Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Eileen Seward"'
Autor:
Bryan K. Chan, Eileen Seward, Michael Lainchbury, Thomas F. Brewer, Le An, Toby Blench, Matthew W. Cartwright, Grace Ka Yan Chan, Edna F. Choo, Jason Drummond, Richard L. Elliott, Emanuela Gancia, Lewis Gazzard, Baihua Hu, Graham E. Jones, Xifeng Luo, Andrew Madin, Sushant Malhotra, John G. Moffat, Jodie Pang, Laurent Salphati, Christopher J. Sneeringer, Craig E. Stivala, Binqing Wei, Weiru Wang, Ping Wu, Timothy P. Heffron
Publikováno v:
ACS Med Chem Lett
[Image: see text] Hematopoietic progenitor kinase 1 (HPK1) is implicated as a negative regulator of T-cell receptor-induced T-cell activation. Studies using HPK1 kinase-dead knock-in animals have demonstrated the loss of HPK1 kinase activity resulted
Publikováno v:
Journal of the American Chemical Society. 113:5410-5419
This paper describes a comprehensive 1 H NMR analysis of the inclusion complexation of neutral 2,6-disubstituted naphtalene and para-disubstituted benzene derivatives by cyclophanes. The major attractive host-guest interactions in these complexes are
Publikováno v:
Journal of the American Chemical Society. 112:1783-1790
Publikováno v:
ChemInform. 21
Autor:
François Diederich, Eileen Seward
Publikováno v:
Tetrahedron Letters. 28:5111-5114
The synthesis of the novel macrocyclic host 1 incorporating an isoalloxazine moiety as model for active sites of flavoenzymes is described. The complexation between oxidized and reduced flavin-host and aromatic guests is analyzed in aqueous solution.
Autor:
Richard J. Loncharich, Stephen B. Ferguson, Frank K. Brown, Eileen Seward, K. N. Houk, François Diederich
Publikováno v:
The Journal of Organic Chemistry. 53:3479-3491
Autor:
François Diederich, Elizabeth M. Sanford, Eileen Seward, Stephen B. Ferguson, M. Uyeki, M. Hester
Publikováno v:
Pure and Applied Chemistry. 61:1523-1528
Synthetic cyclophane hosts form highly structured complexes with aromatic substrates in aqueous and organic solutions. Solvation-desolvation processes are recognized as a central factor that determines the stability of these complexes. From comparati
Autor:
P. Inocencio-Szweda, François Diederich, Carolyn B. Knobler, Eileen Seward, Elizabeth M. Sanford, A. Chou, Stephen B. Ferguson
Publikováno v:
The Journal of Organic Chemistry. 53:5593-5595
Autor:
Stephen B. Ferguson, François Diederich, Eileen Seward, Richard J. Loncharich, K. N. Houk, Frank K. Brown
Publikováno v:
ChemInform. 20
Publikováno v:
Chemischer Informationsdienst. 14
MNDO calculations on closo-borane anions are used to assess the accuracy of a recently reported theory of their electronic structure and bonding. The assumptions and results of the theory are found to be fully supported, and parameters are determined