Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Eileen Shiuan"'
Autor:
May Myint Thanda Kyaw, Eileen Shiuan, Ariannette Yaniz Robledo Gomez, Arun S. Singh, Nasser Abdo
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 878-885 (2023)
Epithelioid angiosarcoma is an extremely rare subtype of cardiac angiosarcoma that is highly aggressive and associated with poor prognosis. Due to its rare nature, the epidemiology and pathogenesis of this disease are not well-known. Thus, effective
Externí odkaz:
https://doaj.org/article/7eb934346ad14ad6a598cb9ac6cd478a
Autor:
Lu Sun, Jenny C. Kienzler, Jeremy G. Reynoso, Alexander Lee, Eileen Shiuan, Shanpeng Li, Jiyoon Kim, Lizhong Ding, Amber J. Monteleone, Geoffrey C. Owens, Joanna J. Phillips, Richard G. Everson, David Nathanson, Timothy F. Cloughesy, Gang Li, Linda M. Liau, Willy Hugo, Won Kim, Robert M. Prins
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 17 (2023)
In comparison with responses in recurrent glioblastoma (rGBM), the intracranial response of brain metastases (BrM) to immune checkpoint blockade (ICB) is less well studied. Here, we present an integrated single-cell RNA-Seq (scRNA-Seq) study of 19 IC
Externí odkaz:
https://doaj.org/article/3cb05e2876a542d2be72e98032f7abe4
Autor:
Eileen Shiuan, Ashwin Inala, Shan Wang, Wenqiang Song, Victoria Youngblood, Jin Chen, Dana M. Brantley-Sieders
Publikováno v:
F1000Research, Vol 9 (2020)
Background: The conventional dogma of treating cancer by focusing on the elimination of tumor cells has been recently refined to include consideration of the tumor microenvironment, which includes host stromal cells. Ephrin-A1, a cell surface protein
Externí odkaz:
https://doaj.org/article/d77f234c236642d4b20c33c4c9dc8270
Publikováno v:
Journal of thrombosis and thrombolysis, vol 54, iss 2
Heparin-induced thrombocytopenia (HIT) occurs with the development of IgG antibodies that bind complexes of heparin and platelet factor 4 (PF4), which activate platelets and result in a profoundly prothrombotic condition. In rare instances, this synd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ee93ee8d70188d9ba3f929da0e2357
https://escholarship.org/uc/item/4kt94191
https://escholarship.org/uc/item/4kt94191
Publikováno v:
Oncogene
More than twenty-five years of research and pre-clinical validation have defined EphA2 receptor tyrosine kinase as a promising molecular target for clinical translation in cancer treatment. Molecular, genetic, biochemical, and pharmacological targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392d39d136623ae936a6272ca77c3ff6
https://doi.org/10.1038/s41388-021-01714-8
https://doi.org/10.1038/s41388-021-01714-8
Autor:
Joseph T. Schneider, Wade T. Iams, Catherine B. Meador, Lucy L. Wang, Eileen Shiuan, IlaSri B. Summitt, Kelli L. Boyd, Marc T. Roth, Zhiguo Zhao, Jennifer Bordeaux, Jeremy L. Warner, Christine M. Lovly, Christine Vaupel
Publikováno v:
Journal of Thoracic Oncology. 14:1970-1981
Background Approximately 10% of patients with SCLC develop a paraneoplastic syndrome (PNS). Neurologic PNS are thought to improve prognosis, which we hypothesized is related to increased tumor-infiltrating lymphocytes and immune recognition. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81dac1bd986021b965585be6b440847
https://doi.org/10.1016/j.jtho.2019.05.042
https://doi.org/10.1016/j.jtho.2019.05.042
Autor:
James A. Nathan, Siyuan Zhang, Shan Wang, Jin Chen, Eileen Shiuan, Deanna N. Edwards, Ariel L. Raybuck, Margaret M. Allaman, Rebecca S. Cook, Keith T. Wilson, Mark Boothby, Qingfei Wang, Dana M. Brantley-Sieders, Sung Hoon Cho, David G. DeNardo
Publikováno v:
JCI Insight
A tumor blood vessel is a key regulator of tissue perfusion, immune cell trafficking, cancer metastasis, and therapeutic responsiveness. mTORC1 is a signaling node downstream of multiple angiogenic factors in the endothelium. However, mTORC1 inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affd2c6a967feaabcb5b1f004409fd92
https://www.repository.cam.ac.uk/handle/1810/309343
https://www.repository.cam.ac.uk/handle/1810/309343
Given the success of both targeted and immunotherapies against cancer, there is increasing utility for identifying targeted agents that also promote anti-tumor immunity. EphA2 is a receptor tyrosine kinase that contributes to tumor growth and metasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a08de8bc8fa03a9f76c82090dacee8
Autor:
Jin Chen, Eileen Shiuan
Publikováno v:
Cancer Research. 76:6452-6457
The family of Eph receptor tyrosine kinases and their ephrin ligands regulate a diverse array of physiologic processes, such as axonal guidance, bone remodeling, and immune cell development and trafficking. Eph/ephrin interactions have also been impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11750e7a0e8c72dbef214beb5e7088cf
https://doi.org/10.1158/0008-5472.can-16-1521
https://doi.org/10.1158/0008-5472.can-16-1521
Autor:
Shan Wang, Laura C. Kim, Jin Chen, Albert B. Reynolds, Eileen Shiuan, Deanna N. Edwards, Verra M. Ngwa, Dana M. Brantley-Sieders
Publikováno v:
Science signaling. 10(508)
Malignant tumors reprogram cellular metabolism to support cancer cell proliferation and survival. Although most cancers depend on a high rate of aerobic glycolysis, many cancer cells also display addiction to glutamine. Glutamine transporters and glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4717912ed925fc692d24a76c8637e07
https://pubmed.ncbi.nlm.nih.gov/29208682
https://pubmed.ncbi.nlm.nih.gov/29208682