Výsledky vyhledávání - "Eileigh Kadijk"

Thiopurines activate an antiviral unfolded protein response that blocks influenza A virus glycoprotein accumulation

Autor: Michel Roberge, Denys A. Khaperskyy, Mariel Kleer, Brett A. Duguay, Patrick D Slaine, Craig McCormick, Aruna D. Balgi, Eric S. Pringle, Shan Ying, Eileigh Kadijk

Publikováno v: Journal of Virology

Secreted and transmembrane proteins are synthesized in the endoplasmic reticulum (ER), where they are folded and modified prior to transport. Many viruses rely on the ER for the synthesis and processing of viral glycoproteins that will ultimately be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e4922e44f95b37cc6bb409a439778b
https://pubmed.ncbi.nlm.nih.gov/33762409

Zobrazit plný text záznamu

Thiopurines activate an antiviral unfolded protein response that blocks viral glycoprotein accumulation in cell culture infection model

Autor: Michel Roberge, Brett A. Duguay, Mariel Kleer, Patrick D Slaine, Aruna D. Balgi, Eric S. Pringle, Craig McCormick, Denys A. Khaperskyy, Eileigh Kadijk, Shan Ying

Enveloped viruses, including influenza A viruses (IAVs) and coronaviruses (CoVs), utilize the host cell secretory pathway to synthesize viral glycoproteins and direct them to sites of assembly. Using an image-based high-content screen, we identified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0a06a665cc30ded3d0bba5547315d21
https://doi.org/10.1101/2020.09.30.319863

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání