Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Eileena F. Giurini"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Toll-like receptors (TLRs) are well-known for their role in cancer development as well as in directing anti-tumor immunity. Because TLRs have also been implicated in the innate recognition of the influenza virus, it was of great interest to investiga
Externí odkaz:
https://doaj.org/article/7da4cd63a6284dea8f2fc2aeb596c172
Publikováno v:
Vaccines, Vol 9, Iss 12, p 1497 (2021)
Currently approximately 10 million people die each year due to cancer, and cancer is the cause of every sixth death worldwide. Tremendous efforts and progress have been made towards finding a cure for cancer. However, numerous challenges have been fa
Externí odkaz:
https://doaj.org/article/30afcbc5896f46fea8e31f68f975b6f7
Autor:
Sharad Goyal, Howard L Kaufman, Andrew Zloza, Ann W Silk, Vineet Gupta, Shang-Jui Wang, Bruce G Haffty, Nicole R LeBoeuf, Sachin R Jhawar, Jose A Guevara-Patino, Timothy M Kuzel, Jochen Reiser, Aditya Thandoni, Praveen K Bommareddy, Jenna H Newman, Amanda L Marzo, Preston Daniels, Devora Schiff, Darrion Mitchell, Christopher Simmons, Ahmed Lasfar, Eileena F Giurini
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 7 (2023)
Background Immunotherapies are becoming front-line treatments for many advanced cancers, and combinations of two or more therapies are beginning to be investigated. Based on their individual antitumor capabilities, we sought to determine whether comb
Externí odkaz:
https://doaj.org/article/aa466472bc1745428fedfc56b28b3f77
Following the breakthrough of immune check point inhibitors (ICIs), a new era of immuno-oncology agents has emerged and established immunotherapy as a part of cancer treatment. Despite the improving outcomes of ICIs, many patients with initial respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2cafbe59e98861c614f43fda5a59b68
https://doi.org/10.1101/2022.06.30.498305
https://doi.org/10.1101/2022.06.30.498305
Autor:
Jiaqi Wu, Francesca V. LoBianco, Lawrence B. Schook, Maureen Regan, Kelly D. Garcia, Lobna Elkhadragy, Aisha Qazi, Herbert E. Whiteley, Matthew C. Stewart, Faith M. Thomas, Grace Guzman, Lauretta A. Rund, Regina M. Schwind, F. Edward Boas, Ron C. Gaba, Hanna H. Chen, Eileena F. Giurini, Kyle M. Schachtschneider, Mohammed El-Kebir, Sulalita Chaki, Mario F. Neto, Jordan L. Newson
Publikováno v:
Oncotarget
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide. New animal models that faithfully recapitulate human HCC phenotypes are required to address unmet clinical needs and advance standard-of-care therapeutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a95655aec3b4a8f4b2e1c658316c8ec
https://doi.org/10.18632/oncotarget.27647
https://doi.org/10.18632/oncotarget.27647
Autor:
Janet Zayas, Ruchi Roy, Sunil K Singh, Kaylee Delgado, Stephen J Wood, Mohamed F Mohamed, Dulce M Frausto, Yasmeen A Albalawi, Thea P Price, Ricardo Estupinian, Eileena F Giurini, Timothy M Kuzel, Andrew Zloza, Jochen Reiser, Sasha H Shafikhani
Publikováno v:
eLife, Vol 11 (2022)
Infection is a major co-morbidity that contributes to impaired healing in diabetic wounds. Although impairments in diabetic neutrophils have been blamed for this co-morbidity, what causes these impairments and whether they can be overcome, remain lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef202a187205b29c64154cdc27d49e06
https://elifesciences.org/articles/72071
https://elifesciences.org/articles/72071
Autor:
Joseph R. Broucek, Eileena F. Giurini, Nora L. Herzog, Lisa K. Denzin, Gabriel Guevara-Aleman, C. Brent Chesson, Ricardo Estupinian, Marco Rossi, Mary J. Fidler, Raquel E. Redondo, Jai S. Rudra, Joyce Paras, Jochen Reiser, Amanda L. Marzo, Jyoti Malhotra, Shang Jui Wang, Emily S. Ruiz, Stuti Buddhadev, Howard L. Kaufman, Saeed Tarabichi, Sachin R. Jhawar, Frederick J. Kohlhapp, Daniel J. Medina, Mones M. Aboelatta, David Rotter, Shengguo Li, Leonard Y. Lee, Vineet Gupta, John Langenfeld, Ann W. Silk, Russell J. Pepe, Kajal Gupta, Timothy M. Kuzel, Jason M. Schenkel, Derek B. Sant'Angelo, Abdulkareem Abed, Jenna H. Newman, Michael J. Lee, Praveen K. Bommareddy, Salvatore M. Aspromonte, Ahmed Lasfar, Eric A. Singer, Michael P. Kane, Christina Nowicki, Arnold B. Rabson, Andrew Zloza, Paul G. Thomas, Josef W. Goldufsky
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Immunotherapy has revolutionized cancer treatment, yielding unprecedented long-term responses and survival. However, a significant proportion of patients remain refractory, which correlates with the absence of immune-infiltrated (“hot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab3df47d5bd7978884f383d0b95e201
https://doi.org/10.1073/pnas.1904022116
https://doi.org/10.1073/pnas.1904022116
Autor:
Janet Zayas, Ruchi Roy, Sunil K Singh, Kaylee Delgado, Stephen J Wood, Mohamed F Mohamed, Dulce M Frausto, Yasmeen A Albalawi, Thea P Price, Ricardo Estupinian, Eileena F Giurini, Timothy M Kuzel, Andrew Zloza, Jochen Reiser, Sasha H Shafikhani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::715ecd28aea77c11b7e5c279e412acae
https://doi.org/10.7554/elife.72071.sa2
https://doi.org/10.7554/elife.72071.sa2
Autor:
Jochen Reiser, Ruchi Roy, Janet Zayas, Timothy M. Kuzel, Sasha H. Shafikhani, Dulce M. Frausto, Mohamed F. Mohamed, Stephen Wood, Ricardo Estupinian, Eileena F. Giurini, Andrew Zloza
Infection is a major co-morbidity that contributes to impaired healing in diabetic wounds. Although impairments in diabetic neutrophils have been blamed for this co-morbidity, what causes these impairments and whether they can be overcome, remain lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10687e3bf305f2d56bea57f78c99542b
https://doi.org/10.1101/2021.09.09.459638
https://doi.org/10.1101/2021.09.09.459638
Autor:
Lawrence B. Schook, Hanna H. Chen, Kyle M. Schachtschneider, Eileena F. Giurini, Jordan L. Newson, Ron C. Gaba, Mario F. Neto
Publikováno v:
Cancer Research. 78:4094-4094
Preclinical animal models represent pivotal tools to develop novel therapeutics. While murine models are commonly used in preclinical drug research, many agents that show promise in mouse studies ultimately fail in human clinical trials. In contrast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::398bc3fe8600a0d345f0223d5950d011
https://doi.org/10.1158/1538-7445.am2018-4094
https://doi.org/10.1158/1538-7445.am2018-4094