhledávání: '"Eilis Byrne"'
Autor:
Navdeep K. Sahota, Samantha Burns, Daniel G. Hayward, Guojie Mao, Paul Workman, Ian Collins, Eilis Byrne, Lisa Pickard, Yvette Newbatt, Wynne Aherne, Andrew M. Fry
Publikováno v:
SLAS Discovery. 15:918-927
Nek2 is a serine/threonine protein kinase that localizes to the centrosome and is implicated in mitotic regulation. Overexpression of Nek2 induces premature centrosome separation and nuclear defects indicative of mitotic errors, whereas depletion of